Results 101 to 110 of about 256,813 (405)

The Role of Fecal Microbiota Transplantation in the Allogeneic Stem Cell Transplant Setting

Microorganisms, 2023
Microbiota changes during allogeneic hematopoietic stem cell transplantation has several known causes: conditioning chemotherapy and radiation, broad-spectrum antibiotic administration, modification in nutrition status and diet, and graft-versus-host ...
Elisabetta Metafuni, Luca Di Marino, Sabrina Giammarco, Silvia Bellesi, Maria Assunta Limongiello, Federica Sorà, Filippo Frioni, Roberto Maggi, Patrizia Chiusolo, Simona Sica   +9 more
doaj   +1 more source

Benchmarking survival outcomes: A funnel plot for survival data [PDF]

arXiv, 2021
Benchmarking is commonly used in many healthcare settings to monitor clinical performance, with the aim of increasing cost-effectiveness and safe care of patients. The funnel plot is a popular tool in visualizing the performance of a healthcare center in relation to other centers and to a target, taking into account statistical uncertainty.
arxiv  

Clinical Effects of Driver Somatic Mutations on the Outcomes of Patients With Myelodysplastic Syndromes Treated With Allogeneic Hematopoietic Stem-Cell Transplantation.

Journal of Clinical Oncology, 2016
PURPOSE The genetic basis of myelodysplastic syndromes (MDS) is heterogeneous, and various combinations of somatic mutations are associated with different clinical phenotypes and outcomes.
M. D. Della Porta, A. Gallì, A. Bacigalupo, S. Zibellini, M. Bernardi, E. Rizzo, B. Allione, M. V. van Lint, P. Pioltelli, P. Marenco, A. Bosi, M. Voso, S. Sica, Mariella Cuzzola, E. Angelucci, M. Rossi, M. Ubezio, A. Malovini, I. Limongelli, V. Ferretti, O. Spinelli, C. Tresoldi, S. Pozzi, S. Luchetti, L. Pezzetti, S. Catricalà, C. Milanesi, A. Riva, B. Bruno, F. Ciceri, F. Bonifazi, R. Bellazzi, E. Papaemmanuil, A. Santoro, E. Alessandrino, A. Rambaldi, M. Cazzola   +36 more
semanticscholar   +1 more source

Diffuse alveolar hemorrhage is most often fatal and is affected by graft source, conditioning regimen toxicity, and engraftment kinetics

Haematologica, 2018
Diffuse alveolar hemorrhage after hematopoietic stem cell transplantation is a frequently fatal complication with no standard therapy. Although significant changes in supportive and intensive care measures for patients undergoing hematopoietic stem cell ...
Fatma Keklik, Ezzideen Barjes Alrawi, Qing Cao, Nelli Bejanyan, Armin Rashidi, Aleksandr Lazaryan, Patrick Arndt, Erhan H. Dincer, Veronika Bachanova, Erica D. Warlick, Margaret L. MacMillan, Mukta Arora, Jeffrey Miller, Claudio G Brunstein, Daniel J. Weisdorf, Celalettin Ustun   +15 more
doaj   +1 more source

Nutritional status and quality of life in adults undergoing allogeneic hematopoietic stem cell transplantation [PDF]

, 2022
Although the effects of malnutrition on morbidity and mortality in adult patients undergoing allogeneic hematopoietic stem cell transplantation are clear, the relationship with quality of life (QOL) is less clear.
Bacigalupo, Andrea (ORCID:0000-0002-9119-567X), Borrelli, Ivan (ORCID:0000-0002-6361-8823), Botti, Stefano, Celli, Danilo, Cioce, Marco, De Stefano, Valerio (ORCID:0000-0002-5178-5827), Galli, Eugenio, Garau, Paola, Giraldi, Alessandra, Lohmeyer, Franziska Michaela, Magini, Marinella, Moscato, Umberto (ORCID:0000-0002-2568-3966), Sica, Simona, Zega, Maurizio (ORCID:0000-0002-7821-2615)   +13 more
core   +1 more source

A Dynamical Systems Perspective on Chimeric Antigen Receptor T-Cell Dosing [PDF]

, 2018
Chimeric antigen receptor T cells (CAR T cells) are dosed similarly to donor lymphocyte infusions following hematopoietic cell transplantation. In this perspective paper a mathematical basis for personalized dosing of CAR T cells is introduced.
arxiv   +1 more source

Correspondence of MRI and nTMS With EDSS in Multiple Sclerosis: Longitudinal Follow‐Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Considering the characteristics of multiple sclerosis (MS) disease and its impact on motor disability, this study aims to assess the functional integrity of the corticospinal tract by examining motor evoked potentials (MEPs), Expanded Disability Status Scale (EDSS) scores, magnetic resonance imaging (MRI) lesion counts, and ...
Antonia Bralić, Sanda Pavelin, Nikolina Pleić, Joško Šoda, Krešimir Dolić, Anita Markotić, Ana Ćurković Katić, Angela Mastelić, Nikolina Režić Mužinić, Jasna Duranović, Zlatko Kljajić, Ivona Stipica Safić, Zoran Đogaš, Maja Rogić Vidaković   +13 more
wiley   +1 more source

Posttransplantation course after allogeneic stem cell transplantation in a patient with advanced mycosis fungoides—Balancing relapse and rejection

JEADV Clinical Practice
Treatment of advanced cutaneous T‐cell lymphoma (CTCL) can be challenging. To date, the only potentially curative treatment option for advanced CTCL is allogeneic hematopoietic stem cell transplantation.
Inga Hansen‐Abeck, Chiara L. Blomen, Finn Abeck, Leopold Torster, Stefan W. Schneider, Nina Booken   +5 more
doaj   +1 more source

Targeted Penetrating Motif Engineering of BH3 Mimetic: Harnessing Non‐Canonical Amino Acids for Coinhibition of MCL‐1 and BCL‐xL in Acute Myeloid Leukemia

Advanced Science, EarlyView.
A structure‐guided peptide derived from a non‐canonical amino acid library simultaneously targets MCL‐1 and BCL‐xL to overcome apoptotic resistance in acute myeloid leukemia. Fused with a CXCR4‐binding motif, the engineered peptide exhibits selective intracellular delivery and potent in vivo efficacy, offering a promising therapeutic strategy against ...
Zhe Wang, Ruizhi Lai, Xinpei Wang, Xu Chen, Youjian Zhou, Shengbin Li, Xiaohui Qiu, Zekai Zeng, Jianye Yuan, Jinghuan Mao, Zhidong Chen, Junqing Wang   +11 more
wiley   +1 more source

Reduced exercise capacity is associated with left ventricular systolic dysfunction in long‐term survivors of allogeneic hematopoietic stem‐cell transplantation

Journal of Clinical Ultrasound, Volume 51, Issue 1, Page 5-15, January 2023., 2023
Exercise intolerance is a common complication in long‐term survivors of allogeneic hematopoietic stem‐cell transplantation. In this study, we found reduced oxygen uptake (VO2peak) by cardio‐pulmonary exercise tests to be associated with left ventricular systolic dysfunction by echocardiography.
Richard John Massey, Ole Henrik Myrdal, Phoi Phoi Diep, Marta Maria Burman, Lorentz Brinch, Lars Lysgaard Gullestad, Ellen Ruud, Svend Aakhus, Jan Otto Beitnes   +8 more
wiley   +1 more source