Results 201 to 210 of about 58,791 (313)

Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir

British Journal of Pharmacology, EarlyView.
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy, Sophie Post, Wing Hang Ip, Elin Hahlin, Sebastian Kühn, Andrea Pirosu, Christian Conze, Martin Baumdick, Hamburg Intestinal Study Group, Madeleine J. Bunders, Britta F. Zecher, Angelique Hoelzemer, Stephan Linder, Niklas Arnberg, Thomas Dobner, Marcus Altfeld, Sebastian Schloer   +16 more
wiley   +1 more source

Microbiome-based prediction of allogeneic hematopoietic stem cell transplantation outcome. [PDF]

Genome Med
Shtossel O, Eshel A, Fried S, Geva M, Danylesko I, Yerushalmi R, Shem-Tov N, Fein JA, Fabbrini M, Shimoni A, Turjeman S, Louzoun Y, Nagler A, Koren O, Shouval R.   +14 more
europepmc   +1 more source

Humoral and functional SARS‐CoV‐2‐specific T‐cell responses elicited in chronic lymphocytic leukaemia patients with GEO‐CM04S1 a synthetic MVA‐vectored COVID‐19 vaccine

British Journal of Haematology, EarlyView.
Sandra Ortega‐Francisco, Maria Teresa Prudente de Aquino, Corinna La Rosa, Flavia Chiuppesi, Miguel‐Angel Gutierrez, Jacqueline Miller, Jing Li, Jada Mack‐Onyeike, Yifei Zhou, Qiao Zhou, Teodora Kaltcheva, Angela Patterson, Shannon Dempsey, Sandra Thomas, Katrin Tiemann, Dongyun Yang, Wasima Rida, Felix Wussow, Kelly McKee, Randy Taplitz, Erica Raiden, Tanya Siddiqi, Steven Rosen, Don J. Diamond, Alexey Danilov   +24 more
wiley   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Allogeneic Hematopoietic Stem Cell Transplantation for Infant Leukemia: A Single-Center Case Series and Narrative Review. [PDF]

Children (Basel)
Kostareva I, Kirgizov K, Shubina I, Stepanyan N, Batmanova N, Valiev T, Kiselevsky M, Varfolomeeva S.   +7 more
europepmc   +1 more source

Real‐world experience with CPX‐351 for secondary acute myeloid leukaemia: Comparison with FLAG‐IDA in a propensity score matching analysis

British Journal of Haematology, EarlyView.
Maria Agustina Perusini, Ana Flavia Patiño, Claire Andrews, Sarit E. Assouline, Joseph M. Brandwein, Signy Chow, Gizelle Popradi, David Sanford, Lynn Savoie, Lalit Saini, Bambace Nadia, Dina Khalaf, Andre C. Schuh, Karen Yee, Vikas Gupta, Dawn Maze, Steven M. Chan, Aaron D. Schimmer, Waleed Sabry, Hassan Sibai   +19 more
wiley   +1 more source

Phase 1/2 Study of Crizotinib in Children With Relapsed/Refractory ALK‐Positive Anaplastic Large Cell Lymphoma or Neuroblastoma in Japan

Cancer Science, EarlyView.
The safety and antitumor activity of crizotinib at a dose of 165 mg/m2 BID were evaluated in 16 patients with ALK‐positive ALCL in Japan. The most common grade 3 or 4 adverse event was neutropenia. The steady‐state Cmax and AUCtau of crizotinib at 165 mg/m2 BID were higher than expected. The objective response rate was 72.7% (90% CI, 43.6%–92.1%) among
Tetsuya Mori, Akiko Kada, Tomoo Osumi, Daisuke Tomizawa, Yuhki Koga, Reiji Fukano, Kengo Takeuchi, Ukihide Tateishi, Osamu Miyazaki, Ryuta Asada, Akiko M. Saito, Kei Fukuhara, Masahiro Sekimizu   +12 more
wiley   +1 more source

Allogeneic Hematopoietic Stem Cell Transplantation in Adolescents and Young Adults With Acute Lymphoblastic Leukemia-A Retrospective, Dual-Center Study. [PDF]

Am J Hematol
Pasvolsky O, Shimony S, Saliba RM, Marcoux C, Ledesma C, Rondon G, Tewari P, Ragoonanan D, Short NJ, Jabbour E, Gooptu M, Ho VT, Soiffer RJ, Antin JH, Koreth J, Cutler CS, Paolino JD, Duncan CN, Lehmann LE, DeAngelo DJ, Jain N, Champlin R, Shpall E, Luskin MR, Kebriaei P.   +24 more
europepmc   +1 more source

Clinical Practice Guideline for the Treatment of BK-Virus Induced Hemorrhagic Cystitis in the Post-Allogeneic Hematopoietic Stem Cell Transplant Setting

, 2012
Devi D Morrison, Thomas Samith Kochuparambil, David L. DeRemer, Vamsi Kota, Anand Jillella, Farrukh T. Awan   +5 more
openalex   +1 more source

Safety and effectiveness of the combination of 5‐azacitidine and ruxolitinib in VEXAS syndrome: A single‐centre experience

British Journal of Haematology, EarlyView.
Gregorio Maria Bergonzi, Enrico Cozzo, Alessandro Tomelleri, Costanza Piccolo, Gianluca Scorpio, Carmelo Gurnari, Francesca Romano, Marco Matucci‐Cerinic, Lorenzo Dagna, Massimo Bernardi, Luca Vago, Fabio Ciceri, Corrado Campochiaro, Elisa Diral   +13 more
wiley   +1 more source