Results 51 to 60 of about 7,354,999 (259)
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Background The prevalence of allergic rhinitis (AR) and asthma (AS) comorbidity (AR + AS) is increasing and is associated with severe allergic symptoms. The impact of cat dander sensitization on AR + AS remains unclear. Methods In this retrospective study, 1154 patients with AR alone and 213 patients with AR + AS were enrolled at the Third ...
Wei‐Hao Wang +5 more
wiley +1 more source
Personalized Surgery for Allergic Fungal Rhinosinusitis
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Background Allergic fungal rhinosinusitis (AFRS) frequently presents as unilateral or asymmetric disease. In cases with minimal disease on one side, the question remains as to the necessary extent of surgery. Objective To determine the relationship between symmetry and clinical characteristics in AFRS patients, with a focus on implications for
Erin E. Briggs +7 more
wiley +1 more source
Zdorovʹe Rebenka, 2014 The article presents the results of a study on the clinical and immunological course of bronchial asthma, depending on its phenotype and duration of specific immunotherapy.
S.M. Nedelska, N.M. Taran
doaj +1 more source
Allergy, EarlyView.This study established a microarray containing a representative panel of purified Blo t and Der p allergens for the identification of patients sensitised to Blo t and/or Der p. Results indicate that the microarray based on Blo t and Der p allergens is a useful tool for the identification of Blo t‐ and/or Der p‐sensitised patients. The microarray may be
Nishelle Dsouza +16 more
wiley +1 more source
Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells
Allergy, EarlyView.We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller +16 more
wiley +1 more source
Novel Approaches to Allergen Immunotherapy for Respiratory Allergies
PharmaceuticalsAllergen immunotherapy (AIT) remains the cornerstone for managing respiratory allergies, offering long-term symptom relief, disease modification, and prevention of disease progression.
Mongkol Lao-Araya
doaj +1 more source
Scientific Reports, 2017 House dust mite (HDM) allergy is a predominant cause for perennial allergic rhinitis (AR) in Europe. We recently reported that circulating erythrocyte numbers decrease after airway allergen challenge in a murine asthma model and in grass-pollen ...
Galateja Jordakieva +6 more
doaj +1 more source
Clinical and Translational Allergy, 2012 Allergy today is a public health concern of pandemic proportions, affecting more than 150 million people in Europe alone. In view of epidemiological trends, the European Academy of Allergy and Clinical Immunology (EAACI) predicts that within the next few
Calderon Moises A +45 more
doaj +1 more source
Immune Mechanisms of Allergen-Specific Immunotherapy [PDF]
The Open Allergy Journal, 2012 Allergen immunotherapy (AIT) has the exclusive ability to modify the natural history of allergy and to maintain its clinical efficacy also after stopping the treatment. This occurs because of the AIT mechanism of action, mainly consisting in a specific induction of tolerance to the causative allergen. Such tolerance takes place as a result of a complex
Yacoub, Mona-Rita +3 more
openaire +2 more sources
, 2004 Although several studies support the efficacy of specific immunotherapy in allergic asthma, its benefit compared with that of standardized pharmacologic intervention remains unknown.
PIACENTINI, Giorgio +5 more
core +1 more source