Results 71 to 80 of about 211,796 (270)

Requirements for acquiring a high-quality house dust mite extract for allergen immunotherapy

Drug Design, Development and Therapy, 2012
Franco Frati,1 Cristoforo Incorvaia,2 Marie David,3 Silvia Scurati,3 Simona Seta,4 Guglielmo Padua,4 Eleonora Cattaneo,1 Carlo Cavaliere,5 Alessia Di Rienzo,6 Ilaria Dell'Albani,1 Paola Puccinelli11Medical and Scientific and Regulatory Department,
Frati F, Incorvaia C, David M, Scurati S, Seta S, Padua G, Cattaneo E, Cavaliere C, Di Rienzo A, Dell'Albani I, Puccinelli P   +10 more
doaj  

Update on mechanisms of allergen injection immunotherapy

, 2008
The incidence of allergic diseases is increasing at an alarming rate, paricularly in countries with a western lifestyle. Currently in the UK, approximately one quarter of the population suffers from seasonal allergic rhinitis.
Durham, S. R., James, Louisa Katherine
core   +1 more source

Microarrayed Allergen Molecules Distinguish IgE Sensitisation to Blomia tropicalis and Dermatophagoides pteronyssinus

Allergy, EarlyView.
This study established a microarray containing a representative panel of purified Blo t and Der p allergens for the identification of patients sensitised to Blo t and/or Der p. Results indicate that the microarray based on Blo t and Der p allergens is a useful tool for the identification of Blo t‐ and/or Der p‐sensitised patients. The microarray may be
Nishelle Dsouza, Siratcha Phanthong, Huey‐Jy Huang, Milena Weber, Eszter Sarzsinszky, Petra Zieglmayer, Gabrielle Pauli, Margarete Focke‐Tejkl, Mikhail Tulaev, Nikolina Todorovic, Walter Keller, Thomas Schlederer, Luis Caraballo, Anchalee Tungtrongchitr, Rudolf Valenta, Pongsakorn Tantilipikorn, Susanne Vrtala   +16 more
wiley   +1 more source

Mechanisms of allergen-specific immunotherapy [PDF]

, 2012
: Allergen-specific immunotherapy (allergen-SIT) is a potentially curative treatment approach in allergic diseases. It has been used for almost 100 years as a desensitizing therapy.
Akdis, C A, Michael B Soyka, Fujita, H, Cezmi A Akdis, Hiroyuki Fujita, Akdis, M, Soyka, M B, Mübeccel Akdis, Fujita Hiroyuki, Soyka MB, Fujita H, Akdis M, Akdis Mübeccel, Akdis CA, Soyka Michael B, Akdis Cezmi A, Akdis, Mübeccel, Soyka, Michael B, Akdis, Cezmi A, Fujita, Hiroyuki   +19 more
core   +2 more sources

Sublingual house dust mite immunotherapy has no impact on decrease of circulating erythrocytes upon airway allergen challenge in allergic rhinitis

Scientific Reports, 2017
House dust mite (HDM) allergy is a predominant cause for perennial allergic rhinitis (AR) in Europe. We recently reported that circulating erythrocyte numbers decrease after airway allergen challenge in a murine asthma model and in grass-pollen ...
Galateja Jordakieva, Michael Kundi, Patrick Lemell, René Zieglmayer, Petra Zieglmayer, Jasminka Godnic-Cvar, Erika Jensen-Jarolim   +6 more
doaj   +1 more source

Allergen Immunotherapy (AIT): a prototype of Precision Medicine

World Allergy Organization Journal, 2015
Precision medicine is a medical model aiming to deliver customised healthcare - with medical decisions, practices, and/or products tailored to the individual patient informed but not directed by guidelines. Allergen immunotherapy has unique immunological
GW Canonica, C. Bachert, P. Hellings, D. Ryan, E. Valovirta, M. Wickman, O. De Beaumont, J. Bousquet   +7 more
doaj   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Untersuchungen zur allergen-spezifischen Immuntherapie beim Kleintier [PDF]

, 2005
Im Rahmen einer retrospektiven klinischen Studie wurde die allergen-spezifische Immuntherapie zur Behandlung der CAD und FAD untersucht. Die Ermittlung der Erfolgsrate der beschriebenen Therapie basiert auf der Behand-lung von 117 Hunden.
Schnabl, Britta Simone
core   +1 more source

DermAll nanomedicine for allergen-specific immunotherapy [PDF]

, 2013
A novel allergen-specific immunotherapy for IgE-mediated allergies is presented in this paper, using an experimental allergic rhinitis model and a synthetic plasmid pDNA/PEIm nanomedicine expressing ovalbumin as model allergen.
Csiszovszki Zsolt, Tőke Enikő R., Molnár Levente, Lőrincz Orsolya, Kemény Lajos, Francziszti, László, Bitai Tamás, Csörgő Sándorné Bata Zsuzsanna, Lőrincz, Orsolya, Molnár, Levente, Bitai, Tamás, Jánossy Tamás, Lisziewicz Julianna, Csiszovszki, Zsolt, Tőke, Enikő Rita, Garaczi, Edina, Jánossy, Tamás, Bata-Csörgő, Zsuzsanna, Kemény, Lajos, Lisziewicz, Julianna, Szabó, Kornélia, Szabó Kornélia Ágnes, Garaczi Edina, Francziszti László   +23 more
core   +1 more source

Exhaled Volatile Organic Compounds Identify Allergic Patients Among Individuals With Chronic Rhinitis

Allergy, EarlyView.
Exhaled decane and nonadecane discriminate allergic (AR + LAR) from non‐allergic (NAR + HC) subjects among individuals with chronic rhinitis. LAR patients display higher levels of exhaled nonadecane than NAR individuals at baseline. Subjects with FeNO≥ 25 ppb have higher levels of exhaled decane, nonanal, and styrene than individuals with FeNO < 25 ppb
Rosa Alba Sola‐Martinez, Laura Zubiaga‐Fernandez, Marta Figuerola, Anyith Cruz‐Amaya, Carlos J. Aranda, Maria J. Torres, Ibon Eguiluz‐Gracia, Carmen Rondon, Teresa De Diego Puente, Almudena Testera‐Montes   +9 more
wiley   +1 more source