Results 11 to 20 of about 1,573 (154)

Release test of alliin/alliinase double-layer tablet by HPLC—Allicin determination

Journal of Pharmaceutical Analysis, 2013
A simple, precise and accurate method was developed and validated for the determination of allicin release from alliin/alliinase double-layer tablets. According to Appendix XC II of Chinese Pharmacopoeia 2010 edition Volume II, a small glass-method was ...
Yan Liang, Jing-Jing Zhang, Qi-Bing Zhang, Zhong-Xia Wang, Zong-Ning Yin, Xin-Xia Li, Jian Chen, Li-Ming Ye   +7 more
doaj   +3 more sources

Garlic γ-glutamyl transpeptidases that catalyze deglutamylation of biosynthetic intermediate of alliin [PDF]

Frontiers in Plant Science, 2015
S-Alk(en)yl-L-cysteine sulfoxides are pharmaceutically important secondary metabolites produced by plants that belong to the genus Allium. Biosynthesis of S-alk(en)yl-L-cysteine sulfoxides is initiated by S-alk(en)ylation of glutathione, which is ...
Naoko eYoshimoto, Ayami eYabe, Yuka eSugino, Soichiro eMurakami, Niti eSai-ngam, Shin-ichiro eSumi, Tadamitsu eTsuneyoshi, Kazuki eSaito, Kazuki eSaito   +8 more
doaj   +3 more sources

The Nutraceutical Alliin From Garlic Is a Novel Substrate of the Essential Amino Acid Transporter LAT1 (SLC7A5)

Frontiers in Pharmacology, 2022
The plasma membrane transporter LAT1 (SLC7A5) is a crucial player for cell homeostasis because it is responsible for providing cells with essential amino acids and hormones.
Raffaella Scanga, Mariafrancesca Scalise, Filomena Rovella, Teresa Maria Rosaria Regina, Michele Galluccio, Cesare Indiveri, Cesare Indiveri   +6 more
doaj   +1 more source

Onion (<i>Allium cepa L</i>.) Organosulfur Compounds: From Traditional Use to Modern Pharmacological Insights. [PDF]

Food Sci Nutr
This review systematically examines the chemical diversity, extraction methods, and pharmacological activities of organosulfur compounds (OSCs) in onions. Key mechanisms include lipid metabolism regulation, anti‐bacterial and anti‐tumor effects, hypoglycemic activity, and anti‐asthmatic potential.
Tang Y, Lv, Tao Y.
europepmc   +2 more sources

Integrated Transcriptomics and Metabolomics Reveal the Mechanism of Alliin in Improving Hyperlipidemia

Foods, 2023
This research aims to assess the anti-hyperlipidemia effects of alliin in vivo and its potential mechanisms through transcriptomics and metabolomics analysis.
Min Zhang, Xiaoying Zou, Yixuan Du, Zhuangguang Pan, Fangqing He, Yuanming Sun, Meiying Li   +6 more
doaj   +1 more source

Evaluation of Medicinal Quality of Garlic Based on Principal Component Analysis

Shipin gongye ke-ji, 2023
To compare and analyze the medicinal quality of garlic, a garlic medicinal quality evaluation system was established. Moisture, ash, water-soluble extract, diallyl trisulfide content, alliin content, allicin content and alliinase activity were screened ...
Xiaoxia HU, Lijuan DENG, Ruiting LIU, Rongmei SHI   +3 more
doaj   +1 more source

Combined Effects of Amino Acids in Garlic and Buna-Shimeji (Hypsizygus marmoreus) on Suppression of CCl₄-Induced Hepatic Injury in Rats

Foods, 2021
The combination of the garlic-derived amino acid, S-allyl-l-cysteine sulfoxide (ACSO), and ornithine or arginine on CCl4-induced hepatic injury was examined.
Yusuke Yamaguchi, Yushi Hirata, Takeshi Saito, Hitomi Kumagai   +3 more
doaj   +1 more source

Comparison of Alliin Recovery from Allium sativum L. Using Soxhlet Extraction and Subcritical Water Extraction

ChemEngineering, 2022
Garlic (Allium sativum L.) is an herbaceous plant and is recognised for its numerous medicinal and culinary properties, and it is used in diverse food preparations for its characteristic flavour and aroma.
Ahmad Syahmi Zaini, Nicky Rahmana Putra, Zuhaili Idham, Azrul Nurfaiz Mohd Faizal, Mohd Azizi Che Yunus, Hasmadi Mamat, Ahmad Hazim Abdul Aziz   +6 more
doaj   +1 more source

Virtual Screening of Phytochemicals From Medicinal Plants as Promising PDE5 Inhibitors Against Erectile Dysfunction. [PDF]

Food Sci Nutr
Phytochemicals from Algerian medicinal plants were virtually screened as potential phosphodiesterase‐5 (PDE5) inhibitors for erectile dysfunction therapy. Drug‐likeness and toxicity analyses identified catechin, ellagic acid, and rosmarinic acid as safe, bioavailable candidates.
Boudou F, Berkane A, Belakredar A, Keziz A, Alsaeedi H, Murray BA, Bechelany M, Barhoum A.   +7 more
europepmc   +2 more sources

STUDI IN SILICO POTENSI SENYAWA ALLIIN BAWANG PUTIH (Allium sativum) SEBAGAI INHIBITOR DPP-4 PADA DIABETES MELLITUS

Jurnal Ilmiah Medicamento, 2018
Diabetes mellitus (DM) merupakan penyakit gangguan metabolisme glukosa yang dicirikan dengan gangguan sekresi dan resistensi insulin. Jalur pengobatan DM baru pada sistem increatin dengan penghambatan terhadap DPP-4 telah dikembangkan dan terbukti ...
Martina Kurnia Rohmah
doaj   +3 more sources