A genome-wide association study for allergen component sensitizations identifies allergen component–specific and allergen protein group–specific associations [PDF]
Background: Allergic diseases are some of the most common diseases worldwide. Genome-wide association studies (GWASs) have been conducted to elucidate the genetic factors of allergic diseases.
Emiko Noguchi, Takako Nakamura
exaly +6 more sources
Profiles of Birch Allergen Component Sensitization and Its Association with Pollen Food Allergy Syndrome in Northern China [PDF]
Xiaoyan Wang,1,2 Lijia Chen,1 Jiaqi Ding,3 Hongtian Wang,1 Xueyan Wang1,2 1Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing, 100038, People’s Republic of China; 2Beijing Laboratory of Allergic Diseases, Beijing ...
Wang X, Chen L, Ding J, Wang H, Wang X
doaj +2 more sources
The high prevalence of Japanese cedar pollinosis in Japan is associated with a negative impact on the quality of life of patients, as well as significant loss of productivity among the workforce in early spring, thus representing a serious social problem.
Takashi Fujimura, Seiji Kawamoto
exaly +7 more sources
Concordance between crude extract and component allergens in a multiple allergen simultaneous test: a large-scale retrospective analysis [PDF]
ObjectivesMultiple allergen simultaneous tests (MAST) increasingly incorporate both crude extract and molecular component allergens for specific IgE testing.
Hyejin Ryu +3 more
doaj +2 more sources
Molecular Aspects of Allergen-Specific Immunotherapy in Patients with Seasonal Allergic Rhinitis
A systematic review and narrative synthesis of publications was undertaken to analyze the role of component-resolved diagnosis technology in identifying polysensitization for the provision of allergen-specific immunotherapy to patients with seasonal ...
Marina Izmailovich +2 more
exaly +3 more sources
Efficacy of house dust mite allergen immunotherapy in allergic rhinitis: a network meta-analysis based on component-resolved classification [PDF]
BackgroundHouse dust mite allergen immunotherapy (HDM-AIT) trials in allergic rhinitis show substantial efficacy heterogeneity, traditionally evaluated by administration route.
Shuo Guo +6 more
doaj +2 more sources
Background: Response patterns to allergen components among Japanese children have not been studied extensively. Objective: Our aim was to examine the differences in sensitization patterns at ages 5 years and 9 years to identify longitudinal changes in ...
Yukihiro Ohya, Limin Yang, Masami Narita
exaly +3 more sources
Human Allergy to Cats and Dogs: Molecular and Environmental Determinants, Diagnosis, and Precision Management [PDF]
Cat- and dog-derived allergenic proteins are important indoor exposure sources, but allergen exposure, IgE sensitization, and clinically manifest allergy are distinct biological and clinical states.
Jungwhan Chon +4 more
doaj +2 more sources
Early inhalant allergen sensitization at component level: an analysis in atopic Dutch children
BackgroundAllergic rhinitis is a common respiratory disease in children and sensitization to inhalant allergens plays a significant role in its development.
Nicolette J T Arends
exaly +3 more sources
A Fully Automated Chemiluminescent Immunoassay for Component-Resolved Diagnosis of Pollen Allergy: Validation of Six CHORUS CLIA Assays [PDF]
Background/Objectives: CHORUS CLIA “Allergy Components” is a novel line of fully automated assays designed to detect specific IgE directed against allergenic molecular components.
Helena Cerutti +7 more
doaj +2 more sources

