Results 101 to 110 of about 32,744 (263)

Tetrodotoxin suppresses thermal hyperalgesia and mechanical allodynia in a rat full thickness thermal injury pain model

, 2015
Margaux M. Salas, Matthew K. McIntyre, Lawrence N. Petz, Walter Korz, Donald Wong, John L. Clifford   +5 more
openalex   +1 more source

Capsaican-evoked Mechanical Allodynia and Hyperalgesia Cross-nerve Territories  [PDF]

, 1997
Leroy D. Vandam
openalex   +1 more source

Impaired WNT3/IGF‐1 Signaling in Dorsal Dentate Gyrus Contributes to Chronic Pain‐Related Cognitive Impairment

CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
Schematic diagram depicting the mechanism of SNI‐induced comorbidity of pain and cognition decline. SNI increased TNFα release in the dorsal DG (1); TNFα trigger a “double hit” to dorsal DG homeostasis: On the one hand, TNFα induced IGF‐1 resistance in granule neuron.
Yajie An, Ying Wu, Xiangyong Li, Taihe Zhou, Heming Liu, Yao Xiao, Wenyu Lai, Yuxin Qiu, Xuhong Wei   +8 more
wiley   +1 more source

Reversal of Fentanyl‐Induced Respiratory Depression in Healthy Subjects by Intramuscular Nalmefene Administered by Auto‐Injector Versus Intranasal Naloxone

The Journal of Clinical Pharmacology, Volume 65, Issue 12, Page 1661-1675, December 2025.
Abstract As illegally made fentanyl and congeners continue to drive overdose deaths in the US, experts have called for stronger and longer‐lasting antagonists. A randomized, 4‐period, 2‐treatment crossover replicate‐design study in healthy moderately‐experienced opioid users (n = 24) evaluated the reversal of opioid‐induced respiratory depression (OIRD)
Alessandra Cipriano, Ellie He, Manjunath Shet, Glen Apseloff, Stephen C. Harris   +4 more
wiley   +1 more source

Study of conditions to evaluate light hypersensitivity in a light–dark box using a mouse model and a mydriatic

Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.
Abstract Aim The pathophysiology and treatment of sensory hypersensitivity remain unclear. This study aimed to identify a simple behavioral analysis device and animal model evaluating glare sensitivity and to test the effects of psychotropic drugs using this device.
Shogo Hirota, Leo Gotoh, Reo Hayashi, Yoshikazu Kitai, Hideki Matsuoka, Masato Masuda, Hiroaki Kawasaki, Hikaru Hori   +7 more
wiley   +1 more source

Regenerating the Senses: Stem Cell‐Derived Sensory Neurons and Functional Genomics in Neurological Disorders

Sensory Neuroscience, Volume 1, Issue 3, December 2025.
ABSTRACT Sensory neuron disorders, such as peripheral neuropathies and trigeminal neuralgia, cause chronic pain and sensory dysfunction; however, regenerative treatments are limited. Human pluripotent stem cells (hPSCs) provide a powerful platform to model these diseases by generating functional sensory neuron subtypes, including nociceptors and ...
Pushpanathan Muthuirulan, Avanthika Nityanand, Anjali Pandit, Vaishnavi Gururajan   +3 more
wiley   +1 more source

Metabolic resilience governs sex-specific pain recovery during hormonal aging: a multi-omics study of neuropathy in mice

Frontiers in Pain Research
IntroductionBiological aging and sex interact to shape systemic metabolism, yet their role in chronic pain resolution remains unexplored. We hypothesized that metabolic resilience—the ability to flexibly switch fuel sources and maintain energy ...
Sara Marinelli, Claudia Rossi, Luisa Pieroni, Luisa Pieroni, Giacomo Giacovazzo, Giacomo Giacovazzo, Valentina Vacca, Federica De Angelis, Ilaria Cicalini, Ilaria Cicalini, Valentina Mastrorilli, Chiara Parisi, Zuleyha Nihan Yurtsever, Domenico Ciavardelli, Roberto Coccurello, Roberto Coccurello   +15 more
doaj   +1 more source

Long‐term outcome of presumptive idiopathic hyperesthesia syndrome in a dog treated with fluoxetine

Veterinary Record Case Reports, Volume 13, Issue 4, December 2025.
Abstract A 9‐year‐old, 10 kg, male, neutered, mixed‐breed dog was evaluated for a history of daily episodes of thoracic and lumbar hair horripilation with potential hypersensitivity and discomfort for at least 1 year, as reported by the owner. Dermatological disease was ruled out.
Claudia Pauciulo, Antonella Gallucci
wiley   +1 more source

rTMS in the management of allodynia from brachial plexus injuries

, 2012
Federica Bertolucci, Chiara Fanciullacci, Bruno Rossi, Carmelo Chisari   +3 more
openalex   +2 more sources

Lercanidipine alleviates hyperalgesia and allodynia in Rodent Model of paclitaxel induced neuropathy [PDF]

, 2015
Amitava Chakrabarti, S. Shivabasappa, Debasish Hota, Uma Nahar Saikia   +3 more
openalex   +1 more source