Stable dose cannabinoid medicine (Sativex®, THC+CBD) can provide sustained efficacy in the treatment of refractory painful diabetic neuropathy or other peripheral neuropathic pain associated with allodynia [poster] [PDF]
No abstract ...
Hoggart, B. +3 more
core
ABSTRACT This study aimed to compare efficacy and safety of ultrasound‐guided erector spinae plane block (ESPB) using liposomal (LB) versus conventional bupivacaine (CB), each plus standardized gabapentin, in patients with postherpetic neuralgia (PHN). A total of 116 PHN patients were randomized to ESPB‐LB or ESPB‐CB; both groups received standardized ...
Xia‐Jing Xu +3 more
wiley +1 more source
The interaction of intrathecal neostigmine and N-cyclohexyladenosine on anti-allodynic effects in rats with a nerve ligation injury [PDF]
BackgroundNerve ligation injury in rats produces a pain syndrome that includes mechanical allodynia. Intrathecal administration of cholinesterase inhibitors or adenosine receptor agonists have anti-allodynic effects in this model.
Dae Kee Choi +2 more
doaj +1 more source
Abstract Background Ultrasonography is useful for evaluating cutaneous nerve lesions. Objective To investigate the clinical utility of ultrasonography in accurately localizing nerve abnormalities in distal superficial radial neuropathy, based on clinical symptoms and electrodiagnostic test results. Design Retrospective descriptive study.
Hong Bum Park +3 more
wiley +1 more source
The alternatively spliced fibronectin CS1 isoform regulates IL-17A levels and mechanical allodynia after peripheral nerve injury. [PDF]
BackgroundMechanical pain hypersensitivity associated with physical trauma to peripheral nerve depends on T-helper (Th) cells expressing the algesic cytokine, interleukin (IL)-17A.
Angert, Mila +9 more
core +3 more sources
Nanoemulsions for Skin Delivery of Essential Oils: A Systematic Review
ABSTRACT Essential oils (EOs) are recognized for their multiple health benefits. However, their high volatility, low stability, and limited water solubility limit their effective application. This systematic review aims to assess the use of nanoemulsions as delivery systems for the topical administration of EOs, highlighting their efficacy, safety, and
Thais Leticia Moreira da Silva +3 more
wiley +1 more source
The study aimed to evaluate the effects of monoclonal antibodies (mAbs) acting on the calcitonin gene-related peptide (CGRP) or its receptor (anti-CGRP/R mAbs) on migraine comorbidities of depression, anxiety, and fatigue in patients resistant to ...
Alessandra Della Vecchia +7 more
doaj +1 more source
Development and initial validation of a sensory threshold examination protocol (STEP) for phenotyping canine pain syndromes [PDF]
Objective To study feasibility and test-retest repeatability of a sensory threshold examination protocol (STEP) and report quantitative sensory threshold distributions in healthy dogs.
Abeyesinghe, S M +5 more
core +2 more sources
This cross‐sectional study enrolled Thai patients with spondyloarthritis to assess the prevalence and its impact. Fibromyalgia was present in 5.5% and significantly impaired health‐related quality of life and symptom perception. Low disease activity, good sleep quality, and FS < 3 were independently associated with achieving PASS.
Sittikorn Srivorrapattararkul +1 more
wiley +1 more source
RNA Sequencing Dataset of Drosophila Nociceptor Translatomic Response to Injury
To prepare to address the mechanisms of injury-induced nociceptor sensitization, we sequenced the translatome of the nociceptors of injured Drosophila larvae and those of uninjured larvae.
Christine M. Hale +6 more
doaj +1 more source

