Results 41 to 50 of about 870,271 (337)

Polymorphisms in the genes of citohrom oxidase P450 2D6 (CYP2D6), paraoxonase 1 (PON1) and apolipoproteine E (APOE) as risk factors for Parkinson's disease [PDF]

Vojnosanitetski Pregled, 2007
Background/Aim. The presence of Parkinson's disease (PD) among the members of a family is a clear indication of the significance of genetics in its development.
Đurić Gordana, Svetel Marina, Illarioškin Nikolaevič Sergej, Dragađević Nataša, Gavrilović Jelena, Kostić Vladimir S.   +5 more
doaj   +1 more source

HLA and HIV Infection Progression: Application of the Minimum Description Length Principle to Statistical Genetics

, 2005
The minimum description length (MDL) principle states that the best model to account for some data minimizes the sum of the lengths, in bits, of the descriptions of the model and the residual error.
Erlich, Henry A., Hraber, Peter T., Kepler, Thomas B., Korber, Bette T., Trachtenberg, Elizabeth A., Wolinsky, Steven   +5 more
core   +1 more source

Limited antigenic diversity of Plasmodium falciparum apical membrane antigen 1 supports the development of effective multi-allele vaccines [PDF]

, 2014
BackgroundPolymorphism in antigens is a common mechanism for immune evasion used by many important pathogens, and presents major challenges in vaccine development.
Anders, Robin F., Barry, Alyssa E., Beeson, James G., Cross, Nadia J., Drew, Damien R., Dutta, Sheetij, Elliott, Salenna R., Hodder, Anthony N., Marsh, Kevin, Mueller, Ivo, Mugyenyi, Cleopatra K., Osier, Faith, Richards, Jack S., Senn, Nicolas, Siba, Peter M., Stanisic, Danielle I., Terheggen, Ulrich   +16 more
core   +1 more source

IDENTIFICATION OF ROTAVIRUS I- AND E-GENOTYPES BY MULTIPLEX PCR METHOD

Вопросы вирусологии, 2019
Introduction. In recent years the presence of reassortant rotavirus strains is increasingly mentioned in the world due to the application of the full-genome based classification system.
T. A. Sashina, O. V. Morozova, N. V. Epifanova, N. A. Novikova   +3 more
doaj   +1 more source

Polymorphisms associated with the number of live-born piglets in sows infected with the PRRS virus in southern Sonora Mexico

Revista Mexicana de Ciencias Pecuarias, 2020
The porcine reproductive and respiratory syndrome (PRRS) is a viral disease that decreases the reproductive performance in breeding sows and leads to economic losses to the swine industry.
Carlos Martín Aguilar-Trejo, Guillermo Luna-Nevárez, Javier Rolando Reyna-Granados, Ricardo Zamorano-Algandar, Javier Alonso Romo-Rubio, Miguel Ángel Sánchez-Castro, R. Mark Enns, Scott E. Speidel, Milton G. Thomas, Pablo Luna-Nevárez   +9 more
doaj   +1 more source

Non-Classical Congenital Adrenal Hyperplasia-Causing Alleles in Adolescent Girls with PCOS and in Risk Group for PCOS Development

Diagnostics, 2021
Background: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women. Depending on the diagnostic criteria applied, it occurs in up to 16.6% of the general female population. Congenital adrenal hyperplasia includes a group of autosomal
Lasma Lidaka, Laine Bekere, Gunta Lazdane, Iveta Dzivite-Krisane, Anda Kivite-Urtane, Linda Gailite   +5 more
doaj   +1 more source

Association of Chlamydia pneumoniae with coronary artery disease and its progression is dependent on the modifying effect of mannose-binding lectin [PDF]

, 2002
Background— The possible association between coronary artery disease (CAD) and Chlamydia pneumoniae (C pneumoniae) infection is controversial. On the basis of the recent suggestion that mannose-binding lectin (MBL) variant alleles are related to an ...
Burián, Katalin, Duba, Jenő, Endrész, Valéria, Füst, György, Garred, Peter, Gönczöl, Éva, Karádi, István, Madsen, Hans O., Prohászka, Zoltán, Romics, László, Rugonfalvi-Kiss, Szabolcs   +10 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

INNA N. GOLUBOVSKAYA AS THE FOUNDER OF A UNIQUE COLLECTION OF MEIOTIC GENE MUTATIONS IN MAIZE AND A TALENTED RESEARCHER OF THE PROBLEM OF MEIOSIS GENETIC CONTROL

Труды по прикладной ботанике, генетике и селекции, 2018
Over 40 years, Inna Nikitichna Golubovskaya studied the fundamental problem of genetic control of meiosis, using meiosis in Zea mays as the model. She discovered more than half of 50 genes and gene alleles controlling meiosis in maize anthers and ovules,
Yu. F. Bogdanov
doaj   +1 more source

Purine alkaloids in tea plants: component, biosynthetic mechanism and genetic variation

Beverage Plant Research, 2022
The purine alkaloids, including caffeine, theobromine, and theacrine, are one of the most important quality and functional components of tea plants and commercial teas.
Shuran Zhang, Jiqiang Jin, Jiedan Chen, Sezai Ercisli, Liang Chen   +4 more
doaj   +1 more source