Results 61 to 70 of about 427,317 (231)

The ages of alleles and a coalescent

open access: yesAdvances in Applied Probability, 1986
A new coalescent is introduced to study the genealogy of a sample from the infinite-alleles model of population genetics. This coalescent also records the age ordering of alleles in the sample. The distribution of this process is found explicitly for the Moran model, and is shown to be robust for a wide class of reproductive schemes.Properties of the ...
Donnelly, P, Tavare, S
openaire   +3 more sources

Allele Frequencies Database [PDF]

open access: yesTransfusion Medicine and Hemotherapy, 2014
This review describes a database for the collection, archiving, sorting, searching and display of gene and allele frequencies for immunogenetic genes.
Faviel F. Gonzalez-Galarza   +3 more
openaire   +3 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

ABCA1 rs1883025 and CYP4F2 rs2108622 Gene Polymorphism Association with Age-Related Macular Degeneration and Anti-VEGF Treatment

open access: yesMedicina, 2021
Background and Objectives: The age-related macular degeneration (AMD) pathophysiology is multifactorial, as it consists of interactions between aging, genetic, and environmental factors.
Ruta Mockute   +4 more
doaj   +1 more source

Spatial gene drives and pushed genetic waves

open access: yes, 2017
Gene drives have the potential to rapidly replace a harmful wild-type allele with a gene drive allele engineered to have desired functionalities. However, an accidental or premature release of a gene drive construct to the natural environment could ...
Nelson, David R.   +2 more
core   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Polymorphism of Blood Serum Protein- Transferrin, Ceruloplasmin, Albumin- in Sheep of Karabakh Breed and the Relationship with the Natural Resistance Towards Epizootic Aphtae

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
New genetic methods are currently used in selection activities of agricultural animals, based on polymorph genetic determination systems, which, serving as genetic markers, enable studying animal genealogy, alelofon, genotypes.
Manvel Badalyan   +2 more
doaj  

Association of SOCS5 gene polymorphism with allergic bronchial asthma [PDF]

open access: yesТерапевтический архив, 2019
Aim: to study the association of mononucleotide polymorphism rs6737848 SOCS5 gene with the risk of development of allergic bronchial asthma. Material and methods.
A B Averyanov   +4 more
doaj   +1 more source

Molecular Identification of Bacillus Isolated from Korean Water Deer (Hydropotes inermis argyropus) and Striped Field Mouse (Apodemus agrarius) Feces by Using an SNP-Based 16S Ribosomal Marker

open access: yesAnimals, 2022
Ambiguous, heterogeneous, endospore-forming Bacillus species, notably Bacillus cereus, often produce fatal toxins that threaten human health. We identified Bacillus from wild animal fecal samples (n = 80), including the Korean water deer (n = 25) and ...
Md-Mafizur Rahman   +2 more
doaj   +1 more source

Allele mining strategies: principles and utilisation for blast resistance genes in rice (Oryza sativa L.) [PDF]

open access: yes, 2015
Allele mining is a promising way to dissect naturally occurring allelic variants of candidate genes with essential agronomic qualities. With the identification, isolation and characterisation of blast resistance genes in rice, it is now possible to ...
Abdul Latif, Mohammad   +6 more
core  

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