Quantitative proteomic analysis of the protective effect exerted by alliin on ox-LDL-injured HUVECs [PDF]
Scientific ReportsNatural organic sulfides are predominantly found in cruciferous and liliaceous plants. Among these compounds, alliin—an organic sulfide derived from garlic—has garnered significant attention from researchers due to its potential anti-atherosclerotic ...
Yuan-yuan Tang, De Lv
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Identification and functional characterization of AsWRKY9, a WRKY transcription factor modulating alliin biosynthesis in garlic (Allium sativum L.) [PDF]
BMC BiologyBackground The variations in alliin content are a crucial criterion for evaluating garlic quality and is the sole precursor for allicin biosynthesis, which is significant for the growth, development, and stress response of garlic.
Jiaying Wu +13 more
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Development and Application of a Novel ‘Green’ Antibacterial Black Garlic (Allium sativum)-Based Nanogel in Epidermal Wound Healing§ [PDF]
Food Technology and BiotechnologyResearch background. Black garlic has been reported to have several health-promoting properties compared to fresh, raw garlic. The enzyme alliinase, which converts alliin to allicin, is deactivated at moderately high temperature, thus stripping away the ...
Mariah Sadaf +5 more
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L-Alliin Modulates Brain Region-Specific Neuroinflammatory Responses to Lipopolysaccharide in Diet-Induced Obese Mice [PDF]
Brain SciencesBackground/Objectives: A high-fat diet disrupts metabolic and neuroimmune balance in the brain, making neural tissue more reactive to inflammatory challenges.
Celia González-Castillo +5 more
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S-allyl cysteine and alliin enhance catalase activity and prevent aggregation to counter oxidative stress in alzheimer’s disease [PDF]
Scientific ReportsOxidative stress is a key driver of Alzheimer’s disease (AD), often linked to reduced activity of catalase, a major antioxidant enzyme. In AD, catalase is not only less active but also found as part of harmful protein aggregates with amyloid-β in brain ...
Seemasundari Yumlembam +6 more
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Alliin Induces Reconstitution of Testes Damaged by Estrogen Overstimulation by Regulating Apoptosis [PDF]
Current Issues in Molecular BiologyWe analyzed the effect of alliin on the recovery of mouse testicular function and structure following estradiol treatment as well as on apoptosis regulation. During the cultivation of testicular cells, high-concentration estradiol suppressed Casp-3; PCNA,
Dae-Seung Kim, Min-Jee Oh, Sang-Hwan Kim
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Modulatory L-Alliin Effect on Acute Inflammatory Cytokines in Diet-Induced Obesity Mice [PDF]
MetabolitesBackground/Objectives: The inflammatory response has evolved as a protective mechanism against pathogens and tissue damage. However, chronic inflammation can occur, potentially leading to severe disease.
Daniel Ulises Torres-Reyes +6 more
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Effect of Temperature Conditions on the Physicochemical Quality of Aged Black Garlic [PDF]
FoodsThis study investigates the effects of different temperature conditions on the quality of black garlic (BG) during the aging process. Two temperature protocols were employed: gradual heating and cooling (GHC), where the temperature was slowly raised from
Jung-Hye Shin +3 more
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Chemical analysis of Alliin-Rich Allium sativum (Garlic) extract and its safety evaluation in Drosophila melanogaster [PDF]
Toxicology ReportsGarlic (Allium sativum) has been traditionally valued for its medicinal properties attributed to the presence of organosulfur compounds. Despite its benefits, concerns about herbal extract toxicity have arisen, necessitating safety assessment. This study
Zeniat Emike Oyaluna +6 more
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Parallel analysis of global garlic gene expression and alliin content following leaf wounding
BMC Plant Biology, 2021 Background Allium sativum (garlic) is an economically important food source and medicinal plant rich in sulfides and other protective substances such as alliin, the precursor of allicin biosynthesis. Cysteine, serine and sulfur is the precursor of alliin
Xuqin Yang +11 more
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