Results 171 to 180 of about 221,385 (308)

Impact of Obesity on the Structured Histopathology of Chronic Rhinosinusitis Patients

The Laryngoscope, EarlyView.
ABSTRACT Objectives Obesity is an established risk factor for asthma, which shares common inflammatory pathways with chronic rhinosinusitis (CRS). However, the link between obesity and CRS remains poorly understood. By identifying trends in the structured histopathology (SHP) of obese patients with CRS, we aim to better understand how changes in the ...
Daniel X. Ma, Sushanth Neerumalla, Ali Baird, Russell A. Whitehead, Peter Filip, Bobby A. Tajudeen, Pete S. Batra, Peter Papagiannopoulos   +7 more
wiley   +1 more source

Metabolomics reveals pro-inflammatory effects of 12R-HETE and ALOX12B in maternal allergic asthma. [PDF]

Commun Biol
Wang L, Wang X, Wang W, Sun Z, Fang H, Qi C, Lin W, Lin L, Xie T, Shen C, Shi C, Xu J, Ge F, Shan J.   +13 more
europepmc   +1 more source

Polyphenolic Activation of Basophils Explains Alcohol Hypersensitivity in AERD

The Laryngoscope, EarlyView.
The mechanism behind alcohol sensitivity in AERD has not been previously characterized. This study demonstrates the activation of basophils in patients with CRSwNP and AERD by polyphenolic compounds, but not ethanol. Since these compounds can be found in alcoholic beverages in similar frequencies by which they trigger symptoms, this research provides a
Spencer C. Payne, William Eschenbacher, Ryan Stepp, Larry Borish   +3 more
wiley   +1 more source

Correction: Effect of PM_2.5 exposure on susceptibility to allergic asthma in elderly rats treated with allergens. [PDF]

Sci Rep
Zhao L, Ding X, Zhou L, Song C, Kang T, Xu Y, Liu Y, Han Y, Zhao W, Zhang B, Xu D, Guo J.   +11 more
europepmc   +1 more source

Early Surgery Reduces Psychiatric and Learning Disorder Risk in Pediatric Sleep‐Disordered Breathing

The Laryngoscope, EarlyView.
ABSTRACT Objective To determine whether the type and timing of intervention for pediatric sleep‐disordered breathing (SDB) affect the risk of developing neuropsychiatric and learning disorders. Methods A retrospective cohort study using TriNetX, from January 2016 to March 2025, was conducted.
Daniel J. Campbell, W. Jack Palmer, Leonard E. Estephan, Hani Samarah, Elliott Sina, Nicole Aaronson, William Parkes   +6 more
wiley   +1 more source

Allergic Asthma in Children: The Hidden Role of Cockroaches. [PDF]

Pediatr Pulmonol
Indolfi C, Klain A, Grella C, Capuano MC, Perrotta A, Dinardo G, Miraglia Del Giudice M.   +6 more
europepmc   +1 more source

The Impact of Estrogen on Stromal Elements in the Proximal Airway in Idiopathic Subglottic Stenosis

The Laryngoscope, EarlyView.
ABSTRACT Objectives Idiopathic subglottic stenosis (iSGS) is an unexplained fibrosis of the proximal airway that predominantly impacts Caucasian women. Clinically, premenopausal patients suffer from higher recurrence rates, potentially implicating ovarian hormone 17B‐estradiol (E2) in disease pathogenesis.
Emily L. Mace, Evan Clark, Edward Talatala, Maxim Litvak, Matthew A. Buendia, Yash A. Choksi, Hongmei Wu, Yueli Zhang, Alexander Hillel, Sam Collins, Quanhu Sheng, Jing Yang, Jason Park, Alexander Gelbard   +13 more
wiley   +1 more source

NLRP3 regulates epithelial barrier integrity and protects from airway hyperresponsiveness in experimental allergic asthma. [PDF]

Front Immunol
DeStefano S, Grychtol R, Funken D, Habener A, Tamm S, Stanke F, Greiner W, Beyer K, Hamelmann E, Kabesch M, von Mutius E, Schaub B, Jirmo AC, Hansen G, CHAMP study group.   +14 more
europepmc   +1 more source

Inflammatory Markers Stratify Surgical Outcomes in Pediatric Airway Reconstruction

The Laryngoscope, EarlyView.
ABSTRACT Objectives Red blood cell distribution width (RDW) predicts surgical success in adult patients undergoing open airway reconstruction for laryngotracheal stenosis, but similar biomarkers in pediatrics remain unidentified. This study identifies predictors of outcomes in pediatric patients undergoing triple endoscopy or surgical airway ...
Nomongo Dorjsuren, Hrithik Praveen, Kalpnaben Patel, Shilin Zhao, Alexander Gelbard, Christopher Wootten   +5 more
wiley   +1 more source

Identifying therapeutic targets for allergic asthma through atopic dermatitis-associated genetic mechanisms. [PDF]

J Allergy Clin Immunol Glob
Pu Y, Liu J, Bennett AN, Chan KHK.
europepmc   +1 more source