Results 101 to 110 of about 34,712 (269)

Beyond symptom: Exploring the analgesic properties of vomiting in patients with migraine

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study was conducted to characterize the prevalence, temporal patterns, and the degree of vomiting‐induced migraine pain relief (VIMPR). Background Although data in the literature and anecdotal patient reports indicate the occurrence of VIMPR, its detailed characterization remains unstudied.
Antonio Munafò   +5 more
wiley   +1 more source

Effectiveness of galcanezumab versus topiramate, amitriptyline, and other select traditional oral migraine preventives with evidence of efficacy: 3‐Month results from the TRIUMPH study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To compare the 3‐month effectiveness of galcanezumab with select traditional oral migraine preventive (TOMP) medications recommended by scientific societies (TOMP efficacy subset) and with the most frequently used individual TOMP medications.
Shivang Joshi   +7 more
wiley   +1 more source

The pharmacology of gepants in migraine: A scoping review on mechanisms, clinical applications, and combination strategies

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Background Calcitonin gene‐related peptide (CGRP) is a key mediator in migraine pathophysiology, and the development of gepants, novel CGRP receptor antagonists, has expanded therapeutic options for both acute and preventive treatment. This scoping review aims to synthesize current evidence on the pharmacology, clinical applications, safety ...
Luigi Francesco Iannone   +5 more
wiley   +1 more source

Suzetrigine as a novel treatment for headache disorders: A case series

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Suzetrigine is a selective voltage‐gated sodium channel blocker that was recently approved by the US Food and Drug Administration for the treatment of acute pain. We retrospectively evaluated the efficacy and tolerability of suzetrigine for the treatment of different headache disorders in patients refractory to standard treatments in an ...
Molly Fensterwald   +15 more
wiley   +1 more source

Factors Associated With Endodontic Flare‐Ups: A Systematic Review and Meta‐Analysis

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Background Endodontic flare‐ups, characterized by severe postoperative pain and/or swelling requiring unscheduled intervention, remain a clinically significant concern in root canal therapy. Identifying the factors associated with flare‐ups is important for anticipating and managing patient outcomes.
Jun Ohshima   +8 more
wiley   +1 more source

A Unique Representation of Heat Allodynia in the Human Brain [PDF]

open access: bronze, 2002
Jürgen Lorenz   +5 more
openalex   +1 more source

Association Between the Root Canal Microbiome and Apical Lesion Size: An Observational Shotgun Metagenomic Study

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim The aim was to characterize the taxonomic and functional composition of the microbiome involved in primary endodontic infections and to evaluate their association with the periapical lesion size using shotgun metagenomic sequencing. Methodology Samples from primary root canal infections diagnosed with apical periodontitis were analysed ...
Virginia Pérez‐Carrasco   +5 more
wiley   +1 more source

Factors Associated With Postsurgical Pain in Children and Adolescents With Cognitive Dysfunction

open access: yesJournal of Clinical Nursing, EarlyView.
ABSTRACT Aim To describe the characteristics of paediatric postoperative patients with cognitive dysfunction and assess the prevalence of pain and associated factors. Desing A descriptive observational study. Methods Cross‐sectional study in children and adolescents who had undergone surgery in the previous 72 h with cognitive dysfunction impeding ...
Débora Sierra‐Núñez   +8 more
wiley   +1 more source

Ictal and interictal brain activation in episodic migraine: Neural basis for extent of allodynia

open access: gold, 2021
Nasim Maleki   +6 more
openalex   +2 more sources

Effectiveness and Tolerability of Topical Amitriptyline 10% Plus Lidocaine 2% Gel in Adults With Post‐Traumatic Trigeminal Neuropathic Pain: A Real‐World Evidence Study

open access: yesJournal of Oral Rehabilitation, EarlyView.
A compounded amitriptyline 10% plus lidocaine 2% mucoadhesive gel was associated with substantial pain improvement and favourable tolerability in adults with post‐traumatic trigeminal neuropathic pain (PTNP). These findings support targeted mucosal delivery as a promising practical local option and a potential medication‐sparing strategy, particularly ...
Ashley Lebel   +2 more
wiley   +1 more source

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