Results 71 to 80 of about 34,712 (269)

RNA Sequencing Dataset of Drosophila Nociceptor Translatomic Response to Injury

Data
To prepare to address the mechanisms of injury-induced nociceptor sensitization, we sequenced the translatome of the nociceptors of injured Drosophila larvae and those of uninjured larvae.
Christine M. Hale, Kyle J. Beauchemin, Courtney L. Brann, Julie K. Moulton, Ramaz Geguchadze, Benjamin J. Harrison, Geoffrey K. Ganter   +6 more
doaj   +1 more source

Protective Effects of Imeglimin Against Oxaliplatin‐Induced Peripheral Neurotoxicity: Evidence From In Vitro and In Vivo Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Oxaliplatin is a platinum‐based anticancer agent widely used for gastrointestinal malignancies; however, it is known to cause dose‐dependent peripheral neuropathy (OIPN), a characteristic adverse effect. OIPN results in a reduced quality of life and often necessitates dose reduction or discontinuation of oxaliplatin; however, effective ...
Yusuke Koura, Kano Kinjo, Keisuke Mine, Yusuke Mori, Mami Ueda, Risa Kaneko, Yuna Kamiya, Taiga Sonoda, Haruka Mimata, Shunsuke Fujita, Takehiro Kawashiri, Daisuke Kobayashi   +11 more
wiley   +1 more source

Ultrasound‐Guided Liposomal vs. Conventional Bupivacaine Erector Spinae Plane Block Plus Gabapentin for Postherpetic Neuralgia

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to compare efficacy and safety of ultrasound‐guided erector spinae plane block (ESPB) using liposomal (LB) versus conventional bupivacaine (CB), each plus standardized gabapentin, in patients with postherpetic neuralgia (PHN). A total of 116 PHN patients were randomized to ESPB‐LB or ESPB‐CB; both groups received standardized ...
Xia‐Jing Xu, Li‐Juan Liu, Fa‐Ming Xu, Xiang‐Yu Fang   +3 more
wiley   +1 more source

Antiallodynic Effects of Bee Venom in an Animal Model of Complex Regional Pain Syndrome Type 1 (CRPS-I)

Toxins, 2017
Neuropathic pain in a chronic post-ischaemic pain (CPIP) model mimics the symptoms of complex regional pain syndrome type I (CRPS I). The administration of bee venom (BV) has been utilized in Eastern medicine to treat chronic inflammatory diseases ...
Sung Hyun Lee, Jae Min Lee, Yun Hong Kim, Jung Hyun Choi, Seung Hwan Jeon, Dong Kyu Kim, Hyeon Do Jeong, You Jung Lee, Hue Jung Park   +8 more
doaj   +1 more source

Oromucosal Administration of a Cannabidiol-Enriched Cannabis sp. Extract for 2 Weeks Moderately Reduces Cold Hyperalgesia in Rats With Neuropathic Pain. [PDF]

Eur J Pain
ABSTRACT Background Chronic neuropathic pain (CNP) involves complex interactions between resident and peripheral immune cells, as well as modulation of the endocannabinoid system. Cannabis‐based products have emerged as promising therapeutic options, but their effects on immune cells remain unclear.
Campos RMP, Conde L, Aguiar A, Sampaio L, de Melo Reis RA, Pimentel-Coelho PM.   +5 more
europepmc   +2 more sources

Collagen‐membrane‐covered matrix‐associated chondrocyte implantation improves safety over periosteum‐covered MACI for large knee cartilage defects: A real‐world data analysis in the registry study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This registry study aimed to evaluate the safety and effectiveness of collagen membrane‐covered matrix‐associated autologous chondrocyte implantation (cMACI) versus periosteum‐covered MACI (pMACI) for large knee cartilage defects (Outerbridge III–IV, ≥4 cm²) in the femorotibial and/or patellofemoral joints with a minimum 2‐year follow ...
Yuji Uchio, Ryosuke Kuroda, Yasuo Niki, Katsura Sugawara, Yasuyuki Ishibash   +4 more
wiley   +1 more source

The analgesic effect of intravenous methylprednisolone on acute neuropathic pain with allodynia due to central cord syndrome: a retrospective study

Journal of Pain Research, 2018
Liandong Li,1 Yawei Han,2 Tengshuai Li,1 Jiaming Zhou,1 Chao Sun,3,4 Yuan Xue1 1Department of Orthopaedics Surgery, Tianjin Medical University General Hospital, Tianjin, China; 2Department of Histology and Embryology, School of Basic Medical Sciences ...
Li L, Han Y, Li T, Zhou J, Sun C, Xue Y
doaj  

Epigenetic Regulation of Immune Dysfunction in Chronic Prostatitis/Chronic Pelvic Pain Syndrome

The Prostate, EarlyView.
ABSTRACT Background Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent and debilitating condition with unclear etiology. Increasing evidence implicates immune dysregulation, yet the molecular mechanisms underlying impaired immune regulation remain poorly defined. This study investigated the role of altered immune responses within
Praveen Thumbikat, Goutham Pattabiraman, Farzaneh Sharifzad, Yongyong Yang, Zhiqiang Liu, Catherine V. Osborn, Stephen F. Murphy, Qi Cao, Anthony J. Schaeffer   +8 more
wiley   +1 more source

Impact of fibromyalgia on patient acceptable symptom state in Thai patients with spondyloarthritis: A cross‐sectional study

Rheumatology &Autoimmunity, EarlyView.
This cross‐sectional study enrolled Thai patients with spondyloarthritis to assess the prevalence and its impact. Fibromyalgia was present in 5.5% and significantly impaired health‐related quality of life and symptom perception. Low disease activity, good sleep quality, and FS < 3 were independently associated with achieving PASS.
Sittikorn Srivorrapattararkul, Praveena Chiowchanwisawakit   +1 more
wiley   +1 more source

Complex regional pain syndrome: medical and legal ramifications of clinical variability and experience and perspective of a practicing clinician

Journal of Pain Research, 2016
RP Lazaro Department of Neurology, Albany Medical College, Albany, NY, USA Objective: The aim of this study was to demonstrate the ramifications of clinical variability of complex regional pain syndrome (CRPS) and how they can affect the various aspects ...
Lazaro RP
doaj