Results 21 to 30 of about 5,950 (136)

Allicin inhibits HBV replication through the HBV promoter SP2 [PDF]

Jichu yixue yu linchuang
Objective To investigate the effect of allicin on the replication of hepatitis B virus (HBV) and to preliminarily elucidate its underlying molecular mechanisms.
LU Lili, ZHU Xilin, WU Xiaopan, LIU Ying
doaj   +1 more source

Antifungal Activity and Potential Action Mechanism of Allicin against Trichosporon asahii

Microbiology Spectrum, 2023
Trichosporon asahii is an emerging opportunistic pathogen that causes potentially fatal disseminated trichosporonosis. The global prevalence of coronavirus disease 2019 (COVID-19) poses an increasing fungal infection burden caused by T. asahii.
Xin Yang, Shuang Bai, Jiamin Wu, Yunlong Fan, Yuekun Zou, Zhikuan Xia, Junhong Ao, Tong Chen, Mingwang Zhang, Rongya Yang   +9 more
doaj   +1 more source

Effect and mechanism of allicin combined with 5-fluorouracil on proliferation and apoptosis of the MEC-1 cell line in mucoepidermoid carcinoma

口腔疾病防治, 2020
Objective To investigate the effect and mechanism of allicin combined with 5-FU on proliferation inhibition and apoptosis of the mucoepidermoid carcinoma MEC-1 cell line in mucoepidermoid carcinoma in order to provide the corresponding basis for ...
WU Fayin, XU Haili
doaj   +1 more source

Genetic and molecular characterization of multicomponent resistance of Pseudomonas against allicin

Life Science Alliance, 2020
A pseudomonad isolated from garlic has multiple copies of genes on three genomic islands that confer resistance to allicin, a secondary plant product and defense substance that causes disulfide stress.
Jan Borlinghaus, Anthony Bolger, Christina Schier, Alexander Vogel, Björn Usadel, Martin CH Gruhlke, Alan J Slusarenko   +6 more
doaj   +1 more source

Allicin disrupts cardiac Cav1.2 channels via trafficking

Pharmaceutical Biology, 2019
Context: Allicin is a potential antiarrhythmic agent. The antiarrhythmic properties of allicin rely on its blockade of various cardiac ion channels.
Dan Han, Lingping Xu, Peng Liu, Yingying Liu, Chaofeng Sun, Yanrong Yin   +5 more
doaj   +1 more source

Allium sativum, a Natural and Pharmaco‐Remedial Panacea for Entero‐Gastritis, Antibiocidal/Dysbiogenesis, and Systemic Health Relevance

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Natural Pharmaco‐remedial impacts of Allium sativum on Systemic health. ABSTRACT Arising from the emergence of diverse difficult‐to‐treat health cases, alterative‐therapeutic strategies have become a potential way forward for management/control. In traditional Chinese medicine (TCM), various plant materials have been sourced as alterative‐therapeutic ...
Patience O. Adomi, Bright E. Igere, Anthony J. Anozie, Oghenenyore A. Ohwokevwo   +3 more
wiley   +1 more source

Evaluate the stability of synthesized allicin and its reactivity with endogenous compounds in garlic

npj Science of Food
The study aimed to prepare allicin in large quantities and evaluate the effects of different conditions and endogenous substances (polyphenols and free amino acids) in garlic on its stability. The optimized synthesis conditions of allicin (DADS:HAc = 2:9,
Shanshan Zhou, Xiaoying Yan, Xuguang Qiao, Zhichang Qiu, Weihe Zhu, Xiaoming Lu, Zhenjia Zheng, Bin Zhang   +7 more
doaj   +1 more source

Allicin, an Antioxidant and Neuroprotective Agent, Ameliorates Cognitive Impairment

Antioxidants, 2021
Allicin (diallylthiosulfinate) is a defense molecule produced by cellular contents of garlic (Allium sativum L.). On tissue damage, the non-proteinogenic amino acid alliin (S-allylcysteine sulfoxide) is converted to allicin in an enzyme-mediated process ...
Muhammad Shahid Nadeem, Imran Kazmi, Inam Ullah, Khushi Muhammad, Firoz Anwar   +4 more
doaj   +1 more source

Nutrition and Metabolic Diseases: A Systematic Review of Functional Foods, Medicinal Plants, Phytochemicals, Bioactive Compounds and Nutrients Effective Against Metabolic Diseases

Food Chemistry International, EarlyView.
The study demonstrates how functional foods, medicinal plants, phytochemicals, bioactive compounds and essential nutrients combat metabolic diseases. It highlights their mechanisms, including antioxidant, anti‐inflammatory, insulin‐sensitising, lipid‐regulating, gut microbiota‐modulating and mitochondrial‐enhancing effects, leading to improved ...
Chinaza Godswill Awuchi, Sana Noreen, Sonia Morya   +2 more
wiley   +1 more source

Computational study of the therapeutic properties of allicin and its nanocomplexes using DFT and molecular docking techniques

Scientific Reports
This study investigated the anti-inflammatory, anticancer, antiviral, and antibacterial effects of allicin and its complexes (Allicin/C₂₄, Allicin/B₁₂N₁₂, and Allicin/Al₁₂N₁₂) using advanced computational techniques such as Density Functional Theory (DFT)
E. S. Mozafari, Mohammad T. Baei, E. Tazikeh Lemeski   +2 more
doaj   +1 more source