Applying the adverse outcome pathway (AOP) for food sensitization to support in vitro testing strategies [PDF]
Background Before introducing proteins from new or alternative dietary sources into the market, a compressive risk assessment including food allergic sensitization should be carried out in order to ensure their safety.
Benedé, Sara+14 more
core +1 more source
C1 inhibitor deficiency: 2014 United Kingdom consensus document [PDF]
C1 inhibitor deficiency is a rare disorder manifesting with recurrent attacks of disabling and potentially life-threatening angioedema. Here we present an updated 2014 United Kingdom consensus document for the management of C1 inhibitor-deficient ...
Ashworth, F+11 more
core +3 more sources
Immunology of metal allergies [PDF]
SummaryAllergic contact hypersensitivity to metal allergens is a common health concern worldwide, greatly impacting affected individuals with regard to both quality of life and their ability to work. With an estimated 15–20 % of the Western population hypersensitive to at least one metal allergen, sensitization rates for metallic haptens by far ...
Matthias Goebeler, Marc Schmidt
openaire +3 more sources
Implementation of anaphylaxis management guidelines [PDF]
Anaphylaxis management guidelines recommend the use of intramuscular adrenaline in severe reactions, complemented by antihistamines and corticoids; secondary prevention includes allergen avoidance and provision of self-applicable first aid drugs.
Gough, Hannah+12 more
core +1 more source
WAO guideline for the management of hereditary angioedema [PDF]
Hereditary Angioedema (HAE) is a rare disease and for this reason proper diagnosis and appropriate therapy are often unknown or not available for physicians and other health care providers.
Aygören-Pürsün, Emel+17 more
core +1 more source
ARIA 2016 : Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle [PDF]
European Innovation Partnership on Active and Healthy Ageing Reference Site MACVIA-France, EU Structural and Development Fund Languedoc-Roussillon, ARIA.Peer reviewedPublisher ...
Agache, I+6 more
core +1 more source
Challenges in interpreting allergen microarrays in relation to clinical symptoms: a machine learning approach. [PDF]
Identifying different patterns of allergens and understanding their predictive ability in relation to asthma and other allergic diseases is crucial for the design of personalized diagnostic tools.Allergen-IgE screening using ImmunoCAP ISAC(®) assay was ...
Altmann+22 more
core +1 more source
What's new in the diagnosis and management of food allergy in children? [PDF]
This article reviews the recent advances in the diagnosis and management of IgE mediated food allergy in children. It will encompass the emerging technology of component testing; moves to standardization of the allergy food challenge; permissive diets ...
Campbell, DE, Turner, PJ
core +1 more source
Sublingual allergen immunotherapy with a liquid birch pollen product in patients with seasonal allergic rhinoconjunctivitis with or without asthma [PDF]
Background: Sublingual allergen immunotherapy (SLIT) has been demonstrated to be both clinically efficacious and safe. However, in line with the current regulatory guidance from the European Medicines Agency, allergen immunotherapy (AIT) products must ...
Bachert, Claus+10 more
core +2 more sources
Concentrations of Cysteinyl Leukotrienes in Various Biological Fluids of Children with Bronchial Asthma, Atopic Dermatitis and Food Protein Induced Enterocolitis [PDF]
Clinical manifestation of food allergy is characterized by polymorphic cutaneous, respiratory and gastrointestinal syndromes. Leukotrienes occupy a key place in the pathogenesis of a wide range of inflammatory diseases, including bronchial asthma ...
Haiduchyk, H. (Halyna)+1 more
core +3 more sources