Results 81 to 90 of about 2,550 (172)

Implementation of soluble CD38 in blood crossmatching for patients on anti‐CD38 therapy: A single‐center experience

open access: yesTransfusion, EarlyView.
Abstract Background Human monoclonal (MoAb) anti‐CD38 antibodies, such as daratumumab, are used to treat diseases such as multiple myeloma. Because red blood cells (RBCs) express CD38, these MoAbs interfere with antibody screening and crossmatching in blood banks.
Ayda Javanbakht   +3 more
wiley   +1 more source

Endothelial Dysfunction in Kidney Transplantation

open access: yesFrontiers in Immunology, 2018
Kidney transplantation entails a high likelihood of endothelial injury. The endothelium is a target of choice for injury by ischemia-reperfusion, alloantibodies, and autoantibodies. A certain degree of ischemia-reperfusion injury inevitably occurs in the
Héloïse Cardinal   +7 more
doaj   +1 more source

Screening of blood donors for erythrocyte alloantibodies

open access: yesHematology, 2012
To assess the prevalence of the anti-red blood cell antibodies in the donor population of Delhi.This prospective study was conducted in Regional Blood Transfusion Centre (RBTC), Lady Hardinge Medical College (LHMC) and associated hospitals from March 2010 to March 2011.
Sangeeta, Pahuja   +4 more
openaire   +2 more sources

A functionally distinct HPA‐1a‐specific alloantibody associated with fetal/neonatal alloimmune thrombocytopenia that activates platelets via FcγRIIa

open access: yesTransfusion, EarlyView.
Abstract Background Fetal/neonatal alloimmune thrombocytopenia (FNAIT) is caused by maternal alloantibodies directed against fetal platelet antigens, most commonly human platelet antigen‐1a (HPA‐1a). These antibodies mediate platelet destruction and can lead to fetal and neonatal thrombocytopenia severe enough to cause life‐threatening organ bleeds ...
Huiying Zhi   +9 more
wiley   +1 more source

COL4A5 gene deletion and production of post-transplant anti-α3(IV) collagen alloantibodies in Alport syndrome [PDF]

open access: yes, 1994
COL4A5 gene deletion and production of post-transplant anti-α3(IV) collagen alloantibodies in Alport syndrome. Mutations in the COL4A5 gene encoding the α5(IV) chain of type IV collagen have been implicated as the primary defect in X-linked Alport ...
Kalluri, Raghuram   +5 more
core   +1 more source

Case reports: red blood cell autoantibodies mimicking alloantibodies.

open access: yes, 1991
The phenomenon of autoantibodies mimicking alloantibodies is rare and challenging.
Clarke, A, Domen, R E
core   +1 more source

Factor VIII inhibitors demonstrate type I or type II kinetics in high‐titre alloantibodies and autoantibodies

open access: yesClinical and Translational Discovery, Volume 6, Issue 5, October 2026.
The inhibitor kinetics type cannot be used by itself to determine auto‐ versus allo‐anti‐FVIII antibody type. To characterise inhibitor kinetics in inherited haemophilia A (HA) and acquired haemophilia A (AHA) patients in our centre, results show that inhibitors for both HA alloantibodies and AHA autoantibodies may exhibit either type I or type II ...
Cuicui Qiao   +10 more
wiley   +1 more source

Clinical Significance of Alloantibodies in Hand Transplantation: A Multicenter Study

open access: yes, 2019
Clinical Significance of Alloantibodies in Hand Transplantation: A Multicenter ...
C Höhnke (13534363)   +25 more
core  

The prevalence of erythrocyte alloimmunization in clinical practice: A hospital-based study

open access: yesIraqi Journal of Hematology
BACKGROUND: One of the complications of blood transfusion is the development of red cell alloimmunization. Little published literature on the prevalence and actual significance of red cell alloantibodies among nonregularly transfused patients and the ...
Inas Bashar Faisal   +4 more
doaj   +1 more source

Antigen–antibody complex density and antibody-induced HLA protein unfolding influence Fc-mediated antibody effector function

open access: yesFrontiers in Immunology
Donor-specific antibodies (DSAs) targeting mismatched human leukocyte antigen (HLA) molecules are one of the principal threats to long-term graft survival in solid organ transplantation.
Tanusya Murali Murali   +16 more
doaj   +1 more source

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