Results 281 to 290 of about 177,465 (363)
Economic Impact of Allergic Diseases and Asthma—The HEAD Pan‐European Registry
Allergy, EarlyView.This registry‐based study demonstrates the substantial economic burden of allergic diseases across Europe with a high degree of heterogeneity between countries. Treatments and specialist visits are the primary drivers of healthcare costs. Asthma poses the highest disease burden.Ioana Agache, Maria Torres, Ibon Eguiluz‐Gracia, Elena Bradatan, Kamal El Abd, Maria Beatrice Bilo, Federica Rivolta, Andrea Sangalli, Roxana Bumbacea, Selda Ali, Dario Antolin, Águeda Concepción Lario Cuenda, Vicente Albéndiz, Maria Miguel Oliveira, Paulo Jorge Nogueira, Loreto Carmona, HEAD Study Group, Audrey Courtois, Helene Simonis, Romain Nonis, Michel Crine, Christine Leon, Carine Sohy, Virgine Doyen, Andre Benedicte, Charles Pilette, Irina Kaidalina, Christophe Goubau, Katerina Absolonova, Ales Zlamal, Olga Zlamalova, Phillip Globig, Margitta Worm, Angelika Sasien, Mehrak Yoosefi Moridani, Federica Rivolta, Valentina Longo, Andrea Sangalli, Francesco Murzilli, Carmela Montera, Mario Lo Schiavo, Corina Bocsan, Corina Ureche, Cristian Budica, Diana Deleanu, Adriana Muntean, Agnes Sandor, Carmen Teodora Dorican, Camelia Berghea, Florin‐Dan Popescu, Irina Bucur, Mariana Vieru, Laia Ferré, Alicia Habernau, Agueda Larios, Jose Julio Laguna, Natalia Pérez Sánchez, Oscar Asensio, Roser Ayats, Helena Larramona, Beatriz Torres‐Pérez, Alica Barra‐Castro, Sergio Quevedo, Teresa Bracamonte, Manuel Diaz, Miguel Tortajada, Dah Tay Jang +66 morewiley +1 more sourceDupilumab Treatment Is Associated With Clinical Improvement and a Shift Toward a Health‐Associated Nasal Passage Microbiota in Diffuse Type 2 Chronic Rhinosinusitis
Allergy, EarlyView.This study investigates longitudinal effects of dupilumab on the nasal passage and gastrointestinal microbiota in patients with diffuse type 2 CRSwNP. CRSwNP patients show altered nasal microbiota composition compared to healthy individuals. Dupilumab treatment is associated with a shift of nasal microbiota in CRSwNP, with increasing beneficial genera (Fabio S. Ryser, Tomas Demeter, Judith Bergada Pijuan, Srikanth Mairpady Shambat, Catrin Brühlmann, Tina Mauthe, Markus Hilty, Michael B. Soyka, Urs C. Steiner, Silvio D. Brugger +9 morewiley +1 more sourceAerosol Measurements and Decadal Changes: The Role of Climatic Changes and How It Reflects in Respiratory Allergies and Asthma
Allergy, EarlyView.ABSTRACT
The causative agents of respiratory allergies are bioaerosols, such as house dust mite feces, pollen grains, and fungal spores. Climate change and urbanization are considered to lead to an increase in the load of allergenic bioaerosols due to impacts on plant phenophases and allergenicity. Continuous and efficient monitoring of the atmospheric Stelios Kazadzis, Illias Fountoulakis, Athanasios Damialis, Akriti Masoom, Kyriakoula Papachristopoulou, Stefanie Gilles, Martine Collaud Coen, Fiona Tummon, Benoît Crouzy, Bernard Clot, Yagiz Pat, Marie‐Charlotte Brüggen, Stephan Nyeki, Ioannis‐Panagiotis Raptis, Stavros Solomos, Antonis Gkikas, Anna Moustaka, Natalia Kouremeti, Cezmi A. Akdis +18 morewiley +1 more sourceGene–Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies
Allergy, EarlyView.Atopic eczema is a complex trait resulting from multiple genetic and environmental factors. This study investigated evidence for interaction between 24 established eczema genetic risk variants and 18 environmental factors. One variant‐environmental pair showed nominally significant interaction in discovery, replication and meta‐analyses: early‐life dog Marie Standl, Ashley Budu‐Aggrey, Luke J. Johnston, Martina S. Elias, S. Hasan Arshad, Peter Bager, Veronique Bataille, Helena Blakeway, Klaus Bønnelykke, Dorret Boomsma, Ben M. Brumpton, Mariona Bustamante Pineda, Archie Campbell, John A. Curtin, Anders Eliasen, João P. S. Fadista, Bjarke Feenstra, Trine Gerner, Carolina Medina‐Gomez, Sarah Grosche, Kristine B. Gutzkow, Anne‐Sofie Halling, Caroline Hayward, John Henderson, Esther Herrera‐Luis, John W. Holloway, Joukejan Hottenga, Jonathan O’B Hourihane, Chen Hu, Kristian Hveem, Amaia Irizar, Benedicte Jacquemi, Leon Jessen, Sara Kress, Ramesh J. Kurukulaaratchy, Susanne Lau, Sabrina Llop, Mari Løset, Ingo Marenholz, Dan Mason, Daniel L. McCartney, Mads Melbye, Erik Melén, Camelia Minica, Clare S. Murray, Tamar Nijsten, Luba M. Pardo, Suzanne Pasmans, Craig E. Pennell, Maria R. Rinnov, Gillian Santorelli, Tamara Schikowski, Darina Sheehan, Angela Simpson, Cilla Söderhäll, Laurent F. Thomas, Jacob P. Thyssen, Maties Torrent, Toos van Beijsterveldt, Alessia Visconti, Judith M. Vonk, Carol A. Wang, Cheng‐Jian Xu, Ali H. Ziyab, UK Translational Research Network in Dermatology, BIOMAP Consortium, Adnan Custovic, Paola Di Meglio, Liesbeth Duijts, Carsten Flohr, Alan D. Irvine, Gerard H. Koppelman, Young‐Ae Lee, Nick J. Reynolds, Catherine Smith, Sinéad M. Langan, Lavinia Paternoster, Sara J. Brown +77 morewiley +1 more source