Results 111 to 120 of about 655,342 (154)
Some of the next articles are maybe not open access.
2014
Methods used to understand the function of a gene/protein are one of the hallmarks of modern molecular genetics. The ability to genetically manipulate bacteria has become a fundamental tool in studying these organisms and while basic cloning has become a routine task in molecular biology laboratories, generating directed mutations can be a daunting ...
McKenzie K, Lehman +2 more
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Methods used to understand the function of a gene/protein are one of the hallmarks of modern molecular genetics. The ability to genetically manipulate bacteria has become a fundamental tool in studying these organisms and while basic cloning has become a routine task in molecular biology laboratories, generating directed mutations can be a daunting ...
McKenzie K, Lehman +2 more
openaire +2 more sources
2011
Methods of estimating allele frequencies from data on unrelated and related individuals are described in this chapter. For samples of unrelated individuals with simple codominant markers, the natural estimator of allele frequencies can be used. For genetic data on related individuals, maximum likelihood estimation (MLE) can be applied to compute allele
Indra, Adrianto, Courtney, Montgomery
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Methods of estimating allele frequencies from data on unrelated and related individuals are described in this chapter. For samples of unrelated individuals with simple codominant markers, the natural estimator of allele frequencies can be used. For genetic data on related individuals, maximum likelihood estimation (MLE) can be applied to compute allele
Indra, Adrianto, Courtney, Montgomery
openaire +3 more sources
Asymptotics of the allele frequency spectrum and the number of alleles
Journal of Applied ProbabilityAbstractWe derive large-sample and other limiting distributions of components of the allele frequency spectrum vector, $\mathbf{M}_n$ , joint with the number of alleles, $K_n$ , from a sample of n genes. Models analysed include those constructed from gamma and $\alpha$ -stable subordinators by Kingman (thus including the Ewens model), the two ...
Ross Maller, Soudabeh Shemehsavar
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On the Genealogy of a Rare Allele
Theoretical Population Biology, 1997The gene genealogy is derived for a rare allele that is descended from a mutant ancestor that arose at a fixed time in the past. Following Thompson (1976, Amer. J. Human Genet. 28, 442-452), the fractional linear branching process is used as a model of the demography of a rare allele.
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Perspectives on Allele-Specific Expression
Annual Review of Biomedical Data Science, 2021Cathal Seoighe
exaly
KRAS mutant allele-specific imbalance in lung adenocarcinoma
Modern Pathology, 2011Simion Chiosea +2 more
exaly