Relationship between HLA alleles and cytomegalovirus infection after allogeneic hematopoietic stem cell transplant [PDF]
Yolande Chen+12 more
openalex +1 more source
Pathogenetic role of tissue factor in graft-versus-host disease [PDF]
Graft-versus-host disease (GVHD) is a serious complication after allogeneic stem cell transplantation, the mechanism of it is still not elucidated.
Li Quan+3 more
core +1 more source
Design Principle of Gene Expression Used by Human Stem Cells; Implication for Pluripotency [PDF]
Human embryonic stem cells (ESC) are undifferentiated and are endowed with the capacities of self renewal and pluripotential differentiation. Adult stem cells renew their own tissue, but whether they can trans-differentiate to other tissues is still controversial.
arxiv
Three potential sources of cell injuries of lymphoid cells associated with developments of lymphoid leukemia and lymphoma [PDF]
Lymphoid leukemia (LL) and lymphoma are blood cancers developed from lymphoid cells (LCs). To understand the cause and the mechanism of cell transformation of a LC, we studied the potential sources of cell injuries of LCs and analyzed how DNA changes are generated and accumulate in LCs. I.
arxiv
Incidence and outcome of bacterial and fungal infections following nonmyeloablative compared with myeloablative allogeneic hematopoietic stem cell transplantation: A matched control study [PDF]
Christian Junghanß+8 more
openalex +1 more source
Brain atrophy measures can reliably assess the effects of treatment in patients with multiple sclerosis. Using a robust longitudinal method, we demonstrated that, after a short period of pseudoatrophy, treatment with cladribine tablets significantly reduced grey matter atrophy in comparison with placebo.
Rosa Cortese+7 more
wiley +1 more source
Stem cell therapeutics: potential in the treatment of inflammatory bowel disease
ES Swenson1, ND Theise21Department of Internal Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT, USA; 2Departments of Pathology and Medicine (Division of Digestive Diseases), Beth Israel Medical Center –
ES Swenson, ND Theise
doaj
Whole Exome Sequencing to Estimate Alloreactivity Potential Between Donors and Recipients in Stem Cell Transplantation [PDF]
Whole exome sequencing was performed on HLA-matched stem cell donors and transplant recipients to measure sequence variation contributing to minor histocompatibility antigen differences between the two. A large number of nonsynonymous single nucleotide polymorphisms were identified in each of the nine unique donor-recipient pairs tested. This variation
arxiv
From simplicity to complexity in current melanoma models
Abstract Despite the recent impressive clinical success of immunotherapy against melanoma, development of primary and adaptive resistance against immune checkpoint inhibitors remains a major issue in a large number of treated patients. This highlights the need for melanoma models that replicate the tumor's intricate dynamics in the tumor ...
Elisabetta Michielon+2 more
wiley +1 more source
Late cytomegalovirus disease and mortality in recipients of allogeneic hematopoietic stem cell transplants: importance of viral load and T-cell immunity [PDF]
Michael Boeckh+9 more
openalex +1 more source