Results 61 to 70 of about 889,593 (339)

The Effect of Recombination on the Speed of Evolution [PDF]

open access: yes, 2019
It has been a puzzling question why some organisms reproduce sexually. Fisher and Muller hypothesized that reproducing by sex can speed up the evolution.
Udomchatpitak, Nantawat
core   +1 more source

Pleiotropy of FRIGIDA enhances the potential for multivariate adaptation. [PDF]

open access: yes, 2013
An evolutionary response to selection requires genetic variation; however, even if it exists, then the genetic details of the variation can constrain adaptation.
Easlon, Hsien M   +9 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

HLA diversity in the Russian population assessed by next generation sequencing

open access: yesМедицинская иммунология, 2021
Next generation sequencing is used to determine full-length sequences of HLA genes at the 4-field (allelic) resolution. The study was aimed at determining frequency and diversity of HLA alleles in a cohort of blood donors from the Registry of the ...
E. G. Khamaganova   +5 more
doaj   +1 more source

HLA and HIV Infection Progression: Application of the Minimum Description Length Principle to Statistical Genetics

open access: yes, 2005
The minimum description length (MDL) principle states that the best model to account for some data minimizes the sum of the lengths, in bits, of the descriptions of the model and the residual error.
Erlich, Henry A.   +5 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Standardized SSR allele naming and binning among projects

open access: yesBioTechniques, 2010
Simple sequence repeats (SSRs) have proven to be extremely valuable DNA markers for genetic mapping and population genetic analyses. However, data collected across laboratories or even within laboratories are difficult to combine due to challenges in ...
Dennis L. Deemer, C. Dana Nelson
doaj   +1 more source

The effect of sheltered load on reproduction in Solanum carolinense, a species with variable self-incompatibility [PDF]

open access: yes, 2009
In previous studies, we have investigated the strength of self-incompatibility (SI) in Solanum carolinense, a highly successful weed with a fully functional SI system that inhabits early successional and other disturbed habitats.
Keser, L.H.   +2 more
core   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Genetic variability for yield and related traits among wild accessions of cowpea and cross-compatibility with cultivated accessions

open access: yesAgricultura Tropica et Subtropica
Cowpea is an important legume, and its wild relatives could be reliable sources of favorable alleles for genetic diversity and improvement of important traits.
Olayiwola Richard Oluseyi   +3 more
doaj   +1 more source

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