Results 161 to 170 of about 221,385 (308)

In Vitro Evaluation of the Inhibitory Effects of Linarin on Histamine‐Induced Expression of Proinflammatory Cytokines, Mucin 5AC, and Aquaporin 5 in Human Nasal and Bronchial Epithelial Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Allergic rhinitis and asthma are two prevalent chronic allergic conditions in children. Linarin, a glycosylated flavonoid derived from various plants, exhibits a wide range of biological activities. This study aimed to investigate the therapeutic potential of linarin against allergic rhinitis and asthma.
Xin‐Jing Mi, Jie Wang, Jian‐Qiang Qi
wiley   +1 more source

Safety and Effectiveness of Allergen Immunotherapy in Patients with Severe Allergic Asthma. [PDF]

J Asthma Allergy
Tabar AI, Delgado-Romero J, González-Mancebo E, Domínguez-Ortega J, Soto-Retes L, Asthma and Immunotherapy Group of the SEAIC.   +5 more
europepmc   +1 more source

Potential Biomarkers for Disease Stratification and Prognosis Prediction in Pediatric Asthma: LCN2, sST2 and FGF21

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang, Hai Wang, Yong‐Zheng Zhang, Yan‐Yan Chen, Xin‐Xin Xing, Yi‐Cheng Ding   +5 more
wiley   +1 more source

Clinical Utility of Central and Peripheral Airway Nitric Oxide in Children with Different Types of Allergic Asthma. [PDF]

J Asthma Allergy
Zhu S, Zhao R, Tang Y, Xie Y, Dong X.
europepmc   +1 more source

PDCD5 Contributes to Airway Epithelial Cell Damage via Mitochondrial Pathway and Participates in COPD Pathogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan, Rui Zhang, Yu‐er Li, Rui Li, Shao‐bo Ge, Jin Liu, Shi‐yuan Yao, Xia Yang, Tao Zhang, Ming Zhang   +9 more
wiley   +1 more source

Analysis of intestinal microorganisms and metabolite in childhood allergic asthma: role in assessing the severity of condition in children. [PDF]

Front Pediatr
Xu Z, Ma H, Liu Y, Liang S, Liao Z.
europepmc   +1 more source

Adenotonsillar Microbiome Shifts in Children With Obstructive Sleep Apnea Syndrome

The Laryngoscope, EarlyView.
This study compares the microbiomes of adenoids and tonsils in pediatric OSAS patients and healthy controls using 16S rRNA sequencing. Significant differences were found in the tonsillar microbiome of OSAS patients, with lower alpha diversity and an overrepresentation of pathogenic genera like Haemophilus and Neisseria, while adenoid microbiomes showed
Oded Kraus, Yehuda Schwarz, Yair Motro, Tal Marom, Ron Lamdan, Vadim Kapuller, Sharon Tamir Ovnat, Jacob Moran‐Gilad   +7 more
wiley   +1 more source

Identification of diagnostic genes and drug prediction of allergic asthma by integrated bioinformatics analysis, machine learning, and molecular docking. [PDF]

World Allergy Organ J
Wang H, Wang R, Lan J, Zhang W, Li G, Nie H, Ran L.   +6 more
europepmc   +1 more source

Long‐Term Cost Utility Analysis of Endoscopic Sinus Surgery: Analysis of 5‐Year Outcomes

The Laryngoscope, EarlyView.
This study utilizes a cohort‐style Markov decision tree economic model to evaluate the long‐term (5‐year) cost‐effectiveness of endoscopic sinus surgery versus medical management for patients with chronic rhinosinusitis. The results show that the endoscopic sinus surgery strategy cost more ($63,296.27) but yielded increased quality‐adjusted life years (
Dara R. Adams, Katherine Tashman, Eric H. Holbrook, Stacey T. Gray, Ralph Metson, George Scangas   +5 more
wiley   +1 more source

Evidence of Eczematous Skin Characteristics in Mild Allergic Asthma. [PDF]

Clin Transl Allergy
Senavonge A, Cusack RP, Whetstone CE, Alsaji N, Howie KJ, Stevens C, Wattie J, Wiltshire L, Sehmi R, O'Byrne PM, Lima H, Gauvreau GM.   +11 more
europepmc   +1 more source