Results 91 to 100 of about 200 (121)
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Studies of insect peptides alloferon, Any‐GS and their analogues. Synthesis and antiherpes activity

Journal of Peptide Science, 2010
AbstractThe subject of these studies was synthesis and determination of biological properties of a series of insect peptides, such as alloferon, Any‐GS and their analogues. The synthesis of 14 peptides was performed by the solid‐phase method. Biological effect of these peptides was evaluated by the antiviral test against Human Herpes Virus type 1 (HHV ...
Kuczer, Mariola   +5 more
openaire   +2 more sources

Mononuclear copper(II) complexes of alloferons 1 and 2: A combined potentiometric and spectroscopic studies

Journal of Inorganic Biochemistry, 2009
Mononuclear copper(II) complexes of the alloferon 1 His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly, alloferon 2 Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly, Ac-alloferon 1 Ac-His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly and Ac-alloferon 2 Ac-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly have been studied by potentiometric, UV-vis, CD ...
Teresa, Kowalik-Jankowska   +3 more
openaire   +2 more sources

The long‐term immunological effects of alloferon and its analogues in the mealworm Tenebrio molitor

Insect Science, 2017
AbstractThe subject of this article is a search for the long‐term immunological effects of alloferon and 3 structural analogues of alloferon, which were earlier characterized by the highest pro‐apoptotic activity in Tenebrio molitor. The differences in the actions of these peptides on immune response were observed.
Elżbieta, Czarniewska   +3 more
openaire   +2 more sources

High stability and biological activity of the copper(II) complexes of alloferon 1 analogues containing tryptophan

Journal of Inorganic Biochemistry, 2016
Copper(II) complex formation processes between the alloferon 1 (Allo1) (HGVSGHGQHGVHG) analogues where the tryptophan residue is introducing in the place His residue H1W, H6W, H9W and H12W have been studied by potentiometric, UV-visible, CD and EPR spectroscopic, and MS methods. For all analogues of alloferon 1 complex speciation have been obtained for
Agnieszka, Kadej   +5 more
openaire   +2 more sources

Activation of NF-kappaB by alloferon through down-regulation of antioxidant proteins and IkappaBalpha.

Molecular and cellular biochemistry, 2008
Alloferon is a 13-amino acid peptide isolated from the bacteria-challenged larvae of the blow fly Calliphora vicina. The pharmaceutical value of the peptide has been well demonstrated by its capacity to stimulate NK cytotoxic activity and interferon (IFN) synthesis in animal and human models, as well as to enhance antiviral and antitumor activities in ...
Myung-Jeom, Ryu   +7 more
openaire   +1 more source

The effectiveness of Alloferon in the complex therapy of chronic recurrent papillomavirus cystitis

Urologiia, 2021
A.I. Palenyy Palenyy   +3 more
openaire   +1 more source

[Regulation of proliferation and viability of tumor cells in vitro by alloferon-1 and allostatin-1].

Tsitologiia, 2011
Alloferon-1 (AF) and allostatin-1 (AS) cytotoxic and growth modulating activities have been compared. AF is cationic oligopeptide isolated from the hemolymph of experimentally infected blow fly Calliphora vicina. AS is AF synthetic analog that differs from the parent molecule in two amino acids substituted. It has been shown that both AF and AS have no
V A, Pleskach   +5 more
openaire   +1 more source

[The synthesis of immunomodulating peptide alloferon, the active component of the antiviral drug allokine-alpha].

Bioorganicheskaia khimiia, 2006
Two variants of the synthesis of tridecapeptide alloferon, the active principle of antiviral preparation allokine-alpha, were developed on the basis of fragment condensation in solution or on the Merrifield resin. The solid phase variant of the synthesis was shown to be more technological; it allows the preparation of the product at a higher total ...
M V, Sidorova   +7 more
openaire   +1 more source

Alloferon and Zanamivir Show Effective Antiviral Activity against Influenza A Virus (H1N1) Infection In Vitro and In Vivo

International Journal of Molecular Sciences, 2023
Jae Seung Kang, Nam-Hyuk Cho, Dahae Lee
exaly  

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