Results 61 to 70 of about 2,550 (172)

Assessment of Unexpected (Non-ABO) Red Blood Cell Antibodies and Their Associated Clinical Conditions Among Patients and Blood Donors Attending University Teaching Hospital of Kigali (CHUK) and Rwanda Blood Transfusion Division

Advances in Hematology
Unexpected antibodies can cause hemolytic conditions. Therefore, screening for unexpected antibodies is essential for safe transfusion. The study was conducted at Rwanda Blood Transfusion Division and University Teaching Hospital of Kigali to assess ...
Jean Baptiste Niyibizi, Daniel Seifu, Chelsey Geurkink, Erica Formiller, Thomas Muyombo, Christopher Gashaija, Henri Desire Uwayo, Gilbert Uwizeyimana, Laurie Gillard   +8 more
doaj   +1 more source

Red cell alloimmunization in multitransfused hepatobiliary patients at hospital Selayang

Asian Journal of Transfusion Science
BACKGROUND: Transfusion support is vital for the management of patients with hepatobiliary disease. Repeated blood transfusions increase the risk of alloimmunization, i.e., the development of alloantibodies, which might lead to difficulties in blood ...
Prasanthini Nahendran, Siti Balkis Budin, Nur Zakiah Mohd Saat, Mohd Faeiz Yusop, Tengku Norita Tengku Yazid, Nur Najmi Mohamad Anuar   +5 more
doaj   +1 more source

A global survey of blood transfusion practices for patients with sickle cell disease

Transfusion, EarlyView.
Abstract Background Sickle cell disease (SCD) affects over 7 million people globally, with blood transfusion remaining a cornerstone of management. However, contemporary transfusion practices across diverse settings remain poorly characterized. We evaluated global transfusion practices for patients with SCD to identify gaps and inform resource ...
Jeremy W. Jacobs, Arwa Z. Al‐Riyami, Jeannie Callum, Meghan Delaney, David Daniel, Jenny White, Christopher Bocquet, Mohammed Farouk, Claude Tayou, Chinelo P. Onyenekwu, Kristina Prus, Divjot Singh Lamba, Julie Makani, Quentin Eichbaum, Luiz Amorim, Silvano Wendel, France Pirenne, Vernon Louw, Evan M. Bloch   +18 more
wiley   +1 more source

Systematic approach in identification and management of multiple alloantibody: A case of triple alloantibody

Global Journal of Transfusion Medicine, 2019
Alloimmunization is an adverse consequence of exposition to red blood cell antigens through transfusion, pregnancy, or transplantation. Alloimmunization to red cell antigens creates problem not only in immunohematological testing but also causes difficulty in finding compatible blood for those patients who develop multiple alloantibodies. Moreover, the
Samrat Thapa, Latha Jagannathan, Ankit Mathur, T V Kumar Reddy, Santanu Chakraborty   +4 more
openaire   +2 more sources

Interpreting antibody identification tests with large language models: Critical role of tabular data formatting

Transfusion, EarlyView.
Abstract Background Antibody identification testing is essential for preventing hemolytic transfusion reactions from unexpected red cell antibodies. Although automated interpretation is desirable to improve efficiency and consistency, conventional algorithmic approaches show limited accuracy, particularly in complex cases.
Jiwoo Lee, Yousun Chung, Dae‐Hyun Ko, Eun Young Song, Hyungsuk Kim   +4 more
wiley   +1 more source

Antibody of Undetermined Specificity - The Eyes Do Not See What the Mind Does Not Know: Are You Dealing with a Low Prevalence Red Blood Cell Antigens?

Global Journal of Transfusion Medicine
For identification (ID) of irregular antibodies, a standard antibody identification (AI) panel consisting of 18 mandatory antigens expressed on reagent red blood cells is used. The phenotype for each antigen is listed on a red cell antigram provided with
Rasika Dhawan Setia, Gunjan Bhardwaj, Mitu Dogra, Amena Ebadur Rahman   +3 more
doaj   +1 more source

Breakthrough Hemolysis in Paroxysmal Nocturnal Hemoglobinuria: Mechanistic Insights and Management Strategies

Transfusion, EarlyView.
Abstract Background Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem cell disorder caused by somatic mutations in the PIGA gene, resulting in loss of glycosylphosphatidylinositol (GPI)‐anchored proteins, including the complement regulatory proteins, CD55 and CD59.
Ganesh Raman, Meghana Vivek, Rida Hasan, Siobán Keel, Laura Connelly‐Smith   +4 more
wiley   +1 more source

Occurrence of anti-D alloantibodies among pregnant women in Kasese District, Western Uganda

, 2015
Yona Mbalibulha,1 Enoch Muwanguzi,1 Godfrey R Mugyenyi,2 Bernard Natukunda1 1Department of Medical Laboratory Sciences, 2Department of Obstetrics and Gynecology, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda ...
Natukunda B, Mbalibulha Y, Muwanguzi E, Mugyenyi GR   +3 more
core  

Retrospective Study on Prevalence, Specificity, Sex, and Age Distribution of Alloimmunization in Two General Hospitals in Athens

Turkish Journal of Hematology, 2020
Objective: Blood transfusion is a common lifesaving treatment but it is often complicated with alloimmunization. Previously studies in Greece have concentrated on alloimmunization in multiply transfused thalassemic patients or antenatal women.
Marianna Politou, Serena Valsami, Georgios Dryllis, Maria Christodoulaki, Christina Cheropoulou, Abraham Pouliakis, Maria Baka, Konstantinos Stamoulis   +7 more
doaj   +1 more source

Pretransfusion testing interference profile of IMC‐002: A novel anti‐CD47 monoclonal antibody engineered for minimized red cell binding

Transfusion, EarlyView.
Abstract Background CD47‐targeted agents can interfere with pretransfusion testing due to CD47 expression on red blood cells (RBCs). IMC‐002 is a novel anti‐CD47 human IgG4 monoclonal antibody engineered to minimize RBC binding; however, its interference profile during pretransfusion testing remains poorly characterized.
Tae‐Shin Kim, Jae Hyeon Park, Yousun Chung, Dae‐Hyun Ko, Seon Young Kim, Hyungsuk Kim   +5 more
wiley   +1 more source