Results 101 to 110 of about 876,901 (295)
Multipoint linkage disequilibrium mapping using multilocus allele frequency data
, 2005 This paper describes a likelihood based fine scale linkage disequilibrium mapping method for estimating the position of a disease predisposing gene relative to a battery of typed marker loci. The method uses multilocus allele frequency data from a sample
Johnson, T.
core +1 more source
Reduced hippocampal volume in healthy young ApoE4 carriers: an MRI study. [PDF]
, 2012 The E4 allele of the ApoE gene has consistently been shown to be related to an increased risk of Alzheimer's disease (AD). The E4 allele is also associated with functional and structural grey matter (GM) changes in healthy young, middle-aged and older ...
Miller, Julia +26 more
core +3 more sources
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2004 Varios estudios han demostrado la asociación de los polimorfismos de la apolipoproteína E (APO-E) con la osteoporosis, especialmente, la APO-E 4. Para analizar los polimorfismos APOE e identificar la asociación con variables clínicas y sociales, se ...
Elsa Villarreal, Antonio Bermúdez
doaj +1 more source
Mixed allele malaria vaccines: Host protection and within-host selection [PDF]
, 2008 Malaria parasites are frequently polymorphic at the antigenic tat-gets of many candidate vaccines, presumably as a consequence of selection pressure from protective immune responses.
Anders, Robin F. +5 more
core +1 more source
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Генетическая структура коров черно-пестрой породы по лактопротеинам
Agricultural Science, 2020 Systematic genetic monitoring in populations allows to control the level of genetic diversity, to use the capabilities of marker selection, including the assessment of intra-breed differentiation, the formation of an optimal genealogical structure and ...
Татьяна ЛУПОЛОВА +2 more
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Allele Mining for Molecular Breeding in Potato [PDF]
Potato has great genetic diversity that has been lost during the process of domestication. Due to this constraint, modern breeding programs rely on limited genetic resources for the improvement of potato.
Yavuz, Caner +2 more
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
ABO Rhesus phenotypic and allelic frequencies in blood donors in Oran
Journal de la Faculté de Médecine d'Oran, 2017 Introduction - The objective of this study is to estimate the phenotypic and gene frequencies of the ABO and Rhesus (D) systems in blood donors in Oran.
Tahar Deba +4 more
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