Results 31 to 40 of about 188,190 (277)

Immunological Outcomes of Allergen-Specific Immunotherapy in Food Allergy

Frontiers in Immunology, 2020
IgE-mediated food allergies are caused by adverse immunologic responses to food proteins. Allergic reactions may present locally in different tissues such as skin, gastrointestinal and respiratory tract and may result is systemic life-threatening ...
Ann-Marie Malby Schoos, Ann-Marie Malby Schoos, Dominique Bullens, Dominique Bullens, Bo Lund Chawes, Joana Costa, Liselot De Vlieger, Audrey DunnGalvin, Audrey DunnGalvin, Michelle M. Epstein, Johan Garssen, Johan Garssen, Christiane Hilger, Karen Knipping, Karen Knipping, Annette Kuehn, Dragan Mijakoski, Dragan Mijakoski, Daniel Munblit, Daniel Munblit, Nikita A. Nekliudov, Cevdet Ozdemir, Cevdet Ozdemir, Karine Patient, Diego Peroni, Sasho Stoleski, Sasho Stoleski, Eva Stylianou, Mirjana Tukalj, Mirjana Tukalj, Mirjana Tukalj, Kitty Verhoeckx, Mihaela Zidarn, Willem van de Veen, Willem van de Veen   +34 more
doaj   +1 more source

Successful Allergen-Specific Immunotherapy: Induction of Unresponsiveness by 'Vaccination'. [PDF]

, 2023
The mechanisms of action of allergen-specific immunotherapy (AIT) are often referred to as the induction of 'tolerance'. However, immunological 'tolerance' is defined as an alteration in the function or composition of immune cells.
Daniel E. Speiser, Vogel, Monique, Bachmann, Martin F, Speiser, Daniel E, Monique Vogel, Martin F. Bachmann   +5 more
core   +2 more sources

Nanoparticle–allergen complexes for allergen immunotherapy

International Journal of Nanomedicine, 2017
Allergen-specific immunotherapy was introduced in clinical settings more than 100 years ago. It remains the only curative approach to treating allergic disorders that ameliorates symptoms, reduces medication costs, and blocks the onset of new sensitizations.
Paolo Colombo, Gabriella Di Felice
openaire   +5 more sources

The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthma. [PDF]

, 2014
Blocking the bioactivity of allergens is conceptually attractive as a small-molecule therapy for allergic diseases but has not been attempted previously.
Newton, GK, Jenkins, K, Robinson, C, Garrod, DR, Richardson, JP, Key, RE, Perrior, TR, Major, MR, Firth-Clark, S, Chen, J, Francis-Newton, NJ, Lloyd, SM, Stewart, MR, Zhang, J, Lai, P   +14 more
core   +1 more source

Untersuchungen zur allergen-spezifischen Immuntherapie beim Kleintier [PDF]

, 2005
Im Rahmen einer retrospektiven klinischen Studie wurde die allergen-spezifische Immuntherapie zur Behandlung der CAD und FAD untersucht. Die Ermittlung der Erfolgsrate der beschriebenen Therapie basiert auf der Behand-lung von 117 Hunden.
Schnabl, Britta Simone
core   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Effects of BCG Vaccination Prior to Specific Immunotherapy on IL-4/IFN-γ Ratio and AR Total Symptom Score in Persistent Allergic Rhinitis (Efek vaksinasi BCG pre imunoterapi spesifik terhadap rasio IL-4/IFN-γ dan skor gejala total rinitis pada rinitis alergi persisten) [PDF]

, 2009
Background: Allergic disease including allergic rhinitis (AR) is dominated by Th2 responses with increased production of IL-4 and inhibition of IFN-ï§ production. BCG vaccination induced IL-12 production which promotes Th0 to Th1 shift and stimulates IFN-
Suprihati , Suprihati
core   +1 more source

Immunology of allergen immunotherapy

Immunotherapy Advances, 2022
SummaryAllergen immunotherapy (AIT) is the only disease-modifying therapy for allergic disease. Through repeated inoculations of low doses of allergen—either as whole proteins or peptides—patients can achieve a homeostatic balance between inflammatory effectors induced and/or associated with allergen contact, and mediators of immunologic non ...
Rifat S Rahman, Duane R Wesemann
openaire   +2 more sources

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

The Role of Artificial Intelligence in Modern Allergology: A Review of Applications in Diagnosis, Prediction, and Management

JEADV Clinical Practice, EarlyView.
ABSTRACT Artificial Intelligence is rapidly transforming allergology by enhancing diagnosis, risk prediction, automation, patient communication, education, and therapy development. Machine learning approaches, including convolutional neural networks, recurrent architectures, and transformer‐based models, enable analysis of complex datasets from ...
Sebastian Seurig, Stephan Traidl, Sonja Mathes   +2 more
wiley   +1 more source