Results 101 to 110 of about 66,158 (349)

Apoptotic gene expression in neuropathic pain [PDF]

open access: yes, 2008
Pain initiated or caused by a primary lesion or dysfunction in the nervous system is defined as neuropathic pain. It results from direct injury to nerves in the peripheral or central nervous system and is associated with several clinical symptoms ...
Annalucia Migliozzi   +6 more
core   +2 more sources

Beyond Pain Relief: Unveiling the Multifaceted Impact of Anti-CGRP/R mAbs on Comorbid Symptoms in Resistant Migraine Patients

open access: yesBiomedicines
The study aimed to evaluate the effects of monoclonal antibodies (mAbs) acting on the calcitonin gene-related peptide (CGRP) or its receptor (anti-CGRP/R mAbs) on migraine comorbidities of depression, anxiety, and fatigue in patients resistant to ...
Alessandra Della Vecchia   +7 more
doaj   +1 more source

Thermo-Sensitive TRP Channels: Novel Targets for Treating Chemotherapy-Induced Peripheral Pain

open access: yesFrontiers in Physiology, 2017
Abnormal Ca2+ channel physiology, expression levels, and hypersensitivity to heat have been implicated in several pain states following treatment with chemotherapeutic agents.
Mustafa Nazıroğlu, Nady Braidy
doaj   +1 more source

Allodynia and hyperalgesia: review

open access: yesPain medicine, 2018
The main purpose was to highlight the problem of hyperalgesia and allodynia. Main anatomic structures, which participate in nociception were mentioned in this article, with pathologic and pathophysiologic changes, that can be caused by hyperalgesia and allodynia.
Dmytriiev, K. D.   +2 more
openaire   +4 more sources

Genetically‐targeted control of the spinal cord and peripheral nervous system

open access: yesJournal of Intelligent Medicine, EarlyView.
Application of genetically‐targeted stimulation for treating diseases or injuries outside the brain. Optogenetic and chemogenetic systems have been developed for dysfunction in the cochlea, spinal cord, dorsal root ganglia (DRGs), peripheral nerves, lower urinary tract, and enteric nervous system (ENS). Created with Biorender.com.
Anakaren Romero Lozano   +3 more
wiley   +1 more source

Genitofemoral neuralgia : adding to the burden of chronic vulvar pain [PDF]

open access: yes, 2015
The vulva is a particularly common locus of chronic pain with neuropathic characteristics that occurs in women of any age, though most women with neuropathic type chronic vulvar pain will remain undiagnosed even following multiple physician visits. Here,
De Muynck, Martine   +2 more
core   +2 more sources

Dietary Supplementation with Palmitoyl-Glucosamine Co-Micronized with Curcumin Relieves Osteoarthritis Pain and Benefits Joint Mobility

open access: yesAnimals, 2020
Chronic mixed pain and orthopedic dysfunction are the most frequently associated consequences of canine osteoarthritis (OA). An unmet need remains for safe and effective therapies for OA.
Enrico Gugliandolo   +10 more
doaj   +1 more source

Lack of evidence for central sensitization in idiopathic, non-traumatic neck pain : a systematic review [PDF]

open access: yes, 2015
Background: Chronic neck pain is a common problem with a poorly understood pathophysiology. Often no underlying structural pathology can be found and radiological imaging findings are more related to age than to a patient's symptoms.
Bramer, Wichor   +9 more
core   +1 more source

Riluzole prevents oxaliplatin-induced cold allodynia via inhibition of overexpression of transient receptor potential melastatin 8 in rats

open access: yesJournal of Pharmacological Sciences, 2018
Oxaliplatin causes acute cold hypersensitivity in most patients. We previously reported oxalate derived from oxaliplatin induced cold allodynia via overexpression of transient receptor potential melastatin 8 (TRPM8) in the dorsal root ganglion (DRG) in ...
Shota Yamamoto   +3 more
doaj  

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