Results 61 to 70 of about 180,280 (304)

Aeroallergen Sensitization and Clinical Characteristics of Subjects with Chronic Rhinitis in Chiang Mai, Thailand: A Twenty-Year Retrospective Study

Journal of Asthma and Allergy, 2021
Chaicharn Pothirat, Warawut Chaiwong Division of Pulmonary, Critical Care and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, ThailandCorrespondence: Chaicharn PothiratDivision of Pulmonary, Critical Care
Pothirat C, Chaiwong W
doaj  

Chitinases as Food Allergens

Molecules, 2019
Food allergies originate from adverse immune reactions to some food components. Ingestion of food allergens can cause effects of varying severity, from mild itching to severe anaphylaxis reactions.
Claudia Leoni, Mariateresa Volpicella, Maria C.G. Dileo, Bruno A.R. Gattulli, Luigi R. Ceci   +4 more
doaj   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

Allergen-specific Immunotherapy for Inhalant Allergens in Children

Current Pediatric Reviews, 2020
: Allergen-specific immunotherapy (AIT) for aeroallergens consists of the administration of standardized allergen extracts to patients with respiratory IgE-mediated diseases to the same allergen in order to achieve immune tolerance to the allergen and prevent the onset of symptoms.
Carlo, Caffarelli, Jessica, Cangemi, Carla, Mastrorilli, Arianna, Giannetti, Ricci, Giampaolo   +4 more
openaire   +3 more sources

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Domestic ventilation rates, indoor humidity and dust mite allergens : are our homes causing the asthma pandemic? [PDF]

, 2003
This paper is concerned with historical changes in domestic ventilation rates, relative humidity and the associated risk of house dust mite colonization.
McSharry, C, Morris, G, Jackson, J, Lawson, A, Howieson, S G, McKenzie, E   +5 more
core   +4 more sources

Development of a Sandwich ELISA to Measure Exposure to Occupational Cow Hair Allergens [PDF]

, 2011
Background: Cow hair and dander are important inducers of occupational allergies in cattle-exposed farmers. To estimate allergen exposure in farming environments, a sensitive enzyme immunoassay was developed to measure cow hair allergens.
Spickenheuer, Anne, Anne Spickenheuer, Ingrid Sander, Ilka Noss, Sander, Ingrid, Flagge, Angelika, Nowak, Dennis, Dennis Nowak, Joachim Sültz, Eva Zahradnik, Lydia Bruckmaier, Brüning, Thomas, Thomas Brüning, Zahradnik, Eva, Fleischer, Christina, Sültz, Joachim, Bruckmaier, Lydia, Monika Raulf-Heimsoth, Noss, Ilka, Raulf-Heimsoth, Monika, Rudolf Schierl, Schierl, Rudolf, Angelika Flagge, Christina Fleischer   +23 more
core   +1 more source

Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild‐to‐moderate asthma

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin and is approved for adolescents and adults with severe asthma. This analysis assessed pharmacokinetics (PK), pharmacodynamics and safety of tezepelumab up to 85 days postdose in adolescents and children.
Anna Lundahl, Jonathan Grigg, Lubna Abuqayyas, Piotr Kuna, Gillian Hunter, Beata Pawlikowska, Jacob Leander, Michael Levin, Atul Gupta, James Paton, Katharine C. Pike, Jane R. Parnes, Gun Almqvist, Stephanie L. Roseti, on behalf of the study investigators   +14 more
wiley   +1 more source

Evolution of standardization of therapeutic and diagnostic allergens produced in Russia

Аллергология и Иммунология в Педиатрии
Allergen-specific immunotherapy is based on the development of induced tolerance in patients. Natural extracts are most often used as therapeutic allergens worldwide.The article presents new approaches to biological standardization of subcutaneous ...
S. S. Masalskiy, E. I. Sakanyan, M. A. Yasnaya   +2 more
doaj   +1 more source

Interaction of Non-Specific Lipid-Transfer Proteins With Plant-Derived Lipids and Its Impact on Allergic Sensitization

Frontiers in Immunology, 2018
Non-specific lipid-transfer proteins (nsLTPs) represent a family of ubiquitous plant proteins belonging to the prolamin superfamily. nsLTPs are characterized by a globular α-helical structure stabilized by four disulfide bonds and a hydrophobic cavity ...
Stephan Scheurer, Stefan Schülke
doaj   +1 more source