Results 221 to 230 of about 163,346 (259)
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Pathophysiology of allergic inflammation
Immunological Reviews, 2009Summary: Allergic inflammation is due to a complex interplay between several inflammatory cells, including mast cells, basophils, lymphocytes, dendritic cells, eosinophils, and sometimes neutrophils. These cells produce multiple inflammatory mediators, including lipids, purines, cytokines, chemokines, and reactive oxygen species.
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Thioredoxin in Allergic Inflammation
International Archives of Allergy and Immunology, 2011Thioredoxin (TRX) is a redox-active protein that regulates reactive oxidative metabolism and plays a crucial role in the antioxidant system in regulating the reduction/oxidation balance by scavenging reactive oxygen species, which is implicated in the mechanism of asthma.
Wataru, Ito +7 more
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Platelets and allergic inflammation
Clinical & Experimental Allergy, 2014SummaryIrrefutable clinical evidence demonstrates the activation of platelets in allergic diseases, including asthma, allergic rhinitis, and eczema. Indeed, experimental models of allergic disease have now shown that platelets play a fundamental role in the tissue recruitment of leucocytes following exposure to allergens. Furthermore, the extravascular
Page, Clive, Pitchford, Simon
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Current Allergy and Asthma Reports, 2005
Several genes, including ADAM33, DPP10, PHF11, GPRA, and TIM-1, have been implicated in the pathogenesis and susceptibility to atopy and asthma. Advances have been made in defining the mechanism for the control of allergic airway inflammation in response to inhaled antigens.
Devendra K, Agrawal, Arpita, Bharadwaj
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Several genes, including ADAM33, DPP10, PHF11, GPRA, and TIM-1, have been implicated in the pathogenesis and susceptibility to atopy and asthma. Advances have been made in defining the mechanism for the control of allergic airway inflammation in response to inhaled antigens.
Devendra K, Agrawal, Arpita, Bharadwaj
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Immunotherapy and allergic inflammation
Clinical & Experimental Allergy, 1991A double-blind placebo-controlled trial of allergen injection immunotherapy in adult patients with severe summer hayfever. We used a partially purified biologically standardised grass pollen depot preparation (Alutard SQ, ALK Denmark Ltd.). Immunotherapy was extremely effective in reducing symptoms and medication requirements.
S R, Durham +5 more
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Non-allergic Eosinophilic Inflammation
Immunological Investigations, 2006Much is known about the eosinophilic processes associated with antigens, tumors, and infection, yet data on other causes of eosinophilic inflammation are scarce. This paper investigates the locations and causes of other nonrespiratory eosinophilic inflammation.
Gönlügür, Tanseli, Gönlügür, Uğur
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Allergic and Anaphylactoid Inflammation
JAMA: The Journal of the American Medical Association, 1967To the Editor:— The first reports on allergic phenomena uniformly stressed that sensitization produces a state without protection (anaphylaxis) against minimal amounts of the antigen. Testing procedures for the detection of allergies are only reliable when carried out with minimal amounts of the allergen.
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Eosinophil adhesion in allergic inflammation
Journal of Allergy and Clinical Immunology, 1994Eosinophil adhesion has been studied in some detail in recent years, and a number of interesting observations have emerged. As with other aspects of eosinophil biology, there appears to be a greater similarity with basophils than with neutrophils in their pattern of adhesion interactions.
Wardlaw, AJ, Symon, FS, Walsh, GM
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Glycosaminoglycans and the Regulation of Allergic Inflammation
Current Drug Target -Inflammation & Allergy, 2004Glycosaminoglycans (GAGs) are large, polyanionic molecules expressed throughout the body. The GAG heparin, co-released with histamine, is synthesised by and stored exclusively in mast cells, whereas the closely related molecule heparan sulphate is expressed, as part of a proteoglycan, on cell surfaces and throughout tissue matrices. These molecules are
Rose, M J, Page, C
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CC chemokines in allergic inflammation
Immunology Today, 1994CC chemokines are small inducible proteins that are related to interleukin 8. Recent studies have shown that several CC chemokines, MCP-1, MCP-3, RANTES and MIP-1 alpha, act on basophils and/or eosinophils via GTP-binding protein-coupled receptors. Marco Baggiolini and Clemens Dahinden discuss the involvement of CC chemokines in the recruitment and ...
Baggiolini M, Dahinden CA
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