Results 121 to 130 of about 34,712 (269)
Robust spinal neuroinflammation mediates mechanical allodynia in Walker 256 induced bone cancer rats [PDF]
, 2012 Qi‐Liang Mao‐Ying +6 more
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Mechanisms for the allodynia caused by complementanaphylatoxin C5a in mice
, 2022 Kazuki Tajima
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The Journal of Physiology, EarlyView.Abstract figure legend We tested the hypothesis that cAMP binding to HCN2 channels in nociceptors is a causal driver of neuropathic pain by using TRIP8bnano, a synthetic peptide we previously developed as a selective antagonist of cAMP in HCN channels. TRIP8bnano effectively abolishes cAMP potentiation of HCN2 currents in small‐diameter DRG neurons and
Santiago I. Loya‐Lopez +7 more
wiley +1 more source
ABHD6 and MAGL control 2-AG levels in the PAG and allodynia in a CSD-induced periorbital model of headache [PDF]
, 2023 Erika Liktor‐Busa +7 more
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Trafficking and potentiation of Nav1.7 and Nav1.8 channels are mediated by IQGAP1
The Journal of Physiology, EarlyView.Abstract figure legend IQGAP1 binds to the voltage‐gated Nav1.7 and Nav1.8 channels and TRPA1 channels in sensory neurons. Inflammatory mediators (IM), including PGE2 and TNFα, released during nerve injury and inflammation activate intracellular signalling messengers such as PKA, p38 MAPK and Cdc42 through their respective receptors.
Xuming Zhang +2 more
wiley +1 more source
Butyrate inhibits visceral allodynia and colonic hyperpermeability in rat models of irritable bowel syndrome [PDF]
, 2019 Tsukasa Nozu +4 more
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The Journal of Physiology, EarlyView.Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise +2 more
wiley +1 more source
Brain Hsp90 Inhibition Mitigates Facial Allodynia in a Rat Model of CSD Headache and Upregulates Endocannabinoid Signaling in the PAG [PDF]
Seph M. Palomino +5 more
openalex +1 more source
Quantitative Assessment of Mechanical Allodynia and Central Sensitization in Endodontic Patients [PDF]
, 2020 Ahmed Ali Alelyani +4 more
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