Results 241 to 250 of about 880,277 (345)
The association of CGG repeat length and AGG interruption patterns on FMR1 alleles with female infertility. [PDF]
Xuanyou Z+6 more
europepmc +1 more source
Noninvasive and sensitive detection of tau protein dynamics across developmental stages and APOE genotypes remain a challenge in Alzheimer's disease (AD) research. This study reveals the dynamics of tau secretion in label‐free manner using surface‐enhanced Raman spectroscopy (SERS) and human cerebral organoids (hCOs). This study provides novel insights
Yongjae Jo+11 more
wiley +1 more source
Allelic Variations in Phenology Genes in Club Wheat (<i>Triticum compactum</i>) and Their Association with Heading Date. [PDF]
Mata B, Cabrera A.
europepmc +1 more source
HISTOCOMPATIBILITY GENES OF MICE VIII. THE ALLELES OF THE H-1 LOCUS
Ralph J. Graff, George D. Snell
openalex +1 more source
YTHDC1 Is Essential for Postnatal Liver Development and Homeostasis
This study identifies YTHDC1 as a key regulator of postnatal liver development and disease. Hepatocyte‐specific deletion of Ythdc1 impairs hepatocyte maturation, causing liver injury, contributing to nonalcoholic steatohepatitis and hepatocellular carcinoma.
Xinzhi Li+8 more
wiley +1 more source
Crop wild relative populations of Beta vulgaris as source for genome-wide association mapping of complex traits. [PDF]
Bertram L, Kopisch-Obuch F, Frisch M.
europepmc +1 more source
Base editing enables precise nucleotide substitutions but limited by bystander editing. This study engineers plant base editors by fusing optimized TadA variants with PAM‐flexible SpRY nickase, enabling A‐to‐G, C‐to‐T, and dual‐base conversions in a highly condensed window (≤3 nucleotides). Additionally, TadDBE (TadA Dual‐Base Editor)‐mediated directed
Kangli Sun+14 more
wiley +1 more source
<i>FMR1</i> Allelic Complexity and IVF Fertilization Success: Limitations and Future Perspectives. [PDF]
Rodrigues B+6 more
europepmc +1 more source
This study synthesized a personalized neoantigen vaccine (Neo‐CRCVAS) and combined it with regorafenib, termed RegoNeo. This combination therapy significantly enhanced antitumor efficacy and promoted long‐term tumor‐specific immune memory in microsatellite stable colorectal cancer liver metastasis (MSS‐CRLM) models by increasing neoantigen‐specific ...
Hengkai Chen+11 more
wiley +1 more source