Results 241 to 250 of about 870,271 (337)

Tulp3 quantitative alleles titrate requirements for viability, brain development, and kidney homeostasis but do not suppress Zfp423 mutations in mice. [PDF]

PLoS Genet
McCoy CA, Concepcion D, Mezody MG, Lara RZ, Deshpande O, Liang C, Long R, Hamilton BA.   +7 more
europepmc   +1 more source

Autologous Organoid‐T Cell Co‐Culture Platform for Modeling of Immune‐Mediated Drug‐Induced Liver Injury

Advanced Science, EarlyView.
A matrix‐free human liver organoid–T cell co‐culture platform enables modeling of immune‐mediated drug‐induced liver injury (iDILI). Using flucloxacillin and patient‐matched cells, this system recapitulates HLA‐B*57:01–restricted CD8⁺ T cell activation and hepatocyte damage.
Fadoua El Abdellaoui Soussi, Michael Brusilovsky, Emma Buck, W Clark Bacon, Sina Dadgar, Aaron Fullerton, Victoria Marsh Durban, Riccardo Barrile, Michael A. Helmrath, Takanori Takebe, Adrian Roth, Magdalena Kasendra   +11 more
wiley   +1 more source

Risk and Association of Specific HLA Alleles With Nintedanib-Induced Gastrointestinal Adverse Reactions: A Discovery Study in an Italian Population. [PDF]

Clin Transl Sci
Mocci S, Littera R, Deidda S, Perra A, Floris M, Giglio S.   +5 more
europepmc   +1 more source

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

Advanced Science, EarlyView.
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang, Youtao Wang, Cong Sun, Tao Liu, Zengfeng Wu, Lipeng Chen, Lina Chen, Penglin Li, Zhengkang Li, Cangui Zhang, Bingyun Lu, Ye Chen, Bing Gu, Qian Zhong, Xin Wei Wang, Mu‐Sheng Zeng, Jinping Liu   +16 more
wiley   +1 more source

Revisiting guidance on population sampling for highly polymorphic STR loci. [PDF]

Forensic Sci Int Genet
Aalbers SE, Gettings KB.
europepmc   +1 more source

EFFECTS OF PRETREATMENT WITH X RAYS ON PARAMUTABILITY OR PARAMUTAGENICITY OF CERTAIN R ALLELES IN MAIZE

, 1969
K Shih
openalex   +2 more sources

THE MAINTENANCE OF ALLELES BY MUTATION [PDF]

Genetics, 1964
openaire   +2 more sources

Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma

Advanced Science, EarlyView.
Lung squamous cell cancer (LUSC) is deadly due to lack of good treatments. Here, multiomics techniques are applied to LUSC tumors and find thousands of cancer‐specific enhancers controlling key genes. Interestingly, the gene PTPRZ1 is identified as a critical oncogene driven by the LUSC‐acquired enhancers. PTPRZ1 is activated by MDK, fueling cancer via
Yong‐Qiang Ning, Jie Wang, Yihui Zhang, Hongrui Li, Zenan Jiang, Xinyu Su, Xiao Yang, Xiaoxuan Wu, Bing Wei, Jianmin Ying, Jian Yan, Wenbin Li   +11 more
wiley   +1 more source

Characterization and evolution of MHC II genes in the European eel (Anguilla anguilla) [PDF]

, 2013
Bracamonte, Seraina E.
core  

The almond Sf allele: an allele in question

, 2011
Socias i Company, Rafel, Kodad, Ossama, Fernández i Martí, Angel V., Alonso Segura, José Manuel   +3 more
openaire   +1 more source