Galectin-3. One molecule for an alphabet of diseases, from A to Z [PDF]
, 2018 Galectin-3 (Gal-3) regulates basic cellular functions such as cell–cell and cell–matrix interactions, growth, proliferation, differentiation, and inflammation.
Bellotti, Carlo +8 more
core +2 more sources
Postherpetic Neuralgia: Irritable Nociceptors and Deafferentation
Neurobiology of Disease, 1998 Postherpetic neuralgia (PHN) is a common and often devastatingly painful condition. It is also one of the most extensively investigated of the neuropathic pains. Patients with PHN have been studied using quantitative testing of primary afferent function,
Howard L. Fields +2 more
doaj
Metabotropic glutamate receptor 2/3 (mGluR2/3) activation suppresses TRPV1 sensitization in mouse, but not human sensory neurons [PDF]
, 2018 The use of human tissue to validate putative analgesic targets identified in rodents is a promising strategy for improving the historically poor translational record of preclinical pain research.
Baranger, David A.A. +5 more
core +2 more sources
Concentration–Effect Relationship of Intravenous Lidocaine on the Allodynia of Complex Regional Pain Syndrome Types I and II [PDF]
, 2000 Mark S. Wallace +4 more
openalex +1 more source
Molecular Pain, 2016 The primary complaint of burn victims is an intense, often devastating spontaneous pain, with persistence of mechanical and thermal allodynia. The transient receptor potential channels, TRPV1 and TRPA1, are expressed by a subset of nociceptive sensory ...
D. Green +6 more
semanticscholar +1 more source
Allodynia in cluster headache: a review
Headache Medicine, 2011 Allodynia is defined as the experience of pain due to nonpainful stimuli, and occurs in several clinical contexts, including primary headaches. Cluster headache is a primary cephalalgia which is more common in males, characterized by excruciating pain, and autonomic trigeminal dysfunction.
Marcelo Moraes Valença +2 more
openaire +2 more sources
The development of cutaneous allodynia during a migraine attack Clinical evidence for the sequential recruitment of spinal and supraspinal nociceptive neurons in migraine [PDF]
, 2000 Rami Burstein
openalex +1 more source
Serum Biomarkers and Their Clinical Correlates in Traumatic Trigeminal Neuropathy: A Pilot Study
Oral Diseases, EarlyView.ABSTRACT Objectives This study aims to investigate the serum biomarker levels in patients with painful post‐traumatic trigeminal neuropathy (PPTTN) and explore the associations between these biomarkers and the clinical and psychological characteristics of the patients. Materials and Methods A total of 32 patients with PPTTN were included.
Hye‐Kyoung Kim +2 more
wiley +1 more source
Veterinary Dermatology, EarlyView.Background: Gabapentin reportedly decreases central sensitisation, a disorder associated with chronic pruritus in humans, although this is not well documented in cats. Its combined use with the standard antipruritic therapy for feline atopic skin syndrome (FASS) is not yet described.
Jeanne Morency +10 more
wiley +1 more source
Perturbations in neuroinflammatory pathways are associated with paclitaxel-induced peripheral neuropathy in breast cancer survivors. [PDF]
, 2019 Paclitaxel is a common chemotherapy drug associated with the development of chronic paclitaxel-induced peripheral neuropathy (PIPN). PIPN is associated with neuroinflammatory mechanisms in pre-clinical studies.
Abrams, Gary +9 more
core