Results 1 to 10 of about 384,216 (360)

Immunophenotypes of anti-SARS-CoV-2 responses associated with fatal COVID-19

open access: yesERJ Open Research, 2022
Background The relationship between anti-SARS-CoV-2 humoral immune response, pathogenic inflammation, lymphocytes and fatal COVID-19 is poorly understood.
Julij Šelb   +30 more
doaj   +1 more source

Kawasaki Disease and Allergic Diseases [PDF]

open access: yesFrontiers in Pediatrics, 2021
Background: Kawasaki disease (KD) is an inflammatory disorder with an unknown etiology. It is the leading cause of acquired heart disease, which leads to coronary vasculitis among children. Studies of frequent manifestation of allergic diseases in children with KD have been the subject of mounting clinical interest.
Po-Yu Huang   +6 more
openaire   +3 more sources

T2-high Asthma, Classified by Sputum mRNA Expression of IL4, IL5, and IL13, is Characterized by Eosinophilia and Severe Phenotype

open access: yesLife, 2021
Asthma is a common chronic disease, with different underlying inflammatory mechanisms. Identification of asthma endotypes, which reflect a variable response to different treatments, is important for more precise asthma management.
Matija Rijavec   +4 more
doaj   +1 more source

Hymenoptera Venom Immunotherapy: Immune Mechanisms of Induced Protection and Tolerance

open access: yesCells, 2021
Hymenoptera venom allergy is one of the most severe allergic diseases, with a considerable prevalence of anaphylactic reaction, making it potentially lethal.
Ajda Demšar Luzar   +4 more
doaj   +1 more source

The effect of residential urban greenness on allergic respiratory diseases in youth: A narrative review [PDF]

open access: yes, 2020
Background: Environmental exposures across the life course may be a contributor to the increased worldwide prevalence of respiratory and allergic diseases occurring in the last decades.
Asta F   +5 more
core   +1 more source

Ribosomal Dysfunction Is a Common Pathomechanism in Different Forms of Trichothiodystrophy

open access: yesCells, 2023
Mutations in a broad variety of genes can provoke the severe childhood disorder trichothiodystrophy (TTD) that is classified as a DNA repair disease or a transcription syndrome of RNA polymerase II.
Gaojie Zhu   +8 more
doaj   +1 more source

Current and emerging biologic therapies targeting eosinophilic disorders

open access: yesWorld Allergy Organization Journal, 2022
Eosinophilic disorders include a wide array of conditions in which eosinophils play a primary pathophysiologic role. While historically treated with corticosteroids and immunosuppressants, knowledge of eosinophil biology has led to the development of ...
Mitchell M. Pitlick, MD   +2 more
doaj   +1 more source

Risks and safety of biologics: A practical guide for allergists

open access: yesWorld Allergy Organization Journal, 2023
Biologic agents are a rapidly expanding class of medications, and several options are now available for the management of allergic and immunologic disorders.
Andrea N. Sitek, MD   +2 more
doaj   +1 more source

RUNX3 mediates keloid fibroblast proliferation through deacetylation of EZH2 by SIRT1

open access: yesBMC Molecular and Cell Biology, 2022
Background Keloid is a benign proliferative fibrous disease featured by excessive fibroblast proliferation after skin injury. However, the mechanism of abnormal cell proliferation is still unclear.
Hanye Liu   +8 more
doaj   +1 more source

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