Results 61 to 70 of about 5,225 (173)

TOMM40 suppression promotes neuronal cholesterol imbalance and molecular and behavioral phenotypes of Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION While the apolipoprotein E (APOE) ε4 allele is a major risk factor for Alzheimer's disease (AD), the role of translocase of outer mitochondrial membrane 40 (TOMM40)—an adjacent gene involved in mitochondrial protein import—is not known. METHODS Human brain tissue, human induced pluripotent stem cell–derived neurons (iNeurons), and
Neil V. Yang   +8 more
wiley   +1 more source

The stationarity hypothesis: an allocentric criterion in visual perception

open access: yesVision Research, 2001
Having long considered that extraretinal information plays little or no role in spatial vision, the study of structure from motion (SfM) has confounded a moving observer perceiving a stationary object with a non-moving observer perceiving a rigid object undergoing equal and opposite motion.
Wexler, Mark   +2 more
openaire   +3 more sources

Structure, Dynamics, and Neural Codes in a Bat Social Network

open access: yesAnnals of the New York Academy of Sciences, Volume 1558, Issue 1, April 2026.
We studied group formation in highly social Egyptian fruit bats housed in a laboratory cave. Using advanced tracking, videography, and wireless single‐unit neural recordings, we showed that social networks evolved dynamically and then stabilized, with social hierarchy shaping behaviors such as food access and sleeping arrangements.
Saikat Ray, Liora Las, Nachum Ulanovsky
wiley   +1 more source

Spatial task context makes short-latency reaches prone to induced Roelofs illusion

open access: yesFrontiers in Human Neuroscience, 2014
The perceptual localization of an object is often more prone to illusions than an immediate visuomotor action towards that object. The induced Roelofs effect (IRE) probes the illusory influence of task-irrelevant visual contextual stimuli on the ...
Bahareh eTaghizadeh   +4 more
doaj   +1 more source

The Effectiveness of Home-Based Training Software Designed to Influence Strategic Navigation Preferences in Healthy Subjects

open access: yesFrontiers in Human Neuroscience, 2020
One approach to the rehabilitation of navigation impairments is to train the use of compensatory egocentric or allocentric navigation strategies.
Milan N. A. van der Kuil   +4 more
doaj   +1 more source

Low-Resolution Place and Response Learning Capacities in Down Syndrome

open access: yesFrontiers in Psychology, 2018
Down syndrome (DS), the most common genetic cause of intellectual disability, results from the partial or complete triplication of chromosome 21. Individuals with DS are impaired at using a high-resolution, allocentric spatial representation to learn and
Mathilde Bostelmann   +6 more
doaj   +1 more source

Evidence for allocentric boundary and goal direction information in the human entorhinal cortex and subiculum

open access: yesNature Communications, 2019
In rodents, cells in the medial entorhinal cortex and subiculum are known to encode the allocentric direction to nearby walls and boundaries. Here, using fMRI the authors show that this is also true in humans, with allocentric boundary direction being ...
J. P. Shine   +3 more
doaj   +1 more source

Perspective: Assessing the Flexible Acquisition, Integration, and Deployment of Human Spatial Representations and Information

open access: yesFrontiers in Human Neuroscience, 2018
Studying human spatial navigation in the lab can be challenging, particularly when including non-invasive neural measures like functional magnetic resonance imaging (fMRI) and scalp encephalography (EEG). While there is broad consensus that human spatial
Michael J. Starrett   +6 more
doaj   +1 more source

Allocentric and egocentric spatial representations coexist in rodent medial entorhinal cortex

open access: yesNature Communications
Successful navigation relies on reciprocal transformations between spatial representations in world-centered (allocentric) and self-centered (egocentric) frames of reference.
Xiaoyang Long   +4 more
doaj   +1 more source

Neuro-anatomical dissections of unilateral visual neglect symptoms: ALE meta-analysis of lesion-symptom mapping

open access: yesFrontiers in Human Neuroscience, 2012
Unilateral visual neglect is commonly defined as impaired ability to attend to stimuli presented on the side of visual space contralateral to the brain lesion. However, behavioural analyses indicate that different neglect symptoms can dissociate.
Magdalena eChechlacz   +2 more
doaj   +1 more source

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