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Allergen databases and allergen semantics

Regulatory Toxicology and Pharmacology, 2009
The efficacy of any specific bioinformatic analysis of the potential allergenicity of new food proteins depends directly on the nature and content of the databases that are used in the analysis. A number of different allergen-related databases have been developed, each designed to meet a different need.
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Mite allergens

Current Allergy and Asthma Reports, 2005
There is an increasing awareness of the health implications of mite sensitivity, as it is closely related to asthma. Mite allergy constitutes a complex worldwide problem, with sanitary and economical implications. Not only are mite species present in house dust, producing potent allergens, but other, less studied species are also responsible for ...
Enrique, Fernández-Caldas   +1 more
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Allergen Avoidance

1998
Allergen exposure is a risk factor for sensitisation, prevalence and severity of allergic disease. Effective allergen avoidance strategies have been devised. The cost-benefit in public health terms should be established by prospective controlled studies that are under way around the world.
Custovic, A, Woodcock, A.
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Rodent allergens

Current Allergy and Asthma Reports, 2002
Rodent allergens play a significant role in the pathogenesis of asthma and allergic rhinitis, and are potent causes of acute and chronic symptoms. This has long been apparent in occupational settings, particularly in the laboratory, but has been most recently studied and found to be important in home environments. These allergens have been suggested as
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Animal allergens

Current Allergy and Asthma Reports, 2005
Animal allergen exposure in early childhood and its relationship to the development of atopic disease is a subject that has been evolving rapidly. Recently, several well-designed studies have helped elucidate previous, often conflicting findings on this topic.
Megan Elizabeth, Partridge, Robert, Wood
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Parasite allergens

Molecular Immunology, 2018
Human IgE against helminths is a normal component of the whole protective response elicitesd during infection, when specific IgE to a great number of antigens is produced; however, few of those IgE binding components are actually allergens. In general, considering the strong Th2/IgE responses during helminth infections is intriguing that they are not ...
Luis, Caraballo, Sandra, Coronado
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Cockroach allergens

Current Allergy and Asthma Reports, 2005
Cockroaches produce several potent allergens associated with sensitization and the development of asthma. Many of these allergens have been cloned and produced as biologically active recombinant proteins. Three-dimensional structure and molecular modeling, in addition to studies on the biological functions of these proteins in the cockroach, have ...
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Allergen mimotopes

Methods, 2004
The causative treatment of type I allergies is a long pursued goal in immunology. To design safe and efficient vaccine preparations, the interaction of the allergen and the symptom-inducing IgE antibodies still needs to be better understood. In this article, we describe the use of the phage display technique in allergy.
Angelika, Riemer   +2 more
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Contact allergens

Ugeskrift for Læger
Approximately 5,200 contact allergens are known. Developing and implementing new chemical substances in the industry and the addition of these substances in various commercial products is a continuous process, and new contact allergens are frequently identified.
Kristian Fredløv, Mose   +13 more
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Allergen Databases

2014
In this chapter, five popular allergen databases have been described: (1) Allergome is based on basic and clinical information on allergens causing an IgE-mediated disease; (2) AllergenOnline allows online search of peer-reviewed allergen list; (3) International Union of Immunological Societies Allergen nomenclature subcommittee database contains ...
Gaurab, Sircar   +3 more
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