Results 11 to 20 of about 7,354,999 (259)

Allergen Specific Immunotherapy

Güncel Pediatri, 2015
Allergen specific immunotherapy (SIT) is the only treatment that can provide a cure for allergic disorders. This treatment is based on development of immune tolerance by exposure to allergen in repetitive and increasing doses. It is tertiary to avoidance of allergen and pharmacotherapy.
ÇEKİÇ, ŞÜKRÜ, SAPAN, NİHAT
openaire   +5 more sources

Diverse Mechanisms of Allergen Specific Immunotherapy

RUDN Journal of Medicine, 2019
Allergen immunotherapy (AIT) is widely used to establish a tolerant immune response and it is currently the only disease modifying treatment. There are different routes to administer the allergen, including subcutaneous, sublingual, intralymphatic ...
Lacin Cevhertas, Mübeccel Akdis
doaj   +2 more sources

Successful Allergen-Specific Immunotherapy: Induction of Unresponsiveness by 'Vaccination'. [PDF]

Vaccines (Basel), 2023
The mechanisms of action of allergen-specific immunotherapy (AIT) are often referred to as the induction of 'tolerance'. However, immunological 'tolerance' is defined as an alteration in the function or composition of immune cells.
Bachmann MF, Vogel M, Speiser DE.
europepmc   +3 more sources

A Comprehensive Overview of Allergen-specific Immunotherapy Types, Recombinant and Natural Extract Allergens in the Diagnosis and Treatment of Allergies

Iranian Journal of Allergy, Asthma and Immunology, 2022
Allergen-specific immunotherapy (AIT) involves administering allergen extracts. It is used to desensitize allergic patients. Herbal allergen extracts that are optimum in efficacy and fewest in side effects are still challenging to produce.
Soheila Asoudeh Moghanloo, Mohsen Forouzanfar, Mojtaba Jafarinia, Mohammad Reza Fazlollahi, Gholam Ali Kardar   +4 more
doaj   +1 more source

Specific IgE and IgG4 Profiles of House Dust Mite Components in Allergen-Specific Immunotherapy

Frontiers in Immunology, 2022
BackgroundAllergen immunotherapy (AIT) can induce immune tolerance to allergens by activating multiple mechanisms, including promoting IgG4 synthesis and blunting IgE production.
Lin Yang, Yaqi Yang, Qingxiu Xu, Wei Zhang, Qing Jiang, Wenjing Li, Yin Wang, Dongxia Ma, Xiaomin Lin, Baoqing Sun, Rongfei Zhu   +10 more
doaj   +1 more source

Mechanisms of allergen-specific immunotherapy and allergen tolerance

Allergology International, 2020
Allergen-specific immunotherapy (AIT) is the mainstay treatment for the cure of allergic disorders, with depicted efficacy and safety by several trials and meta-analysis.
Umut C. Kucuksezer, Cevdet Ozdemir, Lacin Cevhertas, Ismail Ogulur, Mubeccel Akdis, Cezmi A. Akdis   +5 more
doaj   +1 more source

Preclinical evaluation of alternatives to oral immunotherapy for food allergies

Frontiers in Allergy, 2023
The increasing food allergy incidence has led to significant interest in developing therapies for allergic diseases. Oral allergen-specific immunotherapy (OIT) is a recently FDA-approved therapeutic to treat peanut allergies.
Brandi T. Johnson-Weaver
doaj   +1 more source

A Review of Allergy and Allergen Specific Immunotherapy

Iranian Journal of Allergy, Asthma and Immunology, 2011
Since 20th  century, when allergy was defined, an ongoing attempt for discovering the mechanisms underlying it and its treatment began. Defining allergens as well as cells such as regulatory T-cells and characterizing the antibodies involved in the ...
Katayoon Bidad, Mohammad Hossein Nicknam, Reza Farid   +2 more
doaj   +2 more sources

A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis [PDF]

, 2013
© Queen’s Printer and Controller of HMSO 2013Severe allergic rhinitis uncontrolled by conventional medication can substantially affect quality of life. Immunotherapy involves administering increasing doses of a specific allergen, with the aim of reducing
B Kaambwa, P Barton, Barton, P, J Dretzke, Kaambwa, B, A Huissoon, Novielli, N, C Meads, A Meadows, A Fry-Smith, Dretzke, J, Huissoon, A, N Novielli, Fry-Smith, A, Meads, C, Meadows, A   +15 more
core   +1 more source

Tryptophan metabolite-regulated Treg responses contribute to attenuation of airway inflammation during specific immunotherapy in a mouse asthma model

Human Vaccines & Immunotherapeutics, 2020
In allergen-specific immunotherapy for asthma, antigens attached to dendritic cells increase the tryptophan metabolism in these cells and alter the Th17/Treg balance in the airways.
Qi Hu, Ling Jin, Jing Zeng, Jinyu Wang, Shimin Zhong, Wenting Fan, Wei Liao   +6 more
doaj   +1 more source