Results 131 to 140 of about 52,858 (307)

CO- TRANSPLANTATION OF BONE MARROW STROMAL CELLS WITH SCHWANN CELLS EVOKES MECHANICAL ALLODYNIA IN THE CONTUSION MODEL OF SPINAL CORD INJURY IN RATS [PDF]

open access: yes
Objective: Several studies have shown that, although transplantation of neural stem cells into the contusion model of spinal cord injury (SCI) promotes locomotor function and improves functional recovery, it induces a painful response, Allodynia ...
بختیاری, مهرداد   +5 more
core  

Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury. [PDF]

open access: yes, 2019
The goal of stem cell therapy for spinal cord injury (SCI) is to restore motor function without exacerbating pain. Induced pluripotent stem cells (iPSC) may be administered by autologous transplantation, avoiding immunologic challenges.
Brifault, Coralie   +11 more
core  

Reference Values of Joint‐Specific Pressure Pain Thresholds in Healthy Male Individuals: A Retrospective Study

open access: yesEuropean Journal of Pain, Volume 29, Issue 6, July 2025.
ABSTRACT Background Pressure pain thresholds (PPT) are a component of Quantitative Sensory Testing and are used to assess mechanical pain sensitivity. Joint‐specific PPT measurements are relevant because many joint disorders involve altered pain processing at and around joints. This study aims to establish such reference values that might contribute to
Fabian Tomschi   +3 more
wiley   +1 more source

Pain Mechanisms and Psychosocial Variables in Patients With Chronic Pain After Total Knee Arthroplasty: Secondary Analysis From a Randomised Controlled Trial

open access: yesEuropean Journal of Pain, Volume 29, Issue 6, July 2025.
ABSTRACT Introduction Chronic pain after total knee arthroplasty (TKA) affects approx. 15%–20% of patients undergoing surgery. It is largely unexplained why some patients develop chronic pain after TKA, but several factors, e.g., central pain mechanisms and psychosocial factors, have been suggested.
Jesper Bie Larsen   +5 more
wiley   +1 more source

Antagonism of the Melanocortin System Reduces Cold and Mechanical Allodynia in Mononeuropathic Rats [PDF]

open access: hybrid, 2000
Dorien H. Vrinten   +3 more
openalex   +1 more source

Loss of Glutaminase 1 in Small Sensory Neurons Prevents Nerve Injury Induced Mechanical Allodynia: Insights From Conditional Knockout Mice

open access: yesEuropean Journal of Pain, Volume 29, Issue 6, July 2025.
ABSTRACT Background Glutamate, the primary neurotransmitter released by nociceptors, is predominantly synthesised by the enzyme Glutaminase 1 (GLS1). The involvement of GLS1 in pain pathways is well supported, as Gls1 heterozygous mice exhibit altered nociception and GLS1 levels increase in the dorsal root ganglia (DRG) under chronic peripheral ...
Anabel Martínez‐Padilla   +4 more
wiley   +1 more source

Local inhibitory effects of dynorphin A-(1–17) on capsaicin-induced thermal allodynia in rhesus monkeys [PDF]

open access: green, 2000
Mei‐Chuan Ko   +4 more
openalex   +1 more source

Pain Assessment in Osteoarthritis: Present Practices and Future Prospects Including the Use of Biomarkers and Wearable Technologies, and AI‐Driven Personalized Medicine

open access: yesJournal of Orthopaedic Research, Volume 43, Issue 7, Page 1217-1229, July 2025.
ABSTRACT Osteoarthritis (OA) is a highly prevalent chronic joint disorder affecting ~600 million individuals worldwide and is characterized by complex pain mechanisms that significantly impair patient quality of life. Challenges exist in accurately assessing and measuring pain in OA due to variations in pain perception among individuals and the ...
Shujaa T. Khan   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy