CO- TRANSPLANTATION OF BONE MARROW STROMAL CELLS WITH SCHWANN CELLS EVOKES MECHANICAL ALLODYNIA IN THE CONTUSION MODEL OF SPINAL CORD INJURY IN RATS [PDF]
Objective: Several studies have shown that, although transplantation of neural stem cells into the contusion model of spinal cord injury (SCI) promotes locomotor function and improves functional recovery, it induces a painful response, Allodynia ...
بختیاری, مهرداد+5 more
core
Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury. [PDF]
The goal of stem cell therapy for spinal cord injury (SCI) is to restore motor function without exacerbating pain. Induced pluripotent stem cells (iPSC) may be administered by autologous transplantation, avoiding immunologic challenges.
Brifault, Coralie+11 more
core
The development of cutaneous allodynia during a migraine attack Clinical evidence for the sequential recruitment of spinal and supraspinal nociceptive neurons in migraine [PDF]
Rami Burstein
openalex +1 more source
ABSTRACT Background Pressure pain thresholds (PPT) are a component of Quantitative Sensory Testing and are used to assess mechanical pain sensitivity. Joint‐specific PPT measurements are relevant because many joint disorders involve altered pain processing at and around joints. This study aims to establish such reference values that might contribute to
Fabian Tomschi+3 more
wiley +1 more source
Allodynia and Pinprick Hypesthesia in Acute Herpes Zoster, and the Development of Postherpetic Neuralgia [PDF]
Maija Haanpää+2 more
openalex +1 more source
ABSTRACT Introduction Chronic pain after total knee arthroplasty (TKA) affects approx. 15%–20% of patients undergoing surgery. It is largely unexplained why some patients develop chronic pain after TKA, but several factors, e.g., central pain mechanisms and psychosocial factors, have been suggested.
Jesper Bie Larsen+5 more
wiley +1 more source
Antagonism of the Melanocortin System Reduces Cold and Mechanical Allodynia in Mononeuropathic Rats [PDF]
Dorien H. Vrinten+3 more
openalex +1 more source
ABSTRACT Background Glutamate, the primary neurotransmitter released by nociceptors, is predominantly synthesised by the enzyme Glutaminase 1 (GLS1). The involvement of GLS1 in pain pathways is well supported, as Gls1 heterozygous mice exhibit altered nociception and GLS1 levels increase in the dorsal root ganglia (DRG) under chronic peripheral ...
Anabel Martínez‐Padilla+4 more
wiley +1 more source
Local inhibitory effects of dynorphin A-(1–17) on capsaicin-induced thermal allodynia in rhesus monkeys [PDF]
Mei‐Chuan Ko+4 more
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ABSTRACT Osteoarthritis (OA) is a highly prevalent chronic joint disorder affecting ~600 million individuals worldwide and is characterized by complex pain mechanisms that significantly impair patient quality of life. Challenges exist in accurately assessing and measuring pain in OA due to variations in pain perception among individuals and the ...
Shujaa T. Khan+10 more
wiley +1 more source