Results 1 to 10 of about 5,950 (136)

Allicin, a Natural Antimicrobial Defence Substance From Garlic, Inhibits DNA Gyrase Activity in Bacteria

open access: yesInternational Journal of Medical Microbiology, 2020
Allicin (diallylthiosulfinate) is a potent antimicrobial substance, produced by garlic tissues upon wounding as a defence against pathogens and pests.
Lars Ingo Ole Leichert, Frank Albrecht
exaly   +3 more sources

Pharmacological and Therapeutic Potential of Garlic (Allium sativum): Integrating Phytochemistry, Molecular Mechanisms, and Clinical and Preclinical Evidence. [PDF]

open access: yesChemistryOpen
Garlic bioactive compounds, including organosulfur compounds (allicin, DADS, DATS, and SAC), phenolic compounds, and quercetin, regulate the Nrf2/HO‐1, NF‐κB, PI3K/Akt, and AMPK/eNOS signaling pathways. These actions enhance antioxidant defenses, suppress inflammation, improve metabolic and cardiovascular function, and contribute to reduced blood ...
Bereda G.
europepmc   +2 more sources

Mini-review: The health benefits and applications of allicin [PDF]

open access: yesFrontiers in Pharmacology
Garlic is a perennial plant with a long history of cultivation and medicinal use. As a valuable food additive and spice, garlic contains many nutrients and chemicals. Allicin is a key bioactive organosulfur metabolite derived from garlic bulbs. In recent
Ke-Qian Chen   +3 more
doaj   +2 more sources

Allicin promotes autophagy and ferroptosis in esophageal squamous cell carcinoma by activating AMPK/mTOR signaling

open access: yesHeliyon, 2022
The antitumor effects of allicin have been demonstrated in various cancers. However, whether allicin improves esophageal squamous cell carcinoma (ESCC) has not yet been explored. The present study aimed to explore the function and underlying mechanism of
Zhanfang Guo, Yanjiao Zhang
doaj   +1 more source

Allicin suppresses human glioblastoma cell growth by inducing cell cycle arrest and apoptosis, and by promoting autophagy [PDF]

open access: yesArchives of Biological Sciences, 2020
Glioblastoma is the most aggressive cancer that occurs in the brain and spinal cord. In the present study, we investigated the effect of allicin, an organosulfur compound obtained from garlic (Allium sativum), on glioblastoma cell growth.
Weeranantanapan Oratai   +3 more
doaj   +1 more source

The antimicrobial and antibiofilm properties of allicin against Candida albicans and Staphylococcus aureus – A therapeutic potential for denture stomatitis

open access: yesSaudi Dental Journal, 2021
The objective of this study is to determine the therapeutic efficacy of allicin against Candida albicans (C. albicans) and Staphylococcus aureus (S. aureus), the common etiological agents for denture stomatitis (DS). The minimum inhibitory concentration (
Mukarramah Zainal   +3 more
doaj   +1 more source

Thermal degradation, antioxidant and antimicrobial activity of the synthesized allicin and allicin incorporated in gel [PDF]

open access: yesHemijska Industrija, 2010
The main carriers of the pharmacological activity of garlic (Allium sativum L.) are organic sulfur compounds, the most important among them being allicin, a sulfenic acid thioester, or allylthiosulfonate.
Ilić Dušica P.   +4 more
doaj   +1 more source

Fabrication and Antibacterial Performance of Pea Protein Isolate/Pullulan/Allicin Composite Electrospun Nanofibers [PDF]

open access: yesShipin Kexue, 2023
Using pea protein isolate (PPI) and pullulan (PUL) as raw materials and allicin (AC) as an antibacterial substance, nanofiber materials were prepared by electrospinning technology.
JIA Xiwen, LIU Jiuyang, WANG Jingjie, LIU Qian, WANG Hao, KONG Baohua, WANG Hui
doaj   +1 more source

Co-Application of Allicin and Chitosan Increases Resistance of Rosa roxburghii against Powdery Mildew and Enhances Its Yield and Quality

open access: yesAntibiotics, 2021
Powdery mildew, caused by Sphaerotheca sp., annually causes severe losses in yield and quality in Rosa roxburghii production areas of southwest China.
Jiaohong Li   +5 more
doaj   +1 more source

Allicin Improves Intestinal Epithelial Barrier Function and Prevents LPS-Induced Barrier Damages of Intestinal Epithelial Cell Monolayers

open access: yesFrontiers in Immunology, 2022
Gut barrier disruption is the initial pathogenesis of various diseases. We previously reported that dietary allicin improves tight junction proteins in the endoplasmic reticulum stressed jejunum.
Jingxia Gao   +12 more
doaj   +1 more source

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