Results 131 to 140 of about 31,723 (232)

Incidence and assessment of mechanical allodynia and its association with dental anxiety in endodontic pain: A clinical study. [PDF]

J Conserv Dent Endod
Vishal M, Padala S, Soujanya E, Kaushik M.   +3 more
europepmc   +1 more source

An Olfactory Piriform Cortex‐Lateral Hypothalamus Neural Circuit Contributes to Linalool‐Induced Analgesia

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
Linalool odor exposure activates a glutamatergic projection from the piriform cortex to the lateral hypothalamus (PiriGlu‐LH), mediating descending inhibitory pain pathways. This demonstrates a novel neural mechanism for olfactory‐induced pain modulation and suggests potential therapeutic implications for pain management.
Yunhe Zhu, Jingping Sun, Shan Wang, Qidong Zhang, Jian Mao, Guobi Chai, Qingzhao Shi, Wu Fan, Jianping Xie   +8 more
wiley   +1 more source

Peripheral Sympathetic Sprouting Drives Neuropathic Pain via Spinal Microglial P2Y12 Activation in a Rat Spinal Nerve Ligation Model. [PDF]

J Pain Res
Yu T, Huang H, Li Z, Yan H.
europepmc   +1 more source

Mechanisms Underlying Pain Avoidance in Complex Regional Pain Syndrome

European Journal of Pain, Volume 30, Issue 7, August 2026.
ABSTRACT Background Maladaptive pain avoidance plays a critical role in chronic pain development and maintenance. Pain avoidance reinforced instrumentally through action‐outcome contingencies remains poorly understood, specifically in complex regional pain syndrome (CRPS), a nociplastic condition.
Raghavan Gopalakrishnan, Nitesh Singh Malan, Claire Sonneborn, Olivia Hogue, Pavan Tankha, Sylvain Baillet, Mathieu Roy   +6 more
wiley   +1 more source

Botulinum toxin type E alleviates trigeminal neuropathic pain via modulation of the HIF-1α-NLRP3 pathway. [PDF]

Front Toxicol
Son J, Kim Y, Ju J, Kim J, Nam J, Cha Y, Ahn D.   +6 more
europepmc   +1 more source

Safety Profile of Sclerosing Agents in the Management of Low‐Flow Vascular Malformations of the Head and Neck—A Systematic Review

Head &Neck, Volume 48, Issue 8, Page 2290-2305, August 2026.
ABSTRACT Background Low‐flow vascular malformations (LFVMs) of the head and neck, including venous and lymphatic malformations, represent a heterogeneous group of congenital anomalies frequently requiring intervention due to functional and esthetic impairment.
Riccardo Nocini, Carlotta Muneretto, Athena E. Arsie, Valerio Arietti, Benedetta Lorenzon, Alessandra Cinotti, Giacomo Colletti   +6 more
wiley   +1 more source

DN4 Is Not a Screening Tool for Small Fiber Neuropathy: An Expected Result. [PDF]

Eur J Neurol
Lefaucheur JP.
europepmc   +1 more source

Ultrasound‐Guided Liposomal vs. Conventional Bupivacaine Erector Spinae Plane Block Plus Gabapentin for Postherpetic Neuralgia

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 8, August 2026.
ABSTRACT This study aimed to compare efficacy and safety of ultrasound‐guided erector spinae plane block (ESPB) using liposomal (LB) versus conventional bupivacaine (CB), each plus standardized gabapentin, in patients with postherpetic neuralgia (PHN). A total of 116 PHN patients were randomized to ESPB‐LB or ESPB‐CB; both groups received standardized ...
Xia‐Jing Xu, Li‐Juan Liu, Fa‐Ming Xu, Xiang‐Yu Fang   +3 more
wiley   +1 more source

Deferoxamine Improves Radiation-Induced Peripheral Neuropathy. [PDF]

J Cell Mol Med
Lavin CV, Fazilat AZ, Kendig CB, Shibale P, Huang KX, Nemani S, Parker JB, Valencia C, Ailury NAR, Griffin M, Momeni A, Longaker MT, Wan DC.   +12 more
europepmc   +1 more source

Pharmacological Inhibition of Cav2.2 Channels by Recombinant Phα1β Toxin (CTK01512‐2)

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
The recombinant Phα1β toxin (CTK01512‐2) partially and reversibly inhibits Cav2.2 calcium channels in HEK‐293 cells. CTK01512‐2 displays dose‐dependent inhibition of N‐type calcium currents, with an IC50 of 3.94 nM. In vivo, CTK01512‐2 effectively reduces mechanical allodynia in a neuropathic pain model, confirming its antinociceptive activity ...
Natália Virtude Carobin, Thamyris Reis Moraes, Luana Assis Ferreira, Christopher Kushmerick, Marcus Vinícius Gomez, Célio José Castro Junior   +5 more
wiley   +1 more source