Results 81 to 90 of about 200 (121)
Inhibition of Lytic Reactivation of Kaposi'S Sarcoma-Associated Herpesvirus by Alloferon
Antiviral Therapy, 2011 Background Alloferon, an immunomodulatory peptide, has antiviral capability against herpesvirus. In this research, we aimed to investigate the effect of alloferon on the regulation of the life cycle of Kaposi's sarcoma-associated herpesvirus (KSHV), and ...
Sung-Joon Kim +2 more
exaly +2 more sources
Some of the next articles are maybe not open access.
THE EFFECTIVENESS OF ALLOFERON IN THE COMPLEX THERAPY OF CHRONIC RECURRENT PAPILLOMAVIRUS CYSTITIS
Themed collection of papers from Foreign intemational scientific conference «Joint innovation - joint development». Medical sciences . Part 2. Ьу НNRI «National development» in cooperation with PS of UA. June 2023, 2023Introduction: Chronic recurrent cystitis (CRC) for women is one of the most pressing and unresolved problems of modern urology. Purpose of the research: To study the effectiveness of Alloferon (Allokin-alpha) in the complex therapy of chronic reactive papillomavirus cystitis. Materials and methods: 46 patients with CRC PV-etiology were examined, which,
Andrey Ivanovich Singe +3 more
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New Alloferon Analogues: Synthesis and Antiviral Properties
Chemical Biology & Drug Design, 2012We have extended our study on structure/activity relationship studies of insect peptide alloferon (H‐His‐Gly‐Val‐Ser‐Gly‐His‐Gly‐Gln‐His‐Gly‐Val‐His‐Gly‐OH) by evaluating the antiviral effects of new alloferon analogues. We synthesized 18 alloferon analogues: 12 peptides with sequences shortened from N‐ or C‐terminus and 6 N‐terminally modified ...
Kuczer, M. +2 more
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Alloferon improves the growth performance and developmental time of mealworms (Tenebrio molitor)
Journal of Emerging Investigators, 2023Mealworms (Tenebrio molitor) are important food sources for reptiles, birds, and other organisms, as well as for humans. Due to their outstanding nutritional value, mealworms are in high demand as an alternative food source and are the subject of widespread curiosity.
Jimin Shon, David Shon, Woo Jin Kim
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The Journal of Immunology, 2022
Abstract Pancreatic cancer is one of the most malignant solid tumors with a high mortality rate. Although there have been many trials for effective therapies using chemotherapeutic drugs, such as gemcitabine, pancreatic cancer still shows significantly higher mortality than other types of cancer.
HyeJung Jo +4 more
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Abstract Pancreatic cancer is one of the most malignant solid tumors with a high mortality rate. Although there have been many trials for effective therapies using chemotherapeutic drugs, such as gemcitabine, pancreatic cancer still shows significantly higher mortality than other types of cancer.
HyeJung Jo +4 more
openaire +1 more source
Activation of NF-κB by alloferon through down-regulation of antioxidant proteins and IκBα
Molecular and Cellular Biochemistry, 2008Alloferon is a 13-amino acid peptide isolated from the bacteria-challenged larvae of the blow fly Calliphora vicina. The pharmaceutical value of the peptide has been well demonstrated by its capacity to stimulate NK cytotoxic activity and interferon (IFN) synthesis in animal and human models, as well as to enhance antiviral and antitumor activities in ...
Cheolju Lee, Yeon Gyu Yu, Myeong-Hee Yu
exaly +4 more sources
Biochemical blood parameters of patients with aleutian mink disease under the influence of alloferon
International Journal of Veterinary Medicine, 2023Fur farming in Russia can be considered one of the most profitable industries. However, outbreaks of infectious diseases in animal farms, in the difficult conditions of the global financial crisis, cause irreparable economic damage, which negatively affects the prospects for the development of the industry.
A. A. Sukhinin, M. M. Gumberidze
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Novel biological effects of alloferon and its selected analogues: Structure–activity study
Regulatory Peptides, 2013The subject of this paper is a search for new biological properties of alloferon (H-His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly-OH) and a series of its analogues. The studies on structure/activity relationship in alloferon, the synthesis of a series of 28 analogues were performed.
Mariola, Kuczer +2 more
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Russian Journal of Bioorganic Chemistry, 2006
Two variants of the synthesis of tridecapeptide alloferon, the active principle of antiviral preparation allokine-alpha, were developed on the basis of fragment condensation in solution or on the Merrifield resin. The solid phase variant of the synthesis was shown to be more technological; it allows the preparation of the product at a higher total ...
Alexander Molokoedov +2 more
exaly +2 more sources
Two variants of the synthesis of tridecapeptide alloferon, the active principle of antiviral preparation allokine-alpha, were developed on the basis of fragment condensation in solution or on the Merrifield resin. The solid phase variant of the synthesis was shown to be more technological; it allows the preparation of the product at a higher total ...
Alexander Molokoedov +2 more
exaly +2 more sources
Novel analogs of alloferon: Synthesis, conformational studies, pro-apoptotic and antiviral activity
Bioorganic Chemistry, 2016In this study, we report the structure-activity relationships of novel derivatives of the insect peptide alloferon (H-His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly-OH). The peptide structure was modified by exchanging His at position 9 or 12 for natural or non-natural amino acids.
Kuczer, Mariola +5 more
openaire +2 more sources