Results 131 to 140 of about 41,646 (248)

Antiallodynic and antihyperalgesic activities of zerumbone via the suppression of IL-1β, IL-6, and TNF-α in a mouse model of neuropathic pain

Journal of Pain Research, 2017
Banulata Gopalsamy, Ahmad Akira Omar Farouk, Tengku Azam Shah Tengku Mohamad, Mohd Roslan Sulaiman, Enoch Kumar Perimal Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang ...
Gopalsamy B, Farouk AAO, Tengku Mohamad TAS, Sulaiman MR, Perimal EK   +4 more
doaj  

Early Pain and Sensory Dysfunction in Drug‐Naïve Parkinson's Disease: Evidence From Quantitative Sensory Testing

European Journal of Pain, Volume 30, Issue 9, October 2026.
ABSTRACT Background Pain and sensory disturbances are common non‐motor symptoms in Parkinson's disease (PD) and can occur early in the disease course, even before starting dopaminergic treatment. However, somatosensory abnormalities in drug‐naïve PD remain insufficiently characterized, particularly in the absence of dopaminergic medication effects ...
Maria Skallerup Andersen, Lorenz Martin Oppel, Boris Modrau, Kimmo Jensen, Gertrud Dam‐Dalgeir, Parisa Gazerani   +5 more
wiley   +1 more source

Targeting the endogenous cannabinoid system to treat chronic neuropathic pain

Frontiers in Pharmacology, 2014
Benjamin K Lau, Christopher W Vaughan
doaj   +1 more source

The TRPM2–PARP‐1 Axis Involvement in Bisphenol A and Nonylphenol‐Induced Ferroptosis in Trigeminal Ganglion Cells

Journal of Applied Toxicology, Volume 46, Issue 10, Page 3660-3674, October 2026.
ABSTRACT Environmental contaminants like bisphenol A (BPA) and nonylphenol (NP) are recognized neurotoxicants; however, the molecular mechanisms underlying their impact on sensory ganglia, specifically the trigeminal ganglion (TG), remain critically underexplored.
Betül Yazğan, Musa Tatar, Yener Yazğan, Kıymet Kübra Tüfekci   +3 more
wiley   +1 more source

The Role of the Antidepressants in Managing Chemotherapy‐Induced Neuropathic Pain: A Systematic Review

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
From symptom relief to multimodal care: duloxetine and amitriptyline may reduce established CIPN‐related pain and provide a therapeutic foundation for future combination strategies. ABSTRACT Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and debilitating complication of cancer treatment, characterized by neuropathic pain, sensory ...
Rosamaria Caminiti, Valeria Mazza, Saverio Nucera, Francesca Oppedisano, Lucia Carmela Passacatini, Jessica Maiuolo, Valentina Malafoglia, Alessandro Giorgio, Andrea Soluri, Claudia Pileggi, Carlo Tomino, Vincenzo Mollace, Sara Ilari, Carolina Muscoli   +13 more
wiley   +1 more source

Cannabinoid CB1 allosteric ligands suppress inflammatory pain in male mice without tolerance, motor impairment, memory deficits or respiratory depression

British Journal of Pharmacology, Volume 183, Issue 20, Page 6132-6153, October 2026.
Abstract Background and Purpose Positive allosteric modulators (PAMs) engage sites distinct from the orthosteric CB1 cannabinoid receptor binding site. GAT211, a racemic ligand, contains GAT228 (R) and GAT229 (S) enantiomers. Whether enantiomer‐mediated differences in allosteric activation or positive allosteric modulation translate into differences in
Ifeoluwa D. Solomon, Sumanta Garai, Ganesh A. Thakur, Andrea G. Hohmann   +3 more
wiley   +1 more source

Sex-related analgesic responses to photobiomodulation therapy in rats with neuropathic pain. [PDF]

Lasers Med Sci
Marques NF, Bonifacio RP, Jesus JM, Santos MER, Grande MC, Quimuanga HC, Goncalves MIC, Silva DPFB, Chacur M.   +8 more
europepmc   +1 more source

A TRIP‐nano killer silencing the pain pacemakers

The Journal of Physiology, EarlyView.
Elisabetta Cerbai
wiley   +1 more source

Neuroimmune alterations and nociceptive behavior in oral carcinogenesis in rats

European Journal of Oral Sciences, Volume 134, Issue 5, October 2026.
Abstract Oral cancer pain is a frequent and debilitating symptom associated with tumor progression. Although neuronal mechanisms have been extensively studied, the role of immune and glial cells in the trigeminal nociceptive pathway remains poorly understood.
Joana Maria dos Santos Alves, Luiza Clertiani Vieira Alves, Vitória Tavares Bessa, Anamaria Falcão Pereira, Roberto César Pereira Lima Júnior, Mariana Lima Vale, Karuza Maria Alves Pereira, Delane Viana Gondim   +7 more
wiley   +1 more source

The Ethanol-Insoluble Low-Molecular-Weight Fraction LEP-4 Derived From <i>Lentinula edodes</i> Mycelia Extract Attenuates Oxaliplatin-Evoked Allodynia in Mice. [PDF]

Adv Pharmacol Pharm Sci
Tsubaki M, Matsuo T, Komori R, Takeda T, Nagai N, Morikawa T, Nishida S.   +6 more
europepmc   +1 more source