Results 21 to 30 of about 54,764 (254)

Combined multivariate and pathway analyses show that allergen-induced gene expression changes in CD4+ T cells are reversed by glucocorticoids. [PDF]

PLoS ONE, 2012
BACKGROUND: Glucocorticoids (GCs) play a key role in the treatment of allergy. However, the genome-wide effects of GCs on gene expression in allergen-challenged CD4(+) T cells have not been described.
Yelin Zhao, Hui Wang, Mika Gustafsson, Antonella Muraro, Sören Bruhn, Mikael Benson   +5 more
doaj   +1 more source

ROLE OF MOLECULAR INVESTIGATIONS IN DIAGNOSTICS OF PATIENTS WITH POLLEN ALLERGY

Proceedings of the Shevchenko Scientific Society: Medical Sciences, 2018
Introduction. Allergic diseases are one of the frequent disorders of children’s and adults’ health worldwide. Pollen allergy is among the most common allergic diseases.
Svitlana Zubchenko, Valentyna Chopyak
doaj   +1 more source

ALLERGENIC ACTIVITY OF FISH EXTRACT [PDF]

Basrah Journal of Veterinary Research, 2006
A component of Fish extract has been isolated by a combination of 65% ammonium ’ sulphat salt precipitation and gel filtration. The purified allergen appeared as two major peaks. Peak 1 1 exhibited the highest lglj binding inhibition and showed a specific .
R.K, Abdulla, F.A, Bakr, S.S, Mossen
doaj   +1 more source

Components of plant-derived food allergens: Structure, diagnostics, and immunotherapy

Allergology International, 2021
A large number of plant-derived food allergen components have been identified to date. Although these allergens are diverse, they often share common structural features such as numerous disulfide bonds or oligomeric structures.
Nobuyuki Maruyama
doaj   +1 more source

Practical Recommendations for Mixing Allergy Immunotherapy Extracts

Allergy & Rhinology, 2015
Critical aspects of formulating allergy immunotherapy vaccines include the selection, total number, and proportions of each allergen component in therapeutic mixtures.
Barbara J. Daigle M.S.N., F.N.P.-C., Donna J. Rekkerth M.S., F.N.P.   +1 more
doaj   +1 more source

Extended IgE profile based on an allergen macroarray: a novel tool for precision medicine in allergy diagnosis

World Allergy Organization Journal, 2018
Background Precision medicine (PM) is changing the scope of allergy diagnosis and treatment. An in vitro IgE assay, a prototype PM method, was developed in the sixties and has garnered increasing interest because of the introduction of recombinant ...
Enrico Heffler, Francesca Puggioni, Silvia Peveri, Marcello Montagni, Giorgio Walter Canonica, Giovanni Melioli   +5 more
doaj   +1 more source

Multiplex IgE peanut panels: a critical appraisal of assay designs and the good, the bad, and the ugly features of the applied allergen components

Frontiers in Allergy
BackgroundMultiplex allergy assays are currently well-established in allergy diagnostics. However, the different assays in terms of designs and performance are also claimed to be heterogeneous as no agreed standards and requirements are available ...
D. de Boer, C. J. J. Bijnens, M. C. Slot, C. M. G. Nieuwhof, J. A. P. Bons   +4 more
doaj   +1 more source

Recent advances in component resolved diagnosis in food allergy

Allergology International, 2016
Due to the high prevalence of food allergic diseases globally there are increasing demands in clinical practice for managing IgE-mediated conditions. During the last decade, component resolved diagnostics has been introduced into the field of clinical ...
Magnus P. Borres, Nobuyuki Maruyama, Sakura Sato, Motohiro Ebisawa   +3 more
doaj   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source