Epigenomics and allergic disease [PDF]
Allergic disease development is affected by both genes and the environment, and epigenetic mechanisms are hypothesized to mediate these environmental effects.
Ziyab, Ali H. +5 more
core +4 more sources
Kawasaki Disease and Allergic Diseases [PDF]
Background: Kawasaki disease (KD) is an inflammatory disorder with an unknown etiology. It is the leading cause of acquired heart disease, which leads to coronary vasculitis among children. Studies of frequent manifestation of allergic diseases in children with KD have been the subject of mounting clinical interest.
Po-Yu Huang +6 more
openaire +3 more sources
Nutrition and Allergic Diseases [PDF]
The development of IgE-mediated allergic diseases is influenced by many factors, including genetic and environmental factors such as pollution and farming, but also by nutrition. In the last decade, substantial progress has been made in our understanding of the impact that nutrition can have on allergic diseases. Many studies have addressed the effect
van Neerven, R.J.J., Savelkoul, Huub
openaire +5 more sources
The effect of macrolides on allergic rhinitis versus chronic rhinosinusitis- an in-vitro study [PDF]
PhDBackground The mechanisms of the rhinitic process are complex. Previous studies upon nasal epithelial cells have begun to investigate rhinitis.
Kuchai, Romana
core +4 more sources
Environmental degradation and the increasing burden of allergic disease: The need to determine the impact of nitrogen pollution [PDF]
Allergic diseases are a major public health problem and their burden is expected to keep increasing as a result of various interactions between changes in the environment and lifestyle.
Aerts, Raf +24 more
core +1 more source
Genetics of allergic disease [PDF]
Atopy can express itself as asthma, rhinitis and eczema. The presence of atopy can be assessed by increased levels of total serum IgE and specific IgE to common allergens, skin test positivity and increased numbers of peripheral blood eosinophils. Genetic studies indicate that multiple genes are involved in the pathogenesis of atopy and that different ...
Feijen, M, Gerritsen, J, Postma, DS
openaire +3 more sources
The therapeutic potential of the filarial nematode-derived immunodulator, ES-62 in inflammatory disease [PDF]
The dramatic recent rise in the incidence of allergic or autoimmune inflammatory diseases in the West has been proposed to reflect the lack of appropriate priming of the immune response by infectious agents such as parasitic worms during childhood ...
Harnett, M.M. +2 more
core +4 more sources
Human Schistosome Infection and Allergic Sensitisation [PDF]
Several field studies have reported an inverse relationship between the prevalence of helminth infections and that of allergic sensitisation/atopy. Recent studies show that immune responses induced by helminth parasites are, to an extent, comparable to ...
Francisca Mutapi +5 more
core +1 more source
Overweight/obesity and respiratory and allergic disease in children: international study of asthma and allergies in childhood (ISAAC) phase two. [PDF]
BACKGROUND: Childhood obesity and asthma are increasing worldwide. A possible link between the two conditions has been postulated. METHODS: Cross-sectional studies of stratified random samples of 8-12-year-old children (n = 10 652) (16 centres in ...
Forastiere, Francesco +39 more
core +3 more sources
Effects of early life paracetamol use on the incidence of allergic disease and sensitization: 5 year follow-up of an Ethiopian birth cohort. [PDF]
INTRODUCTION: The hypothesis that paracetamol, one of the most widely used medicines, may increase the risk of asthma and allergic disease is of obvious importance but prospective cohort data looking at dose and timing of exposure are lacking. OBJECTIVE:
Amberbir, Alemayehu +18 more
core +1 more source

