Results 81 to 90 of about 876,901 (295)
Allele-informed copy number evaluation of plasma DNA samples from metastatic prostate cancer patients: the PCF_SELECT consortium assay
, 2022 Sequencing of cell-free DNA (cfDNA) in cancer patients’ plasma offers a minimally-invasive solution to detect tumor cell genomic alterations to aid real-time clinical decision-making.Lena Karapagniotou (12906311), Debra Enting (12906308), Emma Colliver (10065232), Chi-wah Lok (12906134), Kieren Allinson (9729795), Sergio Quezada (594405), Sanjay Popat (18278), Kerstin Thol (12906215), Abby Sharp (12906380), Karla Pearce (12906242), John Bridgewater (12906122), Claudia Lee (2052127), Abigail Bunkum (12906191), Grant Stewart (3616418), Bruce Tanchel (12906347), Ron Sinclair (4342210), Faye Gishen (3514760), Husayn Pallinkonda (12906272), Pedro Oliveira (199037), Haixi Yan (12906251), Stephan Beck (5246), Maise Al-Bakir (12906149), William Hill (7806), Aida Murra (11932175), GianMarco Leone (12906212), Oriol Pich (5327108), Lyra Del Rosario (11306172), Ben Deakin (12906305), Hollie Bancroft (12906353), Andew Rowan (12906284), Christina Messiou (6632633), Charlotte Spencer (3747700), Molly O'Flaherty (12064271), Caroline Dive (421487), PEACE Consortium (9622124), Iain McNeish (757957), David Moore (30526), Wing-Kin Liu (12906176), Andreas Michael Schmitt (12906260), Ursula McGovern (9573458), Samantha Holden (12906368), Dionysis Papadatos-Pastos (12906125), Camille Gerard (12906257), Caroline Stirling (12906236), Kitty Chan (628075), Lavinia Spain (8985068), Andrew Furness (11159853), Paulina Prymas (11903540), Neil Magno (12906182), Monica Sivakumar (12906140), Anna Wingate (12906113), Charlotte Ferris (8823053), Sheeba Irshad (9149291), Anna Green (3502100), Constantine Alifrangis (9951020), Shobhit Baijal (12906344), Ariana Huebner (12906128), Melek Akay (12906164), Heather Shaw (819340), Emma Beddowes (6175112), Kai-Keen Shiu (8396175), Nnenna Kanu (12906152), Alison Cluroe (12906323), Arash Latifoltojar (4221157), Lauren Terry (12906290), Mat Carter (12906338), James Brenton (3567290), Yvonne Summers (594452), Mark A Rubin (12906389), Kema Peat (11932172), Michelle Dietzen (3476288), Alistair Magness (12906170), Siow-Ming Lee (519588), Mihaela Angelova (10065229), Tom Watkins (12906143), Andrew Robinson (19205), Sophie Ward (7020515), James Larkin (715545), Gary Middleton (594406), Tanya Ahmad (594426), Robert E Hynds (8156319), Amy Kerr (6921317), Sarah Benafif (9664184), Takahiro Karasaki (12906188), James Spicer (222853), Jo Dransfield (12906341), Rodelaine Wilson (12906365), Andrew Kidd (12906329), Francesca Demichelis (48428), Olivia Curtis (11932208), David R Pearce (10003751), Samuel Gamble (12906218), Ula Mahadeva (11387159), Jenny Z Xiang (12906110), Gareth Wilson (3119967), Mariam Jamal-Hanjani (594401), Kim Edmonds (8266020), Alessandro Romanel (191708), Blanca Trujillo Alba (12906158), Geoffrey Hugang Feng (12906281), Peter Hill (47898), Sanjay Jogai (4060867), Irene Lobon (10494904), Peter Colloby (12906359), Anne Laure Cattin (12906278), Rachel Leslie (12906386), Sam Janes (594414), Mary Falzon (594410), Peter Ellery (9567899), Peter Van Loo (9838), Mairead McKenzie (12906377), Sebastian Brandner (84430), Daqi Deng (11932169), Vittorio Barbe (12906197), Patricia Roxburgh (571338), Sioban Fraser (3452780), Kate Young (4541365), Sarah Howlett (12906314), Mark Linch (9419387), Katey Enfield (5022971), Lisa Pickering (9304160), Ashish Chandra (127599), Martin Collard (12906350), John Le Quesne (594408), Merche Jimenez-Linan (12906320), Fabio Gomes (197095), Piotr Pawlik (12906233), Debra Josephs (6814505), Teresa Marafioti (7741250), Cristina Naceur-Lombardelli (4513306), Foteini Athanasopoulou (12906185), Teerapon Sahwangarrom (12906224), Paddy Stone (10336092), Roberto Salgado (8458), Salma Kadiri (6921314), Alexander Frankell (12906179), Tim Maughan (4450264), Kayleigh Kelly (11932178), Steve Hazell (9304154), Kevin Blyth (12906332), Sarah Aitken (5612171), Carlos Martinez Ruiz (12906146), James Reading (12906155), Jennifer Biano (12906293), Nadia Yousaf (7673699), Elena Provenzano (248417), Matthew Krebs (594441), Nicholas McGranahan (594459), Gianmarco Leone (9255806), Samra Turajlic (7784021), Michael Sigouros (12906104), Antonia Toncheva (11942057), Justine Korteweg (11932157), Daniel Wetterskog (7130912), Adrienne Flanagan (12906167), Adrian Tookman (3529922), Will Drake (12906239), Sharmistha Ghosh (4375606), Anne Thomas (90885), Alex Coulton (12906275), Lucy Holt (11932151), Ana Ortega-Franco (12906335), Charles Swanton (236153), Mahedi Hasan (12906209), Ben Shum (11306181), Ian Tomlinson (146463), Annika Fendler (169443), Tina Mackay (12906302), Andrew Rowan (382296), Peter Campbell (475798), Othman Al-Sawaf (424154), Sophia Wong (12906230), Blanca Trujillo (12906101), Osvaldas Vainauskas (12906203), Martin Forster (3565799), Vasiliki Michalarea (12906317), Miriam Mitchison (11387160), Bernard Olisemeke (12906362), Brian Hanley (35092), Francesco Orlando (12906098), Peter Parker (668602), Jacqui Shaw (7728557), Hardeep Mudhar (12906269), Tania Fernandes (12906371), Imran Noorani (12906194), Gerald Langman (594442), Himisha Beltran (5779568), Selvaraju Veeriah (594454), Emma Nye (206817), Carlos Caldas (1042), Fiona Byrne (11306166), Blanche Hampton (12906374), Rebecca Fitzgerald (416531), Lara-Rose Iredale (12906299), Gert Attard (9927022), Anna Paterson (12906326), Nikki Hunter (11159838), Dean Fennell (594416), Mary Mangwende (11387156), Lewis Au (8266032), Lauren Grostate (12906245), Elias Pintus (12482953), Krijn Dijkstra (12906131), Analyn Lucanas (12906266), Olivia Lucas (12906173), Charlotte Milner-Watts (12906287), Gordon Stamp (55542), Zayd Tippu (9622118), Ultan McDermott (213251), Ruby Stewart (12906296), Crispin Hiley (8500467), Olaf Ansorge (255880), Simone Zaccaria (4030334), Alexander W Wyatt (12906392), Zoe Rhodes (12906137), Anuradha Jayaram (7130900), Daniel Hochhauser (1920799), James Black (10276906), Emilia Lim (4046039), Chris Abbosh (10504001), Gerhardt Attard (120990), Eleanor Carlyle (11306169), Max Emmerich (12906254), Tariq Enver (1653), Laura Farrelly (7049078), Joanne Webb (12906356), Hayley Bridger (12906383), Sarah Rudman (707335), Orsetta Quaini (12906107), Sonya Hessey (12906119), Dhruva Biswas (10504007), Kevin Litchfield (8318559), Fiona Blackhall (594412), Kristiana Grigoriadis (12789846), Stefano Lise (57498), Scott Tagawa (12906116), Scott Shepherd (12906248), Ian Proctor (9360179), Claudia Peinador Marin (12906227), Charlotte Lewis (12906263), Denise Kelly (53239), Allan Hackshaw (4355305), Supreet Bola (12906200), Seng Kuong Ung (12906221), Benny Chain (133611), Clare Puttick (10503995), Babu Naidu (594446), Rachel Rosenthal (3437186), Peter Cockcroft (10798491), Chris Bailey (1920991), Andrew Tutt (245167) +250 morecore +1 more sourcePartial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti +4 morewiley +1 more sourcePredictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo +7 morewiley +1 more sourceKeragaman Alel Gadung Liar (Dioscorea bulbifera L.) di Sumatera Barat
Makara Seri Sains, 2007 The variety of six enzymes locus on three populations of Dioscorea bulbifera was revealed using both starch and polyacrilamide gel electrophoresis. Present study showed three polymorphic loci has each 2 alleles with nine total numbers of alleles for all ...Mansyurdin, Tesri Maidelizadoaj NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim +11 morewiley +1 more sourceThe C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata +19 morewiley +1 more source
