Results 41 to 50 of about 1,221,818 (402)
Maize lethal necrosis (MLN), resulting from co-infection by maize chlorotic mottle virus (MCMV) and sugarcane mosaic virus (SCMV) can cause up to 100% yield losses in maize in Africa under serious disease conditions.
Luka A. O. Awata+12 more
doaj +1 more source
Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh+5 more
wiley +1 more source
Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression
Ribosomal RNA sequence variants are conserved, exhibit tissue-specific expression, and are found in actively translating ribosomes. The ribosome, the integration point for protein synthesis in the cell, is conventionally considered a homogeneous ...
Matthew M. Parks+10 more
semanticscholar +1 more source
Fitness costs associated with evolved herbicide resistance alleles in plants [PDF]
Predictions based on evolutionary theory suggest that the adaptive value of evolved herbicide resistance alleles may be compromised by the existence of fitness costs.
Neve, Paul+2 more
core +1 more source
COVID‐19 and the risk of Alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosis
Abstract Background The coronavirus disease 2019 (COVID‐19) pandemic has had an unprecedented impact on the healthcare system, economy, and society. Studies have reported that COVID‐19 may cause various neurologic symptoms, including cognitive impairment.
Hanyu Zhang, Zengyuan Zhou
wiley +1 more source
Congenital heart defects are anomalies that are becoming more and more frequent every year. Their specific weight is the highest among all the defects and malformations in fetus.
A.V. Shabaldin+4 more
doaj +1 more source
Mosaicism in Vacuolating Cytotoxin Alleles of Helicobacter pylori
Approximately 50% of Helicobacter pylori strains produce a cytotoxin, encoded by vacA, that induces vacuolation of eukaryotic cells. Analysis of a clinically isolated tox strain (Tx30a) indicated secretion of a 93-kDa product from a 3933-base pair vacA ...
J. Atherton+5 more
semanticscholar +1 more source
Reliability assessment of null allele detection: inconsistencies between and within different methods [PDF]
Microsatellite loci are widely used in population genetic studies, but the presence of null alleles may lead to biased results. Here we assessed five methods that indirectly detect null alleles, and found large inconsistencies among them.
Avise+31 more
core +1 more source
Abstract Objectives Early‐ and late‐onset Alzheimer's disease (EOAD and LOAD) share the same neuropathological traits but show distinct cognitive features. We aimed to explore baseline and longitudinal outcomes of global and domain‐specific cognitive function in a well characterized cohort of patients with a biomarker‐based diagnosis.
Adrià Tort‐Merino+16 more
wiley +1 more source
Risk alleles for multiple sclerosis identified by a genomewide study.
BACKGROUND Multiple sclerosis has a clinically significant heritable component. We conducted a genomewide association study to identify alleles associated with the risk of multiple sclerosis. METHODS We used DNA microarray technology to identify common
D. Hafler+18 more
semanticscholar +1 more source