Results 71 to 80 of about 30,567 (270)

Allergen Immunotherapy (AIT): a prototype of Precision Medicine

World Allergy Organization Journal, 2015
Precision medicine is a medical model aiming to deliver customised healthcare - with medical decisions, practices, and/or products tailored to the individual patient informed but not directed by guidelines. Allergen immunotherapy has unique immunological
GW Canonica, C. Bachert, P. Hellings, D. Ryan, E. Valovirta, M. Wickman, O. De Beaumont, J. Bousquet   +7 more
doaj   +1 more source

Positive and negative AIT trials: What makes the difference? [PDF]

, 2018
Background: Allergen immunotherapy has proven to be efficacious in allergic rhinitis and asthma. However, results from randomised clinical trials may vary substantially. Clinical trials may unexpectedly fail.
Gerth van Wijk, R. (Roy)
core   +4 more sources

Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang, Teng‐Fei Li, Tian‐Yu Wang, Huan‐Hai Liu   +3 more
wiley   +1 more source

Sublingual house dust mite immunotherapy has no impact on decrease of circulating erythrocytes upon airway allergen challenge in allergic rhinitis

Scientific Reports, 2017
House dust mite (HDM) allergy is a predominant cause for perennial allergic rhinitis (AR) in Europe. We recently reported that circulating erythrocyte numbers decrease after airway allergen challenge in a murine asthma model and in grass-pollen ...
Galateja Jordakieva, Michael Kundi, Patrick Lemell, René Zieglmayer, Petra Zieglmayer, Jasminka Godnic-Cvar, Erika Jensen-Jarolim   +6 more
doaj   +1 more source

A Systematic Review and Meta-Analysis on the Induction of Confirmed Eosinophilic Esophagitis as a Side Effect of Allergen Immunotherapy: An EAACI Task Force Report. [PDF]

Allergy
ABSTRACT The European Academy of Allergy and Clinical Immunology (EAACI) established a Task Force to assess the existing data on the relationship between eosinophilic esophagitis (EoE) and allergen immunotherapy (AIT). This systematic review and meta‐analysis aimed to study the incidence of confirmed EoE, developing as a side effect of AIT to food or ...
Rossi CM, Terreehorst I, Apostolidou E, Votto M, Bakirtas A, Cianferroni A, Konstantinou GN, Pantavou K, Antolin-Amerigo D, Heffler E, Alvarez-Perea A, Fernandez-Rivas M, Nikolopoulos GK, Pfaar O, Pitsios C.   +14 more
europepmc   +2 more sources

Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang, Man‐Hou Chao, Xin Luo, Feng‐Wen Shan, Zi‐Xuan Hua, Ze‐Zhi Guo, Hua‐Mei Yan, He Zhang, Tong Wu, Min Zhou, Rui Zheng, Shuo Wu, Xue‐Kun Huang, Zhao‐Hui Shi, Ya‐Na Zhang, Ji Yang, Qin‐Tai Yang   +16 more
wiley   +1 more source

Requirements for acquiring a high-quality house dust mite extract for allergen immunotherapy

Drug Design, Development and Therapy, 2012
Franco Frati,1 Cristoforo Incorvaia,2 Marie David,3 Silvia Scurati,3 Simona Seta,4 Guglielmo Padua,4 Eleonora Cattaneo,1 Carlo Cavaliere,5 Alessia Di Rienzo,6 Ilaria Dell'Albani,1 Paola Puccinelli11Medical and Scientific and Regulatory Department,
Frati F, Incorvaia C, David M, Scurati S, Seta S, Padua G, Cattaneo E, Cavaliere C, Di Rienzo A, Dell'Albani I, Puccinelli P   +10 more
doaj  

Long-Term Effect of Allergen Immunotherapy in Responder Local Allergic Rhinitis Patients: Symptom Control, and Prevention of Asthma and Allergic Sensitizations. [PDF]

Allergy
LAR patients who respond to AIT during the first year and are treated for two more years continue improving (less symptoms and medication intake) during the following seven years. AIT prevents the onset of asthma and allergic sensitizations in responder LAR individuals during the seven years following discontinuation.
Testera-Montes A, Zubiaga-Fernandez L, Aranda CJ, Garcia-Esteban I, Gaitan-Nievas TI, Sanchez-Torralvo D, Mayorga C, Torres MJ, Eguiluz-Gracia I, Rondon C.   +9 more
europepmc   +2 more sources

The Development of Hypersensitivity Reactions in the Pediatric Population: A Review [PDF]

, 2019
Over the past several years, pediatric allergies have come to the forefront of many studies. Reports of immune-mediated hypersensitivity in younger patients have grown and led to an interest researching the causes of pediatric hypersensitivities.
Burns, Heather
core   +1 more source

Novel birch pollen specific immunotherapy formulation based on contiguous overlapping peptides. [PDF]

, 2013
BACKGROUND: Synthetic contiguous overlapping peptides (COPs) may represent an alternative to allergen extracts or recombinant allergens for allergen specific immunotherapy.
Audran, R., Barbier, N., Boudousquié, C., Corradin, G., Pellaton, C., Perrin, Y., Reymond, C., Spertini, F., Thierry, A.C., Wassenberg, J.   +9 more
core   +1 more source