Results 61 to 70 of about 16,423 (253)

Pro‐ATO/Allicin Liposomes for Dual‐Pathway Targeting of p53‐Mutant Tumors

Advanced Science, EarlyView.
Schematic illustration of the “pro‐ATO”/allicin liposomal strategy. Liposomal encapsulation improves the stability and bioavailability of both agents while masking allicin's odor. Upon release in the tumor microenvironment, ATO reactivates structural p53 mutants, and allicin inhibits ATR signaling while releasing H2S, collectively inducing synthetic ...
Xiaoling Xu, WeiYi Cheng, Menghang Yang, Li He, WeiYe Ren, JingQuan Chen, LiTing He, Dandan Bao, Zhihong Zhu, Lixin Wang, Qinghua Yao, Ji‐Gang Piao   +11 more
wiley   +1 more source

Effect of artemisinin combined with allicin on improving cardiac function, fibrosis and NF-κB signaling pathway in rats with diabetic cardiomyopathy.

Acta Biochimica Polonica, 2023
Myocardial fibrosis and inflammation cause cardiac hypertrophy, arrhythmias, and heart failure in diabetics, a leading cause of mortality. Since it's complicated, no drug treats diabetic cardiomyopathy.
Lingjuan Kong, Xiaoqing Ji, Yan Liu, YingJie Du   +3 more
semanticscholar   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

In Silico Screening of Potential Allicin Compound From Allium Sativum as Antiplasmodium [PDF]

, 2015
Allicin compound (2-propene-1- sulphinothioat acid S-2-propenyl ester) is known to have potential as antiplasmodium in vitro. However, the inhibitory activity mechanism of Allicin to plasmodium is still unknown.
Fatmawaty, F. (Fatmawaty), Hanafi, M. (Muhammad), Prasasty, V. D. (Vivitri), Rosmalena, R. (Rosmalena)   +3 more
core  

Redox Modulation at Work: Natural Phytoprotective Polysulfanes From Alliums Based on Redox-Active Sulfur [PDF]

, 2018
Purpose of review: This article provides a brief overview of natural phytoprotective products of allium with a special focus on the therapeutic potential of diallyl polysulfanes from garlic, their molecular targets and their fate in the living organisms.
A Anwar, A Anwar, A Anwar, A Arunkumar, A Das, A Muller, AA Powolny, BA Iwalokun, BC Lee, C Chen, C Jacob, C Oosthuizen, CD Fisher, CJ Cavallito, CS Yang, D Liang, D Wallock-Richards, D Xiao, DM Davenport, DR Allah, E Germain, EA O'Gara, EA O'Gara, F Aala, F Zhang, G Ferrer-Sueta, G Filomeni, G Li, G Li, GA Benavides, GC Wallace, H Fujisawa, H Jurkowska, H Nakagawa, H Nian, H Tsuchiya, HC Wang, HT Hassan, I Gull, I Gull, J Antosiewicz, J Taucher, Jana Reiter, JM Bradley, K Chandra-Kuntal, KC Lai, KL Liu, L Cellini, L Masip, L Yi, LD Lawson, M Abouelfetouh, M Iciek, M Zardast, Małgorzata Iciek, MB Iciek, MC Gruhlke, Michael Puccinelli, MM Fani, MW Ha, N Druesne, NEB Saidu, NEB Saidu, P Gong, P Mikaili, P Rattanachaikunsopon, Qing Liu, RR Cutler, S Ankri, S Kim, S Shetty, SD Stan, SK Saha, T Hosono, T Schneider, T Seki, Toyohiko Ariga, U Münchberg, VA Kiesel, WR Li, X-y Lei, XY Jiang, Y Liu, Y Shadkchan, YA Kim, YR Cai, Z Shigemi, Z Wang, ZM Ross   +88 more
core   +1 more source

REACTION OF ALLICIN-RELATED COMPOUNDS WITH PROTEIN

THE JOURNAL OF VITAMINOLOGY, 1964
Native or urea-denatured egg albumin was allowed to react with C3H7SSC3H7 (I) or C3H7SSOC3H7 (II) under a certain condition. The protein was precipitated by ethanol treatment and the unreacted I or II was completely removed by extracting the precipitate several times with hot ethanol.
I, UTSUMI, K, HARADA, K, KOHNO
openaire   +3 more sources

Looking for Greener Pastures: In Vitro Screening of Phytogenics for the Control of Sparicotyle chrysophrii in Gilthead Sea Bream

Journal of Fish Diseases, EarlyView.
ABSTRACT The gill parasite Sparicotyle chrysophrii poses a significant threat to gilthead sea bream (Sparus aurata) aquaculture in the Mediterranean, causing considerable mortality and economic losses. As traditional chemotherapeutic treatments, like formalin, face growing regulatory restrictions, there is an urgent need for alternative control ...
Teresa Pirollo, Ana León, Monica Caffara, Alice Caneschi, Itziar Estensoro, Jinni Gu, Maurizio Scozzoli, Ariadna Sitjà‐Bobadilla, Oswaldo Palenzuela   +8 more
wiley   +1 more source

Therapeutic potentials of allicin in cardiovascular disease: advances and future directions

Chinese Medicine
Cardiovascular disease (CVD) remains the predominant cause of mortality and disability worldwide. Against this backdrop, finding effective drugs for the pharmacological treatment of CVD has become one of the most urgent and challenging issues in medical ...
Yijie Gao, Baofu Wang, Gaofeng Qin, Shichao Liang, Jiajie Yin, Hong Jiang, Mengru Liu, Xianlun Li   +7 more
semanticscholar   +1 more source

Allicin in Digestive System Cancer: From Biological Effects to Clinical Treatment

Frontiers in Pharmacology, 2022
Allicin is the main active ingredient in freshly-crushed garlic and some other allium plants, and its anticancer effect on cancers of digestive system has been confirmed in many studies.
Yang-yang Zhou, Xingxu Li, Wenyu Luo, Junfeng Zhu, Jingwen Zhao, Mengyao Wang, L. Sang, B. Chang, Bing-yuan Wang   +8 more
semanticscholar   +1 more source

Cellulose‐Based Nanocomposites in Drug Delivery and Antimicrobial Therapies: Emerging Innovations and Translational Outlook

MedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
Applications of cellulose‐based nanocomposites in antimicrobial drug delivery. ABSTRACT Cellulose‐based nanocomposites have emerged as sustainable and versatile biomaterials with promising applications in drug delivery and antimicrobial therapy.
Suraj Kumar, Rishabha Malviya, Sathvik Belagodu Sridhar, Tarun Wadhwa, Javedh Shareef   +4 more
wiley   +1 more source