Results 91 to 100 of about 818,935 (300)

Comportamiento de los alelos HLA-DQB1*02 y HLA-DQB1*03 en pacientes con diagnóstico presuntivo de enfermedad celíaca Behavior of HLA-DQB1*02 and HLA-DQB1*03 alleles in patients with a presumptive diagnosis of celiac disease

open access: yesRevista Cubana de Medicina, 2011
La enfermedad celíaca (EC) es autoinmune y se observa en individuos genéticamente predispuestos, se caracteriza por la intolerancia a determinadas proteínas llamadas gluten (gliadinas y gluteínas) que se encuentran en el trigo, el centeno y la cebada. Se
Sylvia Torres Odio   +8 more
doaj  

GENOTYPIC STRUCTURE OF THE BUUBEI AND ZABAIKALSKAYA BREED SHEEP ACCORDING TO THE GENES GDF9, CAST, KRT1.2, KAP1.3 AND THEIR RELATIONSHIP WITH PRODUCTIVITY

open access: yesSiberian Journal of Life Sciences and Agriculture
The purpose of this study is to identify the polymorphism of the GDF9, CAST, KRT1.2, KAP1.3 genes and to study their influence on the live weight and wool productivity of the Zabaikalskaya fine-wool breed and coarse-wooled Buubei sheep.
Galina M. Goncharenko   +5 more
doaj   +1 more source

Preface: Allele Mining for Genomic Designing of Oilseed Crops [PDF]

open access: yes
This book deliberates on the concept, strategies, tools, and techniques of allele mining in oilseed crops and its application potential in genome elucidation and improvement, including studying allele evolution, discovery of superior alleles, discerning ...
Puppala, N, Pandey, M K, Kole, C
core   +1 more source

Mixed allele malaria vaccines: Host protection and within-host selection [PDF]

open access: yes, 2008
Malaria parasites are frequently polymorphic at the antigenic tat-gets of many candidate vaccines, presumably as a consequence of selection pressure from protective immune responses.
Anders, Robin F.   +5 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Genetic differences between Mestizo populations of Bolivia and Peru

open access: yesBulletin de l'Institut Français d'Études Andines, 2003
Data on the genetic background of Peruvian and Bolivian populations is still scarce. Studies have shown that mestizos (i.e. mixed, but of predominantly Native American ancestry) present several HLA alleles originally described in genetically isolated ...
Jorge Cervantes
doaj   +1 more source

Allele Mining for Molecular Breeding in Potato [PDF]

open access: yes
Potato has great genetic diversity that has been lost during the process of domestication. Due to this constraint, modern breeding programs rely on limited genetic resources for the improvement of potato.
Yavuz, Caner   +2 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

EcoTILLING-based association mapping efficiently delineates functionally relevant natural allelic variants of candidate genes governing agronomic traits in chickpea

open access: yesFrontiers in Plant Science, 2016
The large-scale mining and high-throughput genotyping of novel gene-based allelic variants in natural mapping population are essential for association mapping to identify functionally relevant molecular tags governing useful agronomic traits in chickpea.
Deepak eBajaj   +7 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

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