Results 61 to 70 of about 34,712 (269)

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

Autism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin, Arthur N. Westover, Amy S. F. Lutz, Manish K. Jha   +3 more
wiley   +1 more source

Neurofilament light chain as in vitro and clinical biomarker of vincristine‐induced peripheral neuropathy

British Journal of Clinical Pharmacology, EarlyView.
Aims Vincristine‐induced peripheral neuropathy (VIPN) is a common side effect in children and adolescents treated with vincristine. Assessing VIPN, especially in young children, is challenging due to a lack of sensitive tools. This limits our understanding of the nature and risk factors of VIPN. This study aimed to investigate neurofilament light chain
Peter Erik Lotko Pontoppidan, Christian Bach Vase, Christina Mortensen, Liv Andres‐Jensen, Dorte Aalund Olsen, Jonna Skov Madsen, Kjeld Schmiegelow, Rene Mathiasen, Tore Bjerregaard Stage   +8 more
wiley   +1 more source

The interaction of intrathecal neostigmine and N-cyclohexyladenosine on anti-allodynic effects in rats with a nerve ligation injury [PDF]

Korean Journal of Anesthesiology, 2010
BackgroundNerve ligation injury in rats produces a pain syndrome that includes mechanical allodynia. Intrathecal administration of cholinesterase inhibitors or adenosine receptor agonists have anti-allodynic effects in this model.
Dae Kee Choi, Seong Soo Choi, Jai Hyun Hwang   +2 more
doaj   +1 more source

Notch1 Signaling Contributes to Mechanical Allodynia Associated with Cyclophosphamide‐Induced Cystitis by Promoting Microglia Activation and Neuroinflammation [PDF]

, 2021
Jialiang Chen, Honglu Ding, Bolong Liu, Xiangfu Zhou, Xin Zhou, Zhijun Lin, Fei Yang, Hailun Zhan, Hengjun Xiao   +8 more
openalex   +1 more source

Safety Profile of Sclerosing Agents in the Management of Low‐Flow Vascular Malformations of the Head and Neck—A Systematic Review

Head &Neck, EarlyView.
ABSTRACT Background Low‐flow vascular malformations (LFVMs) of the head and neck, including venous and lymphatic malformations, represent a heterogeneous group of congenital anomalies frequently requiring intervention due to functional and esthetic impairment.
Riccardo Nocini, Carlotta Muneretto, Athena E. Arsie, Valerio Arietti, Benedetta Lorenzon, Alessandra Cinotti, Giacomo Colletti   +6 more
wiley   +1 more source

Clinical observation of the effect of prophylaxis on allodynia in patients with migraine

Journal of Pain Research, 2018
Na Zhang,1 Chun-Fu Chen2 1Department of Emergency Medicine, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, China; 2Department of Neurology, Shandong Provincial Hospital, Shandong University, Jinan 250021, China Objective: The
Zhang N, Chen CF
doaj  

Efficacy and safety of laparoscopic nerve decompression for neuropathic sciatic pain due to endometriosis: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Endometriosis is associated with neuropathic pain in approximately 40% of cases. Involvement of the sciatic nerve or sacral plexus represents one of the most frequently reported neuropathic pain presentations in endometriosis, for which no specific management guidelines currently exist.
Camille Racca, Julia Franken, Marion Cahen, Aurelly Cicchelero, Murielle Mormont, Raphaël Cinotti   +5 more
wiley   +1 more source

Beyond Pain Relief: Unveiling the Multifaceted Impact of Anti-CGRP/R mAbs on Comorbid Symptoms in Resistant Migraine Patients

Biomedicines
The study aimed to evaluate the effects of monoclonal antibodies (mAbs) acting on the calcitonin gene-related peptide (CGRP) or its receptor (anti-CGRP/R mAbs) on migraine comorbidities of depression, anxiety, and fatigue in patients resistant to ...
Alessandra Della Vecchia, Ciro De Luca, Lucrezia Becattini, Letizia Curto, Elena Ferrari, Gabriele Siciliano, Sara Gori, Filippo Baldacci   +7 more
doaj   +1 more source

Skin keratinocyte-derived SIRT1 and BDNF modulate mechanical allodynia in mouse models of diabetic neuropathy [PDF]

, 2023
Jennifer OʼBrien, Peter Niehaus, Koping Chang, Juliana Remark, Joy Barrett, Abhishikta Dasgupta, Morayo Adenegan, Mohammad Salimian, Yanni Kevas, Krish Chandrasekeran, Tibor Kristián, Rajeshwari Chellappan, Samuel J. Rubin, Ashley Kiemen, Ping Lu, James W. Russell, Cheng-Ying Ho   +16 more
openalex   +1 more source

The TRPM2–PARP‐1 Axis Involvement in Bisphenol A and Nonylphenol‐Induced Ferroptosis in Trigeminal Ganglion Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental contaminants like bisphenol A (BPA) and nonylphenol (NP) are recognized neurotoxicants; however, the molecular mechanisms underlying their impact on sensory ganglia, specifically the trigeminal ganglion (TG), remain critically underexplored.
Betül Yazğan, Musa Tatar, Yener Yazğan, Kıymet Kübra Tüfekci   +3 more
wiley   +1 more source