Results 281 to 290 of about 94,577 (314)
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Clinical Reviews in Allergy & Immunology, 2001
What makes an antigen an allergen? This question has been at the core of much research regarding the basic mechanisms of allergy as well as the development of diagnostic and therapeutic allergen products. Great strides have been made since Kjell Aas asked this question in his classic review in Allergy (1), but we appear no closer to the answer.
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What makes an antigen an allergen? This question has been at the core of much research regarding the basic mechanisms of allergy as well as the development of diagnostic and therapeutic allergen products. Great strides have been made since Kjell Aas asked this question in his classic review in Allergy (1), but we appear no closer to the answer.
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Immunology and Allergy Clinics of North America, 2005
Exposure to allergens is a trigger for symptoms in sensitized individuals with asthma. This is especially true for allergens primarily found indoors but can be true for outdoor allergens with sufficiently high exposure. The role of allergens in attacks can be subtle in that they provide the underlying inflammation necessary for other nonspecific agents
Elizabeth A, Erwin +1 more
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Exposure to allergens is a trigger for symptoms in sensitized individuals with asthma. This is especially true for allergens primarily found indoors but can be true for outdoor allergens with sufficiently high exposure. The role of allergens in attacks can be subtle in that they provide the underlying inflammation necessary for other nonspecific agents
Elizabeth A, Erwin +1 more
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Primary Care: Clinics in Office Practice, 1987
The environment contains a huge array of allergens, primarily proteins or glycoproteins, to which the atopic individual may become sensitized. In situations of high exposure and highly reactive substances, even nonatopic individuals may develop allergic antibodies.
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The environment contains a huge array of allergens, primarily proteins or glycoproteins, to which the atopic individual may become sensitized. In situations of high exposure and highly reactive substances, even nonatopic individuals may develop allergic antibodies.
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1998
Allergen exposure is a risk factor for sensitisation, prevalence and severity of allergic disease. Effective allergen avoidance strategies have been devised. The cost-benefit in public health terms should be established by prospective controlled studies that are under way around the world.
Custovic, A, Woodcock, A.
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Allergen exposure is a risk factor for sensitisation, prevalence and severity of allergic disease. Effective allergen avoidance strategies have been devised. The cost-benefit in public health terms should be established by prospective controlled studies that are under way around the world.
Custovic, A, Woodcock, A.
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Allergen databases and allergen semantics
Regulatory Toxicology and Pharmacology, 2009The efficacy of any specific bioinformatic analysis of the potential allergenicity of new food proteins depends directly on the nature and content of the databases that are used in the analysis. A number of different allergen-related databases have been developed, each designed to meet a different need.
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Factors Influencing the Allergenicity and Adjuvanticity of Allergens
Immunotherapy, 2011IgE-mediated allergic disorders affect up to 25% of the population in industrialized countries and result in a Th2-polarized immune response to innocuous environmental proteins, so-called allergens. Among a large number of proteins to which humans are exposed to, only a minute fraction are allergens.
Stephan Deifl, Barbara Bohle
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2005
Allergy affects more than 25% of Western populations (1) and is estimated to be the sixth leading cause of chronic disease in the United States and Western Europe. The complexity of the condition is such that hundreds of common allergens have been described, and in order to maximize diagnostic efficiency there is an urgent clinical requirement for ...
Bacarese Hamilton T. +3 more
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Allergy affects more than 25% of Western populations (1) and is estimated to be the sixth leading cause of chronic disease in the United States and Western Europe. The complexity of the condition is such that hundreds of common allergens have been described, and in order to maximize diagnostic efficiency there is an urgent clinical requirement for ...
Bacarese Hamilton T. +3 more
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Journal of Allergy and Clinical Immunology, 1994
This is a revision of the allergen nomenclature system which was proposed in 1986. The nomenclature is for allergens which induce IgE-mediated allergy in humans. A table of allergens with known partial or complete sequences as of December 1993 is given.
Hoffman D +5 more
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This is a revision of the allergen nomenclature system which was proposed in 1986. The nomenclature is for allergens which induce IgE-mediated allergy in humans. A table of allergens with known partial or complete sequences as of December 1993 is given.
Hoffman D +5 more
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Journal of Allergy and Clinical Immunology, 2009
The question "What makes an allergen an allergen?" has puzzled generations of researchers, and we still do not have a conclusive answer. Despite increasing knowledge about the molecular and functional characteristics of allergens that have been identified, we still do not fully understand why some proteins are clinically relevant allergens and most are
Traidl-Hoffmann, Claudia +2 more
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The question "What makes an allergen an allergen?" has puzzled generations of researchers, and we still do not have a conclusive answer. Despite increasing knowledge about the molecular and functional characteristics of allergens that have been identified, we still do not fully understand why some proteins are clinically relevant allergens and most are
Traidl-Hoffmann, Claudia +2 more
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Cockroach Allergens: Function, Structure and Allergenicity
Protein & Peptide Letters, 2007Cockroach allergy is a widespread health problem in the world, associated with the development of asthma. The German and American cockroach species are important producers of a wide variety of allergens. Knowledge of their structure and function contributes to understand their role in allergy and to design tools for diagnosis and immunotherapy.
Lisa D. Vailes +4 more
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