Protective and risk factors for childhood asthma in observational birth cohorts : the role of vitamin D and allergic rhinitis [PDF]
, 2015 Summary Background: Asthma is an inflammatory disease of the airways of the lung. There has been an increase in the prevalence of asthma and other allergic diseases over the past decades and, due to its high prevalence, it is of major public health ...
Rochat, Mascha K.
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The Endogenous Th17 Response in NO
, 2013 Severe, glucocorticoid-resistant asthma comprises 5-7% of patients with asthma. IL-17 is a biomarker of severe asthma, and the adoptive transfer of Th17 cells in mice is sufficient to induce glucocorticoid-resistant allergic airway disease.
Suratt, Benjamin T. +45 more
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Suppression of allergic airway inflammation by helminth-induced regulatory T cells [PDF]
, 2005 Allergic diseases mediated by T helper type (Th) 2 cell immune responses are rising dramatically in most developed countries. Exaggerated Th2 cell reactivity could result, for example, from diminished exposure to Th1 cell–inducing microbial infections ...
Lamb, Jonathan +11 more
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Immunomodulation of Allergic Disease [PDF]
Annual Review of Medicine, 2009 This review focuses on sublingual immunotherapy (SLIT), toll-like receptor-9 (TLR-9) vaccines using cytosine phosphorothioate guanosine (CpG)–allergen conjugates, and anti-IL-5 as novel immunomodulating therapies in allergy. At present, all three approaches are investigational in the United States and require further study to determine their safety and
openaire +2 more sources
Genetics of Allergic Diseases [PDF]
Immunology and Allergy Clinics of North America, 2015 Genome-wide association studies (GWAS) have been employed in the field of allergic disease, and significant associations have been published for nearly 100 asthma genes/loci. An outcome of GWAS in allergic disease has been the formation of national and international collaborations leading to consortia meta-analyses, and an appreciation for the ...
Romina A, Ortiz, Kathleen C, Barnes
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Allergic Disorders in Africa and Africans: Is it Primarily a Priority? [PDF]
, 2010 In Africa, the burden of some diseases has been a problem for centuries. The spectrum of African diseases includes allergies, infections, nutritional deficiencies, and natural disasters.
Chilongola, Jaffu Othniel +7 more
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Pediatric Selective IgM Immunodeficiency
Clinical and Developmental Immunology, 2008 Objective. Limited information exists on features of pediatric Selective IgM immunodeficiency (SIgMID). Previously published pediatric cases and 2 new cases are reviewed. Methods.
Marc F. Goldstein +5 more
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Mediators and Cytokines in Persistent Allergic Rhinitis and Nonallergic Rhinitis with Eosinophilia Syndrome [PDF]
, 2012 Background: Patients with nonallergic rhinitis with eosinophilia syndrome (NARES) show typical symptoms of persistent allergic rhinitis (PAR). The aim of the present study was to compare nasal cytokine patterns between NARES and PAR.
Canis, Martin +9 more
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Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY. [PDF]
, 2010 The unparalleled collection of clinical data and biomaterials within the EHDN's REGISTRY can expedite the search for disease modifiers (genetic and environmental) of age at onset and disease progression that could be harnessed for the development of ...
Handley, Olivia J +59 more
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Breast Cancer Survivorship, Quality of Life, and Late Toxicities
Frontiers in Oncology, 2020 Breast cancer is the most frequent cancer in women: in 2018, almost two million cases have been diagnosed all over the world and it represents the principal cause of death from a neoplastic disease in women. In the past years, breast cancer prognosis has
Simone Nardin +14 more
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