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Sulfuretin attenuates allergic airway inflammation in mice
Biochemical and Biophysical Research Communications, 2010Sulfuretin is one of the main flavonoids produced by Rhus verniciflua, which is reported to inhibit the inflammatory response by suppressing the NF-κB pathway. Because NF-κB activation plays a pivotal role in the pathogenesis of allergic airway inflammation, we here examined the effect of sulfuretin on an ovalbumin-induced airway inflammation model in ...
Mi-Young, Song +7 more
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Diversity of protein carbonylation in allergic airway inflammation
Free Radical Research, 2008Oxidative stress is involved in asthma. This study assessed the carbonylation of sputum proteins in 23 uncontrolled adult asthmatic patients and 23 healthy controls. Carbonylated proteins (68 kDa and 53 kDa) were elevated in asthmatics when compared to controls and the 68-kDa carbonylated protein was significantly correlated with sputum eosinophilia ...
Katsura, Nagai +7 more
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Roles of Dectin-1 in Allergic Airway Inflammation
Critical Reviews in Immunology, 2017Asthma is a chronic allergic inflammatory disease of the airways. The symptoms can be controlled by inhaled corticosteroids together with long-acting β2 agonists in the majority of patients; however, in some patients, their symptoms remain uncontrolled even under intensive treatment.
Koichi, Hirose +2 more
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The paradigm of cytokine networks in allergic airway inflammation
Current Opinion in Allergy & Clinical Immunology, 2015Cytokines are immunomodulatory proteins important in cell signaling. Complex interactions of innate and adaptive immune cells, as well as structural cells and their cytokines, play crucial roles in regulating allergic airway inflammation. Here, we summarize current knowledge about the potential roles of known and newly identified helper T cells and ...
Ruby, Pawankar +3 more
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Neurotrophins in Chronic Allergic Airway Inflammation and Remodeling
2012Allergic asthma is a chronic inflammatory disease characterized by the production of allergen-specific IgE antibodies, TH2 inflammation, airway hyperresponsiveness and airway remodeling. Airway remodeling represents the disease-limiting stage during disease progression, and the underlying cellular molecular network resulting in airway remodeling are ...
Harald, Renz, Ayşe, Kiliç
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Eosinophils and basophils in allergic airway inflammation
Journal of Allergy and Clinical Immunology, 1994W W, Busse +3 more
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Nasal and bronchial airway reactivity in allergic and non allergic airway inflammation
2003In allergic or asthmatic airways disease, upper and lower airways show a uniform eosinophilic inflammation of the mucosa, and bronchial hyperreactivity is a common finding. To study the co- variation of mucosal reactivity in upper and lower airways, histamine challenges of both sites were performed in a group of patients with allergic rhinitis during ...
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Let-7 microRNA–mediated regulation of IL-13 and allergic airway inflammation
Journal of Allergy and Clinical Immunology, 2011Ankur Kulshreshtha +2 more
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House Dust Mite Interactions with Airway Epithelium: Role in Allergic Airway Inflammation
Current Allergy and Asthma Reports, 2013Harissios Vliagoftis +1 more
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