Results 61 to 70 of about 92,915 (315)

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Dosing Interval Extension of Dupilumab in CRSwNP: Five‐Year Real World Outcomes

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent, often Type 2‐mediated inflammatory disease that markedly impairs quality of life. While dupilumab provides rapid improvement, there is limited evidence on long‐term outcomes beyond 2 years, and the clinical impact of dosing‐interval extension remains unclear.
Nicholas J. Campion, Dioni‐Pinelopi Petsiou, Florian C. Fally, Karina Berbalk, Noah F. Melamed, Aldine Tu, Christina Morgenstern, Fana Alem Kidane, Mohammed Zghaebi, Linda Liu, Minghao Pan, Tina J. Bartosik, Victoria Stanek, Katarina Gangl, Julia Eckl‐Dorna, Sven Schneider   +15 more
wiley   +1 more source

Expressed sequence tag survey of gene expression in the scab mite Psoroptes ovis--allergens, proteases and free-radical scavengers [PDF]

, 2003
Psoroptes ovis, the causative agent of sheep scab, is an important ectoparasitic mite infecting sheep, goats and cattle. Infection is characterized by an extensive dermatitis, scab formation and intense itching.
Blaxter, M L, Knox, D P, Kenyon, F, Whitton, C, Parkinson, J, Welsh, M   +5 more
core  

Omega-5 and Gamma Gliadin are the Major Allergens in Adult-Onset IgE-Mediated Wheat Allergy: Results from Thai Cohort with Oral Food Challenge

Journal of Asthma and Allergy, 2021
Surapon Piboonpocanun,1 Torpong Thongngarm,2 Chamard Wongsa,2 Punchama Pacharn,3 Onrapak Reamtong,4 Mongkhon Sompornrattanaphan2 1Institute of Molecular Biosciences, Mahidol University, Salaya, Nakhonpathom, Thailand; 2Division of Allergy and Clinical ...
Piboonpocanun S, Thongngarm T, Wongsa C, Pacharn P, Reamtong O, Sompornrattanaphan M   +5 more
doaj  

Mass Spectrometry-Based Identification of Bioactive Bee Pollen Proteins: Evaluation of Allergy Risk after Bee Pollen Supplementation

Molecules, 2022
Bee pollen, because of its high content of nutrients, is a very valuable medicinal and nutritional product. However, since its composition is not completely studied, the consumption of this product may cause adverse effects, including allergic reactions.
Eliza Matuszewska, Szymon Plewa, Dagmara Pietkiewicz, Kacper Kossakowski, Joanna Matysiak, Grzegorz Rosiński, Jan Matysiak   +6 more
doaj   +1 more source

Allergen Immunotherapy [PDF]

Mayo Clinic Proceedings, 2007
Allergen immunotherapy involves exposing a patient to a gradually escalating dose of a specific allergen with the intention of decreasing allergic and inflammatory responses, ultimately leading to a sustained decrease in allergic symptoms. A build-up phase (once weekly injections) is followed by a maintenance phase (once monthly injections) that ...
Matthew A, Rank, James T C, Li
openaire   +2 more sources

Allergic Rhinitis Amplifies Asthma Risk in Patients With Chronic Rhinosinusitis: A Large‐Scale Retrospective Cohort Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) are two highly prevalent airway diseases in the United States. While the coexistence of CRS and asthma is well recognized, less is known about the development of new‐onset asthma in CRS, particularly in the context of comorbid AR. This study assessed the impact of CRS and AR on
Austin J. Lee, Mohamad R. Chaaban
wiley   +1 more source

Effects of enzymolysis on allergenicity and digestibility of food allergens

Food Science of Animal Products
Food allergens are a significant concern for global public health. Enzymolysis, which includes enzymatic hydrolysis and enzymatic cross-linking, is known for its mild conditions, as well as its high efficiency and stability, making it a widely employed ...
Jing Yang, Shuling Zhou, Yan Chen, Jiajia Song, Jiawang Jin, Ruiping Gao   +5 more
doaj   +1 more source

EXAMINATION OF THE MOST COMMON ALLERGENS OF CANINE ATOPIC DERMATITIS - A RETROSPECTIVE STUDY

Archives of Veterinary Medicine, 2015
Canine atopic dermatitis (CAD) is one of the most common skin diseases of dogs. It is estimated that 10-15% of the dogs are showing clinical symptoms of this disease.
Nemanja Šubarević, Oliver Stevanović, Natalija Miličić Matić, Nikola Popović   +3 more
doaj   +1 more source

Airborne Alt a 1 Dynamic and Its Relationship with the Airborne Dynamics of Alternaria Conidia and Pleosporales Spores

Journal of Fungi, 2022
Fungal spores are universal atmospheric components associated to allergic reactions. Alternaria (Ascomycota) is considered the most allergenic spore taxa. Alt a 1 is the major allergen of Alternaria and is present also in other Pleosporales.
Concepción De Linares, David Navarro, Rut Puigdemunt, Jordina Belmonte   +3 more
doaj   +1 more source