Results 201 to 210 of about 221,385 (308)

Recent Progress in Treating Airway Mucus Hypersecretion by Targeting the Epidermal Growth Factor Receptor Signaling Pathway

Pediatric Discovery, EarlyView.
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang, Fuping Yang, Chunyu Yan, Yu Deng, Enmei Liu   +4 more
wiley   +1 more source

Tartrate-Resistant Acid Phosphatase 5 (TRAP5) Promotes Eosinophil Migration During Allergic Asthma. [PDF]

Am J Respir Cell Mol Biol
Padra M, Bergwik J, Adler A, Marcoux G, Bhongir RKV, Papareddy P, Egesten A.   +6 more
europepmc   +1 more source

Glucocorticoid‐Induced TNFR‐Related Ligand as a Biomarker for Diagnosis and Severity of Asthma in Children

Pediatric Discovery, EarlyView.
Our study demonstrates elevated GITRL expression in HDM‐exposed dendritic cells (in vitro), murine asthma models, and pediatric asthma patients, and reveals a direct association between GITRL levels and disease severity in children. ABSTRACT Currently, there are no reliable pediatric biomarkers for assessing the severity of asthma. Therefore, the study
Yuehan Li, Yan Li, Jinying Xiang, Yinying Ren, Mi Zhou, Fang Deng, Zhou Fu, Fengxia Ding   +7 more
wiley   +1 more source

ST2⁺ Erythroid Progenitors Suppress Allergic Asthma by Scavenging IL-33 in Young Mice. [PDF]

Clin Transl Allergy
Li C, Liu J, Li X, Chen W, Zhang Y, Sun H, Zheng C, Liu Q.   +7 more
europepmc   +1 more source

Proteomic and Lipidomic Profiling of Immune Cell‐Derived Subpopulations of Extracellular Vesicles

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are heterogeneous and play important roles in intercellular communication, contributing to physiological and pathological processes. Since few markers currently exist to differentiate subtypes of EVs, this study aimed to determine proteomic and lipidomic differences among four EV subpopulations. Large and small EVs
Anna Lischnig, Nasibeh Karimi, Per Larsson, Karin Ekström, Rossella Crescitelli, Anna‐Carin Olin, Cecilia Lässer   +6 more
wiley   +1 more source

Paediatric Allergic Asthma: Risk Factors, Diagnosis, Control, and Treatment. [PDF]

Children (Basel)
Indolfi C, Klain A, Giudice MMD, Tosca MA.   +3 more
europepmc   +1 more source

Weathering the storms of climate change: Preparing persons with disabilities and the physiatrists who provide their care for extreme hurricanes

PM&R, EarlyView.
Abstract Climate‐driven disasters have disproportionate and often devastating consequences on individuals with disabilities. Warming ocean and air temperatures are fueling more extreme tropical cyclones, further endangering those living in at‐risk regions.
Mollie Andreae, James M. Shultz, J. Marshall Shepherd, Zelde Espinel, Lauren T. Shapiro   +4 more
wiley   +1 more source

Preparation of ESAT6-Fc Fusion Protein and Its Therapeutic Efficacy and Immune Mechanisms in Allergic Asthma Mice via Intranasal Immunization. [PDF]

Molecules
Wang J, Hai M, Yang Y, Wang T, Zhang W, Ma R, Sun M, Qin Y, Yang Y, Dong Z, Yang M, Wan Q.   +11 more
europepmc   +1 more source

Allergic asthma.

Minnesota medicine, 2004
openaire   +1 more source

Association of autoimmune diseases with biologic agents targeting type 2 immunity: An observational study using a claims database

Rheumatology &Autoimmunity, EarlyView.
This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley   +1 more source